| Full name: apolipoprotein C2 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19q13.32 | ||
| Entrez ID: 344 | HGNC ID: HGNC:609 | Ensembl Gene: ENSG00000234906 | OMIM ID: 608083 |
| Drug and gene relationship at DGIdb | |||
Expression of APOC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | APOC2 | 344 | 231561_s_at | 0.0987 | 0.7103 | |
| GSE26886 | APOC2 | 344 | 231561_s_at | 0.4064 | 0.0028 | |
| GSE45670 | APOC2 | 344 | 231561_s_at | -0.2015 | 0.0409 | |
| GSE63941 | APOC2 | 344 | 231561_s_at | 0.0605 | 0.7047 | |
| GSE77861 | APOC2 | 344 | 231561_s_at | -0.1322 | 0.4292 | |
| SRP133303 | APOC2 | 344 | RNAseq | 3.4732 | 0.0000 | |
| SRP159526 | APOC2 | 344 | RNAseq | 0.8913 | 0.2336 | |
| SRP219564 | APOC2 | 344 | RNAseq | 2.4682 | 0.0029 | |
| TCGA | APOC2 | 344 | RNAseq | 3.1252 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by APOC2 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of APOC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | APOC2 | 344 | 4 | 5 | 21 | |
| GSE20123 | APOC2 | 344 | 4 | 4 | 22 | |
| GSE43470 | APOC2 | 344 | 3 | 11 | 29 | |
| GSE46452 | APOC2 | 344 | 45 | 1 | 13 | |
| GSE47630 | APOC2 | 344 | 8 | 6 | 26 | |
| GSE54993 | APOC2 | 344 | 17 | 4 | 49 | |
| GSE54994 | APOC2 | 344 | 6 | 12 | 35 | |
| GSE60625 | APOC2 | 344 | 9 | 0 | 2 | |
| GSE74703 | APOC2 | 344 | 3 | 7 | 26 | |
| GSE74704 | APOC2 | 344 | 4 | 2 | 14 | |
| TCGA | APOC2 | 344 | 14 | 17 | 65 |
Total number of gains: 117; Total number of losses: 69; Total Number of normals: 302.
Somatic mutations of APOC2:
Generating mutation plots.
Highly correlated genes for APOC2:
Showing top 20/109 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| APOC2 | ACHE | 0.785635 | 3 | 0 | 3 |
| APOC2 | ZBED3-AS1 | 0.750899 | 3 | 0 | 3 |
| APOC2 | NOXA1 | 0.732732 | 3 | 0 | 3 |
| APOC2 | ENTPD2 | 0.729398 | 3 | 0 | 3 |
| APOC2 | STK32C | 0.728411 | 3 | 0 | 3 |
| APOC2 | CNIH2 | 0.725739 | 3 | 0 | 3 |
| APOC2 | FUT7 | 0.725118 | 3 | 0 | 3 |
| APOC2 | TRMT61A | 0.724134 | 3 | 0 | 3 |
| APOC2 | PKLR | 0.707773 | 3 | 0 | 3 |
| APOC2 | GPC2 | 0.703772 | 3 | 0 | 3 |
| APOC2 | LTB4R2 | 0.703337 | 3 | 0 | 3 |
| APOC2 | NEU4 | 0.698448 | 3 | 0 | 3 |
| APOC2 | IQCC | 0.696475 | 4 | 0 | 3 |
| APOC2 | IBSP | 0.694055 | 3 | 0 | 3 |
| APOC2 | BIRC7 | 0.690958 | 3 | 0 | 3 |
| APOC2 | SLC25A29 | 0.690301 | 3 | 0 | 3 |
| APOC2 | GNL1 | 0.681074 | 3 | 0 | 3 |
| APOC2 | CPAMD8 | 0.678244 | 3 | 0 | 3 |
| APOC2 | HMCN2 | 0.674019 | 3 | 0 | 3 |
| APOC2 | PTP4A3 | 0.669758 | 4 | 0 | 3 |
For details and further investigation, click here
