| Full name: sulfotransferase family 2A member 1 | Alias Symbol: DHEA-ST | ||
| Type: protein-coding gene | Cytoband: 19q13.33 | ||
| Entrez ID: 6822 | HGNC ID: HGNC:11458 | Ensembl Gene: ENSG00000105398 | OMIM ID: 125263 |
| Drug and gene relationship at DGIdb | |||
Expression of SULT2A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SULT2A1 | 6822 | 206292_s_at | 0.0582 | 0.7864 | |
| GSE20347 | SULT2A1 | 6822 | 206292_s_at | -0.0151 | 0.8402 | |
| GSE23400 | SULT2A1 | 6822 | 206292_s_at | -0.0959 | 0.0050 | |
| GSE26886 | SULT2A1 | 6822 | 206292_s_at | 0.0881 | 0.4044 | |
| GSE29001 | SULT2A1 | 6822 | 206292_s_at | -0.0789 | 0.5358 | |
| GSE38129 | SULT2A1 | 6822 | 206292_s_at | -0.2659 | 0.1212 | |
| GSE45670 | SULT2A1 | 6822 | 206292_s_at | 0.0219 | 0.8294 | |
| GSE53622 | SULT2A1 | 6822 | 26151 | -2.2655 | 0.0000 | |
| GSE53624 | SULT2A1 | 6822 | 26151 | -1.6216 | 0.0000 | |
| GSE63941 | SULT2A1 | 6822 | 206292_s_at | 0.2090 | 0.6433 | |
| GSE77861 | SULT2A1 | 6822 | 206292_s_at | -0.1180 | 0.1944 | |
| SRP133303 | SULT2A1 | 6822 | RNAseq | -0.0698 | 0.8107 | |
| TCGA | SULT2A1 | 6822 | RNAseq | -6.2270 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by SULT2A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SULT2A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SULT2A1 | 6822 | 4 | 4 | 22 | |
| GSE20123 | SULT2A1 | 6822 | 4 | 3 | 23 | |
| GSE43470 | SULT2A1 | 6822 | 3 | 10 | 30 | |
| GSE46452 | SULT2A1 | 6822 | 45 | 1 | 13 | |
| GSE47630 | SULT2A1 | 6822 | 8 | 7 | 25 | |
| GSE54993 | SULT2A1 | 6822 | 17 | 4 | 49 | |
| GSE54994 | SULT2A1 | 6822 | 4 | 14 | 35 | |
| GSE60625 | SULT2A1 | 6822 | 9 | 0 | 2 | |
| GSE74703 | SULT2A1 | 6822 | 3 | 7 | 26 | |
| GSE74704 | SULT2A1 | 6822 | 4 | 1 | 15 | |
| TCGA | SULT2A1 | 6822 | 15 | 18 | 63 |
Total number of gains: 116; Total number of losses: 69; Total Number of normals: 303.
Somatic mutations of SULT2A1:
Generating mutation plots.
Highly correlated genes for SULT2A1:
Showing top 20/425 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SULT2A1 | TAS2R3 | 0.748721 | 3 | 0 | 3 |
| SULT2A1 | RIT2 | 0.723677 | 3 | 0 | 3 |
| SULT2A1 | OR10H3 | 0.717159 | 3 | 0 | 3 |
| SULT2A1 | KIR2DS2 | 0.71527 | 3 | 0 | 3 |
| SULT2A1 | MBTPS2 | 0.712126 | 3 | 0 | 3 |
| SULT2A1 | OR7C2 | 0.708519 | 3 | 0 | 3 |
| SULT2A1 | FOLH1 | 0.704871 | 3 | 0 | 3 |
| SULT2A1 | LALBA | 0.699146 | 3 | 0 | 3 |
| SULT2A1 | CA8 | 0.698183 | 3 | 0 | 3 |
| SULT2A1 | SMCP | 0.696767 | 3 | 0 | 3 |
| SULT2A1 | CHRM2 | 0.685934 | 3 | 0 | 3 |
| SULT2A1 | SLC10A1 | 0.679844 | 3 | 0 | 3 |
| SULT2A1 | G6PC2 | 0.678786 | 4 | 0 | 4 |
| SULT2A1 | ARPP21 | 0.678171 | 3 | 0 | 3 |
| SULT2A1 | NEUROD1 | 0.677499 | 4 | 0 | 3 |
| SULT2A1 | GPC5 | 0.671269 | 5 | 0 | 5 |
| SULT2A1 | ACVR2B-AS1 | 0.664913 | 3 | 0 | 3 |
| SULT2A1 | MUC5AC | 0.664127 | 6 | 0 | 6 |
| SULT2A1 | TBX10 | 0.664105 | 3 | 0 | 3 |
| SULT2A1 | FRMPD1 | 0.661945 | 3 | 0 | 3 |
For details and further investigation, click here
