| Full name: neural precursor cell expressed, developmentally down-regulated 9 | Alias Symbol: HEF1|CAS-L|CASS2 | ||
| Type: protein-coding gene | Cytoband: 6p24.2 | ||
| Entrez ID: 4739 | HGNC ID: HGNC:7733 | Ensembl Gene: ENSG00000111859 | OMIM ID: 602265 |
| Drug and gene relationship at DGIdb | |||
Expression of NEDD9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NEDD9 | 4739 | 202149_at | -0.1922 | 0.8755 | |
| GSE20347 | NEDD9 | 4739 | 202149_at | 1.0338 | 0.0090 | |
| GSE23400 | NEDD9 | 4739 | 202150_s_at | 0.2559 | 0.0022 | |
| GSE26886 | NEDD9 | 4739 | 202149_at | 2.7420 | 0.0000 | |
| GSE29001 | NEDD9 | 4739 | 202149_at | 0.7583 | 0.1424 | |
| GSE38129 | NEDD9 | 4739 | 202149_at | 0.7690 | 0.0220 | |
| GSE45670 | NEDD9 | 4739 | 202149_at | -0.6332 | 0.2200 | |
| GSE53622 | NEDD9 | 4739 | 32048 | 0.4677 | 0.0024 | |
| GSE53624 | NEDD9 | 4739 | 32048 | 0.3315 | 0.0634 | |
| GSE63941 | NEDD9 | 4739 | 202149_at | 1.0175 | 0.4157 | |
| GSE77861 | NEDD9 | 4739 | 202150_s_at | 0.6214 | 0.0886 | |
| GSE97050 | NEDD9 | 4739 | A_23_P344555 | 0.4924 | 0.1403 | |
| SRP007169 | NEDD9 | 4739 | RNAseq | 2.7472 | 0.0000 | |
| SRP008496 | NEDD9 | 4739 | RNAseq | 2.5994 | 0.0000 | |
| SRP064894 | NEDD9 | 4739 | RNAseq | 0.7323 | 0.0142 | |
| SRP133303 | NEDD9 | 4739 | RNAseq | 0.7662 | 0.0047 | |
| SRP159526 | NEDD9 | 4739 | RNAseq | 1.5612 | 0.0000 | |
| SRP193095 | NEDD9 | 4739 | RNAseq | 0.7923 | 0.0165 | |
| SRP219564 | NEDD9 | 4739 | RNAseq | 0.8588 | 0.2237 | |
| TCGA | NEDD9 | 4739 | RNAseq | -0.1839 | 0.1096 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by NEDD9 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NEDD9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NEDD9 | 4739 | 4 | 7 | 19 | |
| GSE20123 | NEDD9 | 4739 | 4 | 7 | 19 | |
| GSE43470 | NEDD9 | 4739 | 9 | 1 | 33 | |
| GSE46452 | NEDD9 | 4739 | 1 | 10 | 48 | |
| GSE47630 | NEDD9 | 4739 | 7 | 8 | 25 | |
| GSE54993 | NEDD9 | 4739 | 1 | 1 | 68 | |
| GSE54994 | NEDD9 | 4739 | 10 | 3 | 40 | |
| GSE60625 | NEDD9 | 4739 | 0 | 1 | 10 | |
| GSE74703 | NEDD9 | 4739 | 8 | 1 | 27 | |
| GSE74704 | NEDD9 | 4739 | 2 | 3 | 15 | |
| TCGA | NEDD9 | 4739 | 15 | 28 | 53 |
Total number of gains: 61; Total number of losses: 70; Total Number of normals: 357.
Somatic mutations of NEDD9:
Generating mutation plots.
Highly correlated genes for NEDD9:
Showing top 20/1030 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NEDD9 | TMED8 | 0.796681 | 3 | 0 | 3 |
| NEDD9 | CXCL5 | 0.781743 | 3 | 0 | 3 |
| NEDD9 | DNM1L | 0.781518 | 3 | 0 | 3 |
| NEDD9 | BBS7 | 0.752515 | 3 | 0 | 3 |
| NEDD9 | TNFAIP8L2 | 0.747686 | 3 | 0 | 3 |
| NEDD9 | OCIAD2 | 0.745322 | 3 | 0 | 3 |
| NEDD9 | DOCK11 | 0.742973 | 4 | 0 | 4 |
| NEDD9 | TP53I13 | 0.74179 | 3 | 0 | 3 |
| NEDD9 | WDR81 | 0.738025 | 3 | 0 | 3 |
| NEDD9 | CSGALNACT1 | 0.729882 | 5 | 0 | 5 |
| NEDD9 | HCLS1 | 0.729477 | 3 | 0 | 3 |
| NEDD9 | STAT2 | 0.722202 | 3 | 0 | 3 |
| NEDD9 | RAMP2 | 0.719773 | 3 | 0 | 3 |
| NEDD9 | GPR158 | 0.719562 | 3 | 0 | 3 |
| NEDD9 | CLPTM1L | 0.718961 | 3 | 0 | 3 |
| NEDD9 | KIAA1586 | 0.718054 | 4 | 0 | 4 |
| NEDD9 | CD180 | 0.71509 | 3 | 0 | 3 |
| NEDD9 | ACSS3 | 0.712189 | 3 | 0 | 3 |
| NEDD9 | FMR1 | 0.710018 | 4 | 0 | 3 |
| NEDD9 | SLC38A10 | 0.709332 | 4 | 0 | 3 |
For details and further investigation, click here
