KCNC2

 

Full name: potassium voltage-gated channel subfamily C member 2 Alias Symbol: Kv3.2
Type: protein-coding gene Cytoband: 12q21.1
Entrez ID: 3747 HGNC ID: HGNC:6234 Ensembl Gene: ENSG00000166006 OMIM ID: 176256
Drug and gene relationship at DGIdb

 

Expression of KCNC2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KCNC2 3747 222289_at -0.0143 0.9514
GSE20347 KCNC2 3747 222289_at -0.0469 0.5113
GSE23400 KCNC2 3747 222289_at -0.0495 0.0599
GSE26886 KCNC2 3747 222289_at 0.2683 0.0090
GSE29001 KCNC2 3747 222289_at 0.0055 0.9648
GSE38129 KCNC2 3747 222289_at -0.1165 0.0903
GSE45670 KCNC2 3747 222289_at -0.0950 0.2790
GSE53622 KCNC2 3747 112718 -0.0430 0.8238
GSE53624 KCNC2 3747 112718 0.0462 0.7008
GSE63941 KCNC2 3747 222289_at 0.1911 0.1504
GSE77861 KCNC2 3747 222289_at 0.0069 0.9647

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by KCNC2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of KCNC2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KCNC2 3747 3 3 24
GSE20123 KCNC2 3747 3 3 24
GSE43470 KCNC2 3747 3 0 40
GSE46452 KCNC2 3747 8 1 50
GSE47630 KCNC2 3747 10 1 29
GSE54993 KCNC2 3747 0 5 65
GSE54994 KCNC2 3747 5 2 46
GSE60625 KCNC2 3747 0 0 11
GSE74703 KCNC2 3747 3 0 33
GSE74704 KCNC2 3747 2 2 16
TCGA KCNC2 3747 16 15 65

Total number of gains: 53; Total number of losses: 32; Total Number of normals: 403.  


 

Somatic mutations of KCNC2:

 

Generating mutation plots.

 

Highly correlated genes for KCNC2:

 

Showing top 20/485 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KCNC2CACNA1H0.736427303
KCNC2SLC6A30.688887303
KCNC2LINGO10.685905303
KCNC2CPT1C0.683508303
KCNC2STK32C0.675247303
KCNC2HDAC70.672108303
KCNC2HDAC110.670792303
KCNC2LINC005980.667645303
KCNC2JSRP10.667173403
KCNC2SARDH0.665235403
KCNC2DSCAML10.660017303
KCNC2SELPLG0.657575403
KCNC2LTB4R20.655059605
KCNC2HGD0.65415605
KCNC2MYOG0.653903707
KCNC2KIF190.650485303
KCNC2TCF150.650297504
KCNC2PLD40.645085303
KCNC2SIX60.644714605
KCNC2IGFALS0.642397806

For details and further investigation, click here