| Full name: Bardet-Biedl syndrome 7 | Alias Symbol: FLJ10715|BBS2L1 | ||
| Type: protein-coding gene | Cytoband: 4q27 | ||
| Entrez ID: 55212 | HGNC ID: HGNC:18758 | Ensembl Gene: ENSG00000138686 | OMIM ID: 607590 |
| Drug and gene relationship at DGIdb | |||
Expression of BBS7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | BBS7 | 55212 | 235007_at | -0.1118 | 0.8687 | |
| GSE20347 | BBS7 | 55212 | 219688_at | 0.1166 | 0.4821 | |
| GSE23400 | BBS7 | 55212 | 219688_at | 0.0358 | 0.1196 | |
| GSE26886 | BBS7 | 55212 | 235007_at | 0.4444 | 0.1788 | |
| GSE29001 | BBS7 | 55212 | 219688_at | 0.0295 | 0.9257 | |
| GSE38129 | BBS7 | 55212 | 219688_at | 0.2217 | 0.0703 | |
| GSE45670 | BBS7 | 55212 | 235007_at | -0.6639 | 0.0028 | |
| GSE53622 | BBS7 | 55212 | 91194 | -0.0645 | 0.5613 | |
| GSE53624 | BBS7 | 55212 | 91194 | 0.0830 | 0.3694 | |
| GSE63941 | BBS7 | 55212 | 235007_at | -1.5317 | 0.0129 | |
| GSE77861 | BBS7 | 55212 | 235007_at | 0.1847 | 0.5020 | |
| GSE97050 | BBS7 | 55212 | A_23_P252913 | 0.0005 | 0.9987 | |
| SRP007169 | BBS7 | 55212 | RNAseq | 0.3493 | 0.3888 | |
| SRP008496 | BBS7 | 55212 | RNAseq | 0.1855 | 0.5705 | |
| SRP064894 | BBS7 | 55212 | RNAseq | 0.1047 | 0.5709 | |
| SRP133303 | BBS7 | 55212 | RNAseq | 0.2502 | 0.1784 | |
| SRP159526 | BBS7 | 55212 | RNAseq | -0.2729 | 0.2296 | |
| SRP193095 | BBS7 | 55212 | RNAseq | -0.0263 | 0.7891 | |
| SRP219564 | BBS7 | 55212 | RNAseq | -0.4838 | 0.1501 | |
| TCGA | BBS7 | 55212 | RNAseq | 0.0085 | 0.8894 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by BBS7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of BBS7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | BBS7 | 55212 | 1 | 13 | 16 | |
| GSE20123 | BBS7 | 55212 | 1 | 13 | 16 | |
| GSE43470 | BBS7 | 55212 | 0 | 13 | 30 | |
| GSE46452 | BBS7 | 55212 | 1 | 36 | 22 | |
| GSE47630 | BBS7 | 55212 | 0 | 22 | 18 | |
| GSE54993 | BBS7 | 55212 | 9 | 0 | 61 | |
| GSE54994 | BBS7 | 55212 | 1 | 10 | 42 | |
| GSE60625 | BBS7 | 55212 | 0 | 1 | 10 | |
| GSE74703 | BBS7 | 55212 | 0 | 11 | 25 | |
| GSE74704 | BBS7 | 55212 | 0 | 7 | 13 | |
| TCGA | BBS7 | 55212 | 8 | 34 | 54 |
Total number of gains: 21; Total number of losses: 160; Total Number of normals: 307.
Somatic mutations of BBS7:
Generating mutation plots.
Highly correlated genes for BBS7:
Showing top 20/639 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| BBS7 | TUBGCP3 | 0.787802 | 3 | 0 | 3 |
| BBS7 | DMTF1 | 0.77148 | 4 | 0 | 4 |
| BBS7 | PIK3C3 | 0.765734 | 3 | 0 | 3 |
| BBS7 | CDKL3 | 0.758979 | 3 | 0 | 3 |
| BBS7 | RBM7 | 0.757945 | 3 | 0 | 3 |
| BBS7 | NFKB1 | 0.754921 | 3 | 0 | 3 |
| BBS7 | NEDD9 | 0.752515 | 3 | 0 | 3 |
| BBS7 | ZNF451 | 0.749775 | 3 | 0 | 3 |
| BBS7 | RBM18 | 0.741384 | 3 | 0 | 3 |
| BBS7 | SGMS1 | 0.738872 | 3 | 0 | 3 |
| BBS7 | RSRC2 | 0.736808 | 5 | 0 | 4 |
| BBS7 | PNPLA8 | 0.733541 | 3 | 0 | 3 |
| BBS7 | MCFD2 | 0.728105 | 3 | 0 | 3 |
| BBS7 | GNG2 | 0.727152 | 3 | 0 | 3 |
| BBS7 | CWF19L2 | 0.726566 | 4 | 0 | 3 |
| BBS7 | SMCHD1 | 0.716211 | 3 | 0 | 3 |
| BBS7 | ZBTB26 | 0.714504 | 3 | 0 | 3 |
| BBS7 | GYPC | 0.712957 | 3 | 0 | 3 |
| BBS7 | ASPA | 0.71284 | 3 | 0 | 3 |
| BBS7 | ARHGAP31 | 0.711896 | 3 | 0 | 3 |
For details and further investigation, click here
