| Full name: CXXC repeat containing interactor of PDZ3 domain | Alias Symbol: HSPC139 | ||
| Type: protein-coding gene | Cytoband: 2p21 | ||
| Entrez ID: 9419 | HGNC ID: HGNC:14312 | Ensembl Gene: ENSG00000119878 | OMIM ID: 604594 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of CRIPT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CRIPT | 9419 | 227942_s_at | 0.0679 | 0.8793 | |
| GSE20347 | CRIPT | 9419 | 218643_s_at | 0.1285 | 0.6464 | |
| GSE23400 | CRIPT | 9419 | 218643_s_at | 0.2313 | 0.0000 | |
| GSE26886 | CRIPT | 9419 | 222702_x_at | 0.0019 | 0.9930 | |
| GSE29001 | CRIPT | 9419 | 218643_s_at | 0.2917 | 0.2076 | |
| GSE38129 | CRIPT | 9419 | 218643_s_at | 0.2892 | 0.1325 | |
| GSE45670 | CRIPT | 9419 | 227942_s_at | 0.3619 | 0.0060 | |
| GSE53622 | CRIPT | 9419 | 75379 | 0.2516 | 0.0000 | |
| GSE53624 | CRIPT | 9419 | 75379 | 0.3770 | 0.0000 | |
| GSE63941 | CRIPT | 9419 | 227942_s_at | 0.5365 | 0.1772 | |
| GSE77861 | CRIPT | 9419 | 227942_s_at | 0.0488 | 0.8660 | |
| GSE97050 | CRIPT | 9419 | A_33_P3251989 | 0.0022 | 0.9953 | |
| SRP007169 | CRIPT | 9419 | RNAseq | 0.4572 | 0.2874 | |
| SRP008496 | CRIPT | 9419 | RNAseq | 0.8686 | 0.0009 | |
| SRP064894 | CRIPT | 9419 | RNAseq | -0.0157 | 0.8997 | |
| SRP133303 | CRIPT | 9419 | RNAseq | 0.2071 | 0.0970 | |
| SRP159526 | CRIPT | 9419 | RNAseq | 0.6123 | 0.0042 | |
| SRP193095 | CRIPT | 9419 | RNAseq | 0.0926 | 0.2582 | |
| SRP219564 | CRIPT | 9419 | RNAseq | -0.0178 | 0.9458 | |
| TCGA | CRIPT | 9419 | RNAseq | 0.1740 | 0.0026 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CRIPT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CRIPT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CRIPT | 9419 | 10 | 1 | 19 | |
| GSE20123 | CRIPT | 9419 | 8 | 1 | 21 | |
| GSE43470 | CRIPT | 9419 | 5 | 0 | 38 | |
| GSE46452 | CRIPT | 9419 | 1 | 4 | 54 | |
| GSE47630 | CRIPT | 9419 | 7 | 0 | 33 | |
| GSE54993 | CRIPT | 9419 | 0 | 5 | 65 | |
| GSE54994 | CRIPT | 9419 | 10 | 0 | 43 | |
| GSE60625 | CRIPT | 9419 | 0 | 3 | 8 | |
| GSE74703 | CRIPT | 9419 | 5 | 0 | 31 | |
| GSE74704 | CRIPT | 9419 | 9 | 1 | 10 | |
| TCGA | CRIPT | 9419 | 35 | 2 | 59 |
Total number of gains: 90; Total number of losses: 17; Total Number of normals: 381.
Somatic mutations of CRIPT:
Generating mutation plots.
Highly correlated genes for CRIPT:
Showing top 20/361 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CRIPT | NDUFA6 | 0.75202 | 3 | 0 | 3 |
| CRIPT | MBD5 | 0.715121 | 3 | 0 | 3 |
| CRIPT | F2RL1 | 0.714817 | 4 | 0 | 4 |
| CRIPT | FOXK2 | 0.703933 | 3 | 0 | 3 |
| CRIPT | EFNB2 | 0.703496 | 3 | 0 | 3 |
| CRIPT | MCFD2 | 0.700548 | 4 | 0 | 3 |
| CRIPT | U2SURP | 0.698733 | 3 | 0 | 3 |
| CRIPT | SLC30A6 | 0.69681 | 3 | 0 | 3 |
| CRIPT | NUS1 | 0.694953 | 4 | 0 | 3 |
| CRIPT | ATG13 | 0.683256 | 3 | 0 | 3 |
| CRIPT | PPP1R14C | 0.678642 | 3 | 0 | 3 |
| CRIPT | NPC1 | 0.671758 | 3 | 0 | 3 |
| CRIPT | DHX57 | 0.671547 | 7 | 0 | 6 |
| CRIPT | LDHA | 0.670509 | 4 | 0 | 3 |
| CRIPT | TMEM45A | 0.6697 | 3 | 0 | 3 |
| CRIPT | NF1 | 0.669237 | 3 | 0 | 3 |
| CRIPT | ZDHHC4 | 0.668652 | 3 | 0 | 3 |
| CRIPT | FAHD1 | 0.66846 | 4 | 0 | 3 |
| CRIPT | C8orf76 | 0.667743 | 3 | 0 | 3 |
| CRIPT | DNAJC8 | 0.665883 | 3 | 0 | 3 |
For details and further investigation, click here
