| Full name: GRAM domain containing 4 | Alias Symbol: KIAA0767|DIP | ||
| Type: protein-coding gene | Cytoband: 22q13.31 | ||
| Entrez ID: 23151 | HGNC ID: HGNC:29113 | Ensembl Gene: ENSG00000075240 | OMIM ID: 613691 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GRAMD4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GRAMD4 | 23151 | 212856_at | 0.6915 | 0.2213 | |
| GSE20347 | GRAMD4 | 23151 | 212856_at | -0.1748 | 0.3472 | |
| GSE23400 | GRAMD4 | 23151 | 212856_at | 0.0504 | 0.4927 | |
| GSE26886 | GRAMD4 | 23151 | 212856_at | 0.2202 | 0.3872 | |
| GSE29001 | GRAMD4 | 23151 | 212856_at | 0.0316 | 0.8966 | |
| GSE38129 | GRAMD4 | 23151 | 212856_at | -0.0130 | 0.9379 | |
| GSE45670 | GRAMD4 | 23151 | 212856_at | 0.2642 | 0.0338 | |
| GSE53622 | GRAMD4 | 23151 | 157744 | -0.1941 | 0.0265 | |
| GSE53624 | GRAMD4 | 23151 | 157744 | -0.2907 | 0.0003 | |
| GSE63941 | GRAMD4 | 23151 | 212856_at | -1.2922 | 0.0122 | |
| GSE77861 | GRAMD4 | 23151 | 1569154_a_at | 0.0494 | 0.7645 | |
| GSE97050 | GRAMD4 | 23151 | A_24_P23258 | 0.1219 | 0.6701 | |
| SRP007169 | GRAMD4 | 23151 | RNAseq | -0.6142 | 0.1797 | |
| SRP008496 | GRAMD4 | 23151 | RNAseq | -0.5279 | 0.0836 | |
| SRP064894 | GRAMD4 | 23151 | RNAseq | 0.2029 | 0.3522 | |
| SRP133303 | GRAMD4 | 23151 | RNAseq | -0.2984 | 0.0730 | |
| SRP159526 | GRAMD4 | 23151 | RNAseq | -0.1862 | 0.3885 | |
| SRP193095 | GRAMD4 | 23151 | RNAseq | -0.1137 | 0.3985 | |
| SRP219564 | GRAMD4 | 23151 | RNAseq | -0.0593 | 0.8601 | |
| TCGA | GRAMD4 | 23151 | RNAseq | -0.1416 | 0.0170 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GRAMD4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GRAMD4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GRAMD4 | 23151 | 5 | 6 | 19 | |
| GSE20123 | GRAMD4 | 23151 | 4 | 5 | 21 | |
| GSE43470 | GRAMD4 | 23151 | 2 | 6 | 35 | |
| GSE46452 | GRAMD4 | 23151 | 31 | 2 | 26 | |
| GSE47630 | GRAMD4 | 23151 | 9 | 4 | 27 | |
| GSE54993 | GRAMD4 | 23151 | 3 | 6 | 61 | |
| GSE54994 | GRAMD4 | 23151 | 11 | 7 | 35 | |
| GSE60625 | GRAMD4 | 23151 | 5 | 0 | 6 | |
| GSE74703 | GRAMD4 | 23151 | 2 | 4 | 30 | |
| GSE74704 | GRAMD4 | 23151 | 2 | 3 | 15 | |
| TCGA | GRAMD4 | 23151 | 28 | 17 | 51 |
Total number of gains: 102; Total number of losses: 60; Total Number of normals: 326.
Somatic mutations of GRAMD4:
Generating mutation plots.
Highly correlated genes for GRAMD4:
Showing top 20/164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GRAMD4 | CHD3 | 0.748417 | 3 | 0 | 3 |
| GRAMD4 | DERL1 | 0.7299 | 3 | 0 | 3 |
| GRAMD4 | CCDC127 | 0.729009 | 3 | 0 | 3 |
| GRAMD4 | RNF114 | 0.7224 | 3 | 0 | 3 |
| GRAMD4 | ASXL1 | 0.718467 | 3 | 0 | 3 |
| GRAMD4 | UTP23 | 0.71806 | 3 | 0 | 3 |
| GRAMD4 | GNPDA1 | 0.716287 | 3 | 0 | 3 |
| GRAMD4 | C4orf47 | 0.715113 | 3 | 0 | 3 |
| GRAMD4 | TAP1 | 0.712486 | 3 | 0 | 3 |
| GRAMD4 | DROSHA | 0.712078 | 3 | 0 | 3 |
| GRAMD4 | BCL2A1 | 0.706339 | 3 | 0 | 3 |
| GRAMD4 | RFNG | 0.703615 | 3 | 0 | 3 |
| GRAMD4 | SYCP2 | 0.701217 | 3 | 0 | 3 |
| GRAMD4 | NDUFS6 | 0.699815 | 3 | 0 | 3 |
| GRAMD4 | RNF4 | 0.6976 | 3 | 0 | 3 |
| GRAMD4 | TMEM200A | 0.693095 | 3 | 0 | 3 |
| GRAMD4 | BBS4 | 0.688614 | 3 | 0 | 3 |
| GRAMD4 | GPR137B | 0.687343 | 4 | 0 | 3 |
| GRAMD4 | ARHGEF16 | 0.683321 | 5 | 0 | 4 |
| GRAMD4 | UCN | 0.683223 | 3 | 0 | 3 |
For details and further investigation, click here
