| Full name: CD180 molecule | Alias Symbol: RP105|Ly78 | ||
| Type: protein-coding gene | Cytoband: 5q12.3 | ||
| Entrez ID: 4064 | HGNC ID: HGNC:6726 | Ensembl Gene: ENSG00000134061 | OMIM ID: 602226 |
| Drug and gene relationship at DGIdb | |||
Expression of CD180:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CD180 | 4064 | 206206_at | 0.1956 | 0.7858 | |
| GSE20347 | CD180 | 4064 | 206206_at | 0.0724 | 0.4840 | |
| GSE23400 | CD180 | 4064 | 206206_at | -0.0131 | 0.7636 | |
| GSE26886 | CD180 | 4064 | 206206_at | 0.0434 | 0.7821 | |
| GSE29001 | CD180 | 4064 | 206206_at | 0.1334 | 0.4580 | |
| GSE38129 | CD180 | 4064 | 206206_at | 0.0702 | 0.6472 | |
| GSE45670 | CD180 | 4064 | 206206_at | 0.2115 | 0.1510 | |
| GSE53622 | CD180 | 4064 | 17538 | 0.4267 | 0.1487 | |
| GSE53624 | CD180 | 4064 | 17538 | 0.1962 | 0.5145 | |
| GSE63941 | CD180 | 4064 | 206206_at | -0.0002 | 0.9988 | |
| GSE77861 | CD180 | 4064 | 206206_at | 0.0438 | 0.6790 | |
| GSE97050 | CD180 | 4064 | A_23_P257815 | 0.2308 | 0.3375 | |
| SRP007169 | CD180 | 4064 | RNAseq | 2.7617 | 0.0007 | |
| SRP008496 | CD180 | 4064 | RNAseq | 2.9005 | 0.0001 | |
| SRP064894 | CD180 | 4064 | RNAseq | 1.2979 | 0.0000 | |
| SRP133303 | CD180 | 4064 | RNAseq | 0.1293 | 0.5650 | |
| SRP159526 | CD180 | 4064 | RNAseq | -0.1545 | 0.8658 | |
| SRP193095 | CD180 | 4064 | RNAseq | 0.1575 | 0.4702 | |
| SRP219564 | CD180 | 4064 | RNAseq | 1.0803 | 0.0347 | |
| TCGA | CD180 | 4064 | RNAseq | -0.0749 | 0.7260 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by CD180 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CD180:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CD180 | 4064 | 0 | 13 | 17 | |
| GSE20123 | CD180 | 4064 | 0 | 13 | 17 | |
| GSE43470 | CD180 | 4064 | 1 | 12 | 30 | |
| GSE46452 | CD180 | 4064 | 0 | 28 | 31 | |
| GSE47630 | CD180 | 4064 | 2 | 17 | 21 | |
| GSE54993 | CD180 | 4064 | 8 | 1 | 61 | |
| GSE54994 | CD180 | 4064 | 1 | 19 | 33 | |
| GSE60625 | CD180 | 4064 | 0 | 0 | 11 | |
| GSE74703 | CD180 | 4064 | 1 | 9 | 26 | |
| GSE74704 | CD180 | 4064 | 0 | 6 | 14 | |
| TCGA | CD180 | 4064 | 4 | 50 | 42 |
Total number of gains: 17; Total number of losses: 168; Total Number of normals: 303.
Somatic mutations of CD180:
Generating mutation plots.
Highly correlated genes for CD180:
Showing top 20/837 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CD180 | PIK3AP1 | 0.807095 | 4 | 0 | 4 |
| CD180 | TTYH2 | 0.764308 | 3 | 0 | 3 |
| CD180 | BTLA | 0.76406 | 5 | 0 | 5 |
| CD180 | C1orf162 | 0.759275 | 4 | 0 | 4 |
| CD180 | GZMK | 0.747698 | 4 | 0 | 4 |
| CD180 | CD79B | 0.746499 | 7 | 0 | 7 |
| CD180 | FXR2 | 0.743908 | 3 | 0 | 3 |
| CD180 | CRYBA1 | 0.740414 | 3 | 0 | 3 |
| CD180 | VCP | 0.736008 | 3 | 0 | 3 |
| CD180 | GPR34 | 0.732338 | 5 | 0 | 5 |
| CD180 | CERKL | 0.730554 | 3 | 0 | 3 |
| CD180 | IRF8 | 0.729936 | 7 | 0 | 6 |
| CD180 | POU2AF1 | 0.727268 | 3 | 0 | 3 |
| CD180 | ICAM5 | 0.726448 | 3 | 0 | 3 |
| CD180 | ITGAM | 0.724325 | 5 | 0 | 5 |
| CD180 | ARHGAP9 | 0.724167 | 5 | 0 | 5 |
| CD180 | GPR65 | 0.721788 | 6 | 0 | 4 |
| CD180 | ZC3H7B | 0.719845 | 3 | 0 | 3 |
| CD180 | PIM2 | 0.718531 | 6 | 0 | 6 |
| CD180 | GIMAP5 | 0.716413 | 3 | 0 | 3 |
For details and further investigation, click here
