| Full name: NADH:ubiquinone oxidoreductase subunit S6 | Alias Symbol: CI-13kA | ||
| Type: protein-coding gene | Cytoband: 5p15.33 | ||
| Entrez ID: 4726 | HGNC ID: HGNC:7713 | Ensembl Gene: ENSG00000145494 | OMIM ID: 603848 |
| Drug and gene relationship at DGIdb | |||
Expression of NDUFS6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NDUFS6 | 4726 | 203606_at | 0.4436 | 0.1165 | |
| GSE20347 | NDUFS6 | 4726 | 203606_at | 0.2934 | 0.0126 | |
| GSE23400 | NDUFS6 | 4726 | 203606_at | 0.3655 | 0.0000 | |
| GSE26886 | NDUFS6 | 4726 | 203606_at | 0.3074 | 0.0269 | |
| GSE29001 | NDUFS6 | 4726 | 203606_at | 0.1960 | 0.5128 | |
| GSE38129 | NDUFS6 | 4726 | 203606_at | 0.3835 | 0.0001 | |
| GSE45670 | NDUFS6 | 4726 | 203606_at | 0.3801 | 0.0027 | |
| GSE53622 | NDUFS6 | 4726 | 54939 | 0.2182 | 0.0005 | |
| GSE53624 | NDUFS6 | 4726 | 54939 | 0.5026 | 0.0000 | |
| GSE63941 | NDUFS6 | 4726 | 203606_at | 0.6757 | 0.1256 | |
| GSE77861 | NDUFS6 | 4726 | 203606_at | 0.3729 | 0.0457 | |
| GSE97050 | NDUFS6 | 4726 | A_23_P122228 | 0.2462 | 0.2782 | |
| SRP007169 | NDUFS6 | 4726 | RNAseq | 0.1739 | 0.7218 | |
| SRP008496 | NDUFS6 | 4726 | RNAseq | -0.1460 | 0.6346 | |
| SRP064894 | NDUFS6 | 4726 | RNAseq | 0.3512 | 0.3575 | |
| SRP133303 | NDUFS6 | 4726 | RNAseq | 0.6202 | 0.0111 | |
| SRP159526 | NDUFS6 | 4726 | RNAseq | 0.8827 | 0.0046 | |
| SRP193095 | NDUFS6 | 4726 | RNAseq | 0.0022 | 0.9899 | |
| SRP219564 | NDUFS6 | 4726 | RNAseq | 0.3507 | 0.3833 | |
| TCGA | NDUFS6 | 4726 | RNAseq | 0.2142 | 0.0024 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NDUFS6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NDUFS6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NDUFS6 | 4726 | 13 | 1 | 16 | |
| GSE20123 | NDUFS6 | 4726 | 13 | 1 | 16 | |
| GSE43470 | NDUFS6 | 4726 | 17 | 1 | 25 | |
| GSE46452 | NDUFS6 | 4726 | 6 | 22 | 31 | |
| GSE47630 | NDUFS6 | 4726 | 6 | 11 | 23 | |
| GSE54993 | NDUFS6 | 4726 | 5 | 5 | 60 | |
| GSE54994 | NDUFS6 | 4726 | 29 | 1 | 23 | |
| GSE60625 | NDUFS6 | 4726 | 0 | 0 | 11 | |
| GSE74703 | NDUFS6 | 4726 | 14 | 0 | 22 | |
| GSE74704 | NDUFS6 | 4726 | 11 | 0 | 9 | |
| TCGA | NDUFS6 | 4726 | 59 | 3 | 34 |
Total number of gains: 173; Total number of losses: 45; Total Number of normals: 270.
Somatic mutations of NDUFS6:
Generating mutation plots.
Highly correlated genes for NDUFS6:
Showing top 20/979 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NDUFS6 | MRPL36 | 0.756349 | 8 | 0 | 8 |
| NDUFS6 | LILRB2 | 0.749179 | 3 | 0 | 3 |
| NDUFS6 | MRPS5 | 0.734037 | 3 | 0 | 3 |
| NDUFS6 | OTULIN | 0.729592 | 3 | 0 | 3 |
| NDUFS6 | UCKL1 | 0.72718 | 3 | 0 | 3 |
| NDUFS6 | TATDN1 | 0.726217 | 4 | 0 | 4 |
| NDUFS6 | TMEM63B | 0.720803 | 4 | 0 | 4 |
| NDUFS6 | MSTO1 | 0.711817 | 4 | 0 | 4 |
| NDUFS6 | TNFAIP1 | 0.710657 | 3 | 0 | 3 |
| NDUFS6 | NFKB2 | 0.707658 | 4 | 0 | 3 |
| NDUFS6 | NUS1 | 0.703756 | 5 | 0 | 5 |
| NDUFS6 | DDX21 | 0.701873 | 3 | 0 | 3 |
| NDUFS6 | PVR | 0.70108 | 3 | 0 | 3 |
| NDUFS6 | GRAMD4 | 0.699815 | 3 | 0 | 3 |
| NDUFS6 | DEPDC5 | 0.697653 | 3 | 0 | 3 |
| NDUFS6 | CHORDC1 | 0.697094 | 3 | 0 | 3 |
| NDUFS6 | TM9SF1 | 0.696856 | 4 | 0 | 3 |
| NDUFS6 | CDH24 | 0.695844 | 4 | 0 | 3 |
| NDUFS6 | ZFYVE27 | 0.695078 | 3 | 0 | 3 |
| NDUFS6 | VAPB | 0.692422 | 3 | 0 | 3 |
For details and further investigation, click here
