| Full name: cut like homeobox 1 | Alias Symbol: CDP|CDP1|CUX|CUT|Clox|CDP/Cut|CDP/Cux|Cux/CDP|CASP|GOLIM6 | ||
| Type: protein-coding gene | Cytoband: 7q22.1 | ||
| Entrez ID: 1523 | HGNC ID: HGNC:2557 | Ensembl Gene: ENSG00000257923 | OMIM ID: 116896 |
| Drug and gene relationship at DGIdb | |||
Expression of CUX1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CUX1 | 1523 | 214743_at | 1.0815 | 0.0124 | |
| GSE20347 | CUX1 | 1523 | 214743_at | 1.0899 | 0.0000 | |
| GSE23400 | CUX1 | 1523 | 214743_at | 0.6907 | 0.0000 | |
| GSE26886 | CUX1 | 1523 | 214743_at | 1.6623 | 0.0000 | |
| GSE29001 | CUX1 | 1523 | 214743_at | 0.8166 | 0.0004 | |
| GSE38129 | CUX1 | 1523 | 214743_at | 0.8558 | 0.0000 | |
| GSE45670 | CUX1 | 1523 | 214743_at | 1.0775 | 0.0000 | |
| GSE53622 | CUX1 | 1523 | 100379 | 0.8851 | 0.0000 | |
| GSE53624 | CUX1 | 1523 | 38410 | -0.0947 | 0.2183 | |
| GSE63941 | CUX1 | 1523 | 214743_at | -0.3368 | 0.4944 | |
| GSE77861 | CUX1 | 1523 | 214743_at | 1.5698 | 0.0008 | |
| GSE97050 | CUX1 | 1523 | A_24_P220454 | 0.2605 | 0.5569 | |
| SRP007169 | CUX1 | 1523 | RNAseq | 0.2551 | 0.4572 | |
| SRP008496 | CUX1 | 1523 | RNAseq | 0.3146 | 0.1753 | |
| SRP064894 | CUX1 | 1523 | RNAseq | -0.2086 | 0.2305 | |
| SRP133303 | CUX1 | 1523 | RNAseq | 0.5908 | 0.0078 | |
| SRP159526 | CUX1 | 1523 | RNAseq | 0.0495 | 0.8515 | |
| SRP193095 | CUX1 | 1523 | RNAseq | 0.2786 | 0.0318 | |
| SRP219564 | CUX1 | 1523 | RNAseq | -0.0216 | 0.9584 | |
| TCGA | CUX1 | 1523 | RNAseq | -0.0164 | 0.7310 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by CUX1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CUX1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CUX1 | 1523 | 14 | 0 | 16 | |
| GSE20123 | CUX1 | 1523 | 14 | 0 | 16 | |
| GSE43470 | CUX1 | 1523 | 7 | 2 | 34 | |
| GSE46452 | CUX1 | 1523 | 10 | 1 | 48 | |
| GSE47630 | CUX1 | 1523 | 7 | 3 | 30 | |
| GSE54993 | CUX1 | 1523 | 1 | 10 | 59 | |
| GSE54994 | CUX1 | 1523 | 15 | 4 | 34 | |
| GSE60625 | CUX1 | 1523 | 0 | 0 | 11 | |
| GSE74703 | CUX1 | 1523 | 7 | 1 | 28 | |
| GSE74704 | CUX1 | 1523 | 10 | 0 | 10 | |
| TCGA | CUX1 | 1523 | 51 | 8 | 37 |
Total number of gains: 136; Total number of losses: 29; Total Number of normals: 323.
Somatic mutations of CUX1:
Generating mutation plots.
Highly correlated genes for CUX1:
Showing top 20/1678 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CUX1 | LCLAT1 | 0.785178 | 6 | 0 | 6 |
| CUX1 | ZC3H18 | 0.772033 | 4 | 0 | 4 |
| CUX1 | CMSS1 | 0.758562 | 5 | 0 | 5 |
| CUX1 | CASC4 | 0.755517 | 3 | 0 | 3 |
| CUX1 | ZNF827 | 0.745463 | 6 | 0 | 6 |
| CUX1 | TET1 | 0.744205 | 3 | 0 | 3 |
| CUX1 | WDR66 | 0.742246 | 5 | 0 | 5 |
| CUX1 | RILPL1 | 0.741692 | 3 | 0 | 3 |
| CUX1 | UBE2T | 0.737517 | 5 | 0 | 5 |
| CUX1 | XPR1 | 0.736192 | 6 | 0 | 6 |
| CUX1 | MRPL47 | 0.733332 | 6 | 0 | 6 |
| CUX1 | INPP5B | 0.727982 | 3 | 0 | 3 |
| CUX1 | BLACAT1 | 0.72792 | 3 | 0 | 3 |
| CUX1 | MFHAS1 | 0.726738 | 11 | 0 | 10 |
| CUX1 | PLXNA1 | 0.724392 | 10 | 0 | 10 |
| CUX1 | EXOC6 | 0.722695 | 3 | 0 | 3 |
| CUX1 | IDS | 0.718891 | 3 | 0 | 3 |
| CUX1 | NAV2 | 0.715104 | 3 | 0 | 3 |
| CUX1 | C1orf131 | 0.714338 | 6 | 0 | 6 |
| CUX1 | C4orf48 | 0.714011 | 5 | 0 | 5 |
For details and further investigation, click here
