| Full name: non-SMC condensin II complex subunit H2 | Alias Symbol: 384D8-2|hCAP-H2|CAP-H2 | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 29781 | HGNC ID: HGNC:25071 | Ensembl Gene: ENSG00000025770 | OMIM ID: 611230 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NCAPH2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NCAPH2 | 29781 | 205086_s_at | 0.3163 | 0.2830 | |
| GSE20347 | NCAPH2 | 29781 | 205086_s_at | 0.3496 | 0.0060 | |
| GSE23400 | NCAPH2 | 29781 | 40640_at | -0.0769 | 0.0097 | |
| GSE26886 | NCAPH2 | 29781 | 205086_s_at | 0.8868 | 0.0000 | |
| GSE29001 | NCAPH2 | 29781 | 40640_at | -0.0876 | 0.5104 | |
| GSE38129 | NCAPH2 | 29781 | 205086_s_at | 0.3286 | 0.0006 | |
| GSE45670 | NCAPH2 | 29781 | 205086_s_at | 0.1621 | 0.2689 | |
| GSE53622 | NCAPH2 | 29781 | 19721 | 0.3706 | 0.0000 | |
| GSE53624 | NCAPH2 | 29781 | 19721 | 0.6704 | 0.0000 | |
| GSE63941 | NCAPH2 | 29781 | 205086_s_at | 1.6360 | 0.0022 | |
| GSE77861 | NCAPH2 | 29781 | 205086_s_at | 0.2583 | 0.1910 | |
| GSE97050 | NCAPH2 | 29781 | A_33_P3272558 | 0.0626 | 0.8415 | |
| SRP007169 | NCAPH2 | 29781 | RNAseq | 0.4674 | 0.3200 | |
| SRP008496 | NCAPH2 | 29781 | RNAseq | 0.7848 | 0.0092 | |
| SRP064894 | NCAPH2 | 29781 | RNAseq | 1.1502 | 0.0000 | |
| SRP133303 | NCAPH2 | 29781 | RNAseq | 0.6521 | 0.0019 | |
| SRP159526 | NCAPH2 | 29781 | RNAseq | 0.7586 | 0.0003 | |
| SRP193095 | NCAPH2 | 29781 | RNAseq | 0.6575 | 0.0000 | |
| SRP219564 | NCAPH2 | 29781 | RNAseq | 0.8906 | 0.0541 | |
| TCGA | NCAPH2 | 29781 | RNAseq | 0.1743 | 0.0016 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NCAPH2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NCAPH2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NCAPH2 | 29781 | 3 | 8 | 19 | |
| GSE20123 | NCAPH2 | 29781 | 3 | 8 | 19 | |
| GSE43470 | NCAPH2 | 29781 | 2 | 8 | 33 | |
| GSE46452 | NCAPH2 | 29781 | 31 | 2 | 26 | |
| GSE47630 | NCAPH2 | 29781 | 9 | 4 | 27 | |
| GSE54993 | NCAPH2 | 29781 | 4 | 6 | 60 | |
| GSE54994 | NCAPH2 | 29781 | 11 | 8 | 34 | |
| GSE60625 | NCAPH2 | 29781 | 5 | 0 | 6 | |
| GSE74703 | NCAPH2 | 29781 | 2 | 6 | 28 | |
| GSE74704 | NCAPH2 | 29781 | 1 | 4 | 15 | |
| TCGA | NCAPH2 | 29781 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of NCAPH2:
Generating mutation plots.
Highly correlated genes for NCAPH2:
Showing top 20/849 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NCAPH2 | LSM10 | 0.764761 | 3 | 0 | 3 |
| NCAPH2 | TMEM54 | 0.740176 | 4 | 0 | 4 |
| NCAPH2 | PEX10 | 0.721128 | 3 | 0 | 3 |
| NCAPH2 | UCN | 0.709545 | 3 | 0 | 3 |
| NCAPH2 | ELOF1 | 0.704905 | 3 | 0 | 3 |
| NCAPH2 | ALG1 | 0.702037 | 3 | 0 | 3 |
| NCAPH2 | SH2B2 | 0.692802 | 3 | 0 | 3 |
| NCAPH2 | MED24 | 0.691799 | 4 | 0 | 4 |
| NCAPH2 | CDH24 | 0.686601 | 3 | 0 | 3 |
| NCAPH2 | POLRMT | 0.685198 | 3 | 0 | 3 |
| NCAPH2 | SARS2 | 0.684598 | 3 | 0 | 3 |
| NCAPH2 | SIVA1 | 0.683366 | 10 | 0 | 10 |
| NCAPH2 | CMTM4 | 0.682162 | 3 | 0 | 3 |
| NCAPH2 | NKX6-2 | 0.681962 | 3 | 0 | 3 |
| NCAPH2 | SOX18 | 0.681611 | 3 | 0 | 3 |
| NCAPH2 | TP53I13 | 0.680067 | 6 | 0 | 5 |
| NCAPH2 | SORD | 0.677447 | 3 | 0 | 3 |
| NCAPH2 | VEZT | 0.677365 | 3 | 0 | 3 |
| NCAPH2 | CNTF | 0.676754 | 3 | 0 | 3 |
| NCAPH2 | ZCCHC17 | 0.676523 | 3 | 0 | 3 |
For details and further investigation, click here
