| Full name: signal recognition particle 9 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q42.12 | ||
| Entrez ID: 6726 | HGNC ID: HGNC:11304 | Ensembl Gene: ENSG00000143742 | OMIM ID: 600707 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SRP9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SRP9 | 6726 | 201273_s_at | 0.0764 | 0.7902 | |
| GSE20347 | SRP9 | 6726 | 201273_s_at | 0.1761 | 0.2583 | |
| GSE23400 | SRP9 | 6726 | 201273_s_at | 0.3544 | 0.0000 | |
| GSE26886 | SRP9 | 6726 | 201273_s_at | -0.2212 | 0.2547 | |
| GSE29001 | SRP9 | 6726 | 201273_s_at | 0.3009 | 0.5307 | |
| GSE38129 | SRP9 | 6726 | 201273_s_at | 0.2363 | 0.0304 | |
| GSE45670 | SRP9 | 6726 | 201273_s_at | 0.0956 | 0.3803 | |
| GSE53622 | SRP9 | 6726 | 3187 | -0.1998 | 0.0005 | |
| GSE53624 | SRP9 | 6726 | 66217 | 0.1403 | 0.0094 | |
| GSE63941 | SRP9 | 6726 | 201273_s_at | -0.1237 | 0.5679 | |
| GSE77861 | SRP9 | 6726 | 201273_s_at | 0.0234 | 0.8639 | |
| GSE97050 | SRP9 | 6726 | A_24_P66528 | 0.2463 | 0.4168 | |
| SRP007169 | SRP9 | 6726 | RNAseq | -0.6135 | 0.0728 | |
| SRP008496 | SRP9 | 6726 | RNAseq | -0.2312 | 0.4114 | |
| SRP064894 | SRP9 | 6726 | RNAseq | -0.0656 | 0.6450 | |
| SRP133303 | SRP9 | 6726 | RNAseq | 0.4046 | 0.0182 | |
| SRP159526 | SRP9 | 6726 | RNAseq | 0.2816 | 0.3187 | |
| SRP193095 | SRP9 | 6726 | RNAseq | -0.2674 | 0.0364 | |
| SRP219564 | SRP9 | 6726 | RNAseq | -0.2255 | 0.1765 | |
| TCGA | SRP9 | 6726 | RNAseq | 0.0902 | 0.0296 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SRP9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SRP9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SRP9 | 6726 | 11 | 0 | 19 | |
| GSE20123 | SRP9 | 6726 | 11 | 0 | 19 | |
| GSE43470 | SRP9 | 6726 | 7 | 1 | 35 | |
| GSE46452 | SRP9 | 6726 | 3 | 1 | 55 | |
| GSE47630 | SRP9 | 6726 | 15 | 0 | 25 | |
| GSE54993 | SRP9 | 6726 | 0 | 6 | 64 | |
| GSE54994 | SRP9 | 6726 | 16 | 0 | 37 | |
| GSE60625 | SRP9 | 6726 | 0 | 0 | 11 | |
| GSE74703 | SRP9 | 6726 | 7 | 1 | 28 | |
| GSE74704 | SRP9 | 6726 | 5 | 0 | 15 | |
| TCGA | SRP9 | 6726 | 46 | 3 | 47 |
Total number of gains: 121; Total number of losses: 12; Total Number of normals: 355.
Somatic mutations of SRP9:
Generating mutation plots.
Highly correlated genes for SRP9:
Showing top 20/612 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SRP9 | PRDM15 | 0.79153 | 3 | 0 | 3 |
| SRP9 | PEX11B | 0.777299 | 3 | 0 | 3 |
| SRP9 | VPS26B | 0.773085 | 3 | 0 | 3 |
| SRP9 | C6orf62 | 0.762587 | 4 | 0 | 4 |
| SRP9 | REST | 0.759201 | 3 | 0 | 3 |
| SRP9 | KDM5B | 0.751782 | 3 | 0 | 3 |
| SRP9 | PTPRF | 0.74232 | 3 | 0 | 3 |
| SRP9 | PPIP5K2 | 0.741118 | 3 | 0 | 3 |
| SRP9 | UNC5CL | 0.738234 | 3 | 0 | 3 |
| SRP9 | RAP1GDS1 | 0.73664 | 3 | 0 | 3 |
| SRP9 | C2CD2 | 0.734131 | 3 | 0 | 3 |
| SRP9 | LY75 | 0.727534 | 3 | 0 | 3 |
| SRP9 | NBPF1 | 0.725637 | 3 | 0 | 3 |
| SRP9 | ALG14 | 0.722071 | 3 | 0 | 3 |
| SRP9 | PRKX | 0.703356 | 3 | 0 | 3 |
| SRP9 | GTF3C4 | 0.700768 | 3 | 0 | 3 |
| SRP9 | DR1 | 0.698857 | 5 | 0 | 4 |
| SRP9 | RASA2 | 0.695211 | 4 | 0 | 3 |
| SRP9 | COMMD2 | 0.694677 | 3 | 0 | 3 |
| SRP9 | SLC39A11 | 0.692186 | 3 | 0 | 3 |
For details and further investigation, click here
