| Full name: phosphatidylinositol glycan anchor biosynthesis class C | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q24.3 | ||
| Entrez ID: 5279 | HGNC ID: HGNC:8960 | Ensembl Gene: ENSG00000135845 | OMIM ID: 601730 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of PIGC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PIGC | 5279 | 202846_s_at | 0.2577 | 0.2596 | |
| GSE20347 | PIGC | 5279 | 202846_s_at | 0.6252 | 0.0000 | |
| GSE23400 | PIGC | 5279 | 202846_s_at | 0.4671 | 0.0000 | |
| GSE26886 | PIGC | 5279 | 202846_s_at | 0.0920 | 0.6699 | |
| GSE29001 | PIGC | 5279 | 202846_s_at | 0.7602 | 0.0018 | |
| GSE38129 | PIGC | 5279 | 202846_s_at | 0.6442 | 0.0000 | |
| GSE45670 | PIGC | 5279 | 202846_s_at | 0.1564 | 0.1796 | |
| GSE53622 | PIGC | 5279 | 42658 | 0.3693 | 0.0000 | |
| GSE53624 | PIGC | 5279 | 42658 | 0.5849 | 0.0000 | |
| GSE63941 | PIGC | 5279 | 202846_s_at | 0.2337 | 0.6229 | |
| GSE77861 | PIGC | 5279 | 202846_s_at | 0.4825 | 0.0029 | |
| GSE97050 | PIGC | 5279 | A_23_P86252 | 0.0461 | 0.8570 | |
| SRP007169 | PIGC | 5279 | RNAseq | -0.4234 | 0.2590 | |
| SRP008496 | PIGC | 5279 | RNAseq | 0.6011 | 0.1141 | |
| SRP064894 | PIGC | 5279 | RNAseq | 0.5518 | 0.0008 | |
| SRP133303 | PIGC | 5279 | RNAseq | 0.2796 | 0.0404 | |
| SRP159526 | PIGC | 5279 | RNAseq | 0.5735 | 0.0021 | |
| SRP193095 | PIGC | 5279 | RNAseq | 0.1842 | 0.0604 | |
| SRP219564 | PIGC | 5279 | RNAseq | 0.6012 | 0.0048 | |
| TCGA | PIGC | 5279 | RNAseq | 0.1741 | 0.0033 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PIGC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PIGC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PIGC | 5279 | 12 | 0 | 18 | |
| GSE20123 | PIGC | 5279 | 12 | 0 | 18 | |
| GSE43470 | PIGC | 5279 | 7 | 2 | 34 | |
| GSE46452 | PIGC | 5279 | 3 | 1 | 55 | |
| GSE47630 | PIGC | 5279 | 14 | 0 | 26 | |
| GSE54993 | PIGC | 5279 | 0 | 6 | 64 | |
| GSE54994 | PIGC | 5279 | 16 | 0 | 37 | |
| GSE60625 | PIGC | 5279 | 0 | 0 | 11 | |
| GSE74703 | PIGC | 5279 | 7 | 2 | 27 | |
| GSE74704 | PIGC | 5279 | 6 | 0 | 14 | |
| TCGA | PIGC | 5279 | 43 | 3 | 50 |
Total number of gains: 120; Total number of losses: 14; Total Number of normals: 354.
Somatic mutations of PIGC:
Generating mutation plots.
Highly correlated genes for PIGC:
Showing top 20/1463 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PIGC | AFAP1 | 0.808342 | 4 | 0 | 4 |
| PIGC | PPTC7 | 0.786867 | 3 | 0 | 3 |
| PIGC | MCMBP | 0.756816 | 3 | 0 | 3 |
| PIGC | ZFYVE27 | 0.75229 | 3 | 0 | 3 |
| PIGC | KRTCAP2 | 0.749753 | 4 | 0 | 4 |
| PIGC | ZNF551 | 0.749614 | 3 | 0 | 3 |
| PIGC | RNF217 | 0.749242 | 4 | 0 | 4 |
| PIGC | WDR81 | 0.748308 | 4 | 0 | 3 |
| PIGC | SLC39A3 | 0.746421 | 3 | 0 | 3 |
| PIGC | WDR37 | 0.739082 | 3 | 0 | 3 |
| PIGC | WDR5 | 0.736786 | 4 | 0 | 3 |
| PIGC | PET117 | 0.73582 | 3 | 0 | 3 |
| PIGC | PACS1 | 0.733525 | 3 | 0 | 3 |
| PIGC | PTGFRN | 0.719671 | 3 | 0 | 3 |
| PIGC | KDM5B | 0.719334 | 3 | 0 | 3 |
| PIGC | SSBP4 | 0.717001 | 4 | 0 | 3 |
| PIGC | C20orf194 | 0.716979 | 3 | 0 | 3 |
| PIGC | NAV2 | 0.713272 | 3 | 0 | 3 |
| PIGC | ABCB6 | 0.713248 | 3 | 0 | 3 |
| PIGC | DPYSL2 | 0.712578 | 4 | 0 | 3 |
For details and further investigation, click here
