| Full name: cell division cycle 14A | Alias Symbol: Cdc14A1|Cdc14A2|cdc14|DFNB105 | ||
| Type: protein-coding gene | Cytoband: 1p21.2 | ||
| Entrez ID: 8556 | HGNC ID: HGNC:1718 | Ensembl Gene: ENSG00000079335 | OMIM ID: 603504 |
| Drug and gene relationship at DGIdb | |||
CDC14A involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04110 | Cell cycle |
Expression of CDC14A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CDC14A | 8556 | 210440_s_at | 0.0076 | 0.9883 | |
| GSE20347 | CDC14A | 8556 | 210440_s_at | -0.1704 | 0.0382 | |
| GSE23400 | CDC14A | 8556 | 210441_at | -0.1253 | 0.0004 | |
| GSE26886 | CDC14A | 8556 | 210440_s_at | -0.0808 | 0.4566 | |
| GSE29001 | CDC14A | 8556 | 210441_at | -0.1963 | 0.1590 | |
| GSE38129 | CDC14A | 8556 | 210440_s_at | -0.1901 | 0.0187 | |
| GSE45670 | CDC14A | 8556 | 210742_at | -0.1474 | 0.3819 | |
| GSE53622 | CDC14A | 8556 | 39580 | 0.0885 | 0.4313 | |
| GSE53624 | CDC14A | 8556 | 39580 | 0.4312 | 0.0002 | |
| GSE63941 | CDC14A | 8556 | 210440_s_at | 0.7952 | 0.0029 | |
| GSE77861 | CDC14A | 8556 | 210440_s_at | -0.1977 | 0.0771 | |
| GSE97050 | CDC14A | 8556 | A_23_P405110 | 0.2626 | 0.3998 | |
| SRP007169 | CDC14A | 8556 | RNAseq | 0.7229 | 0.1262 | |
| SRP008496 | CDC14A | 8556 | RNAseq | 0.7170 | 0.0643 | |
| SRP064894 | CDC14A | 8556 | RNAseq | 0.2440 | 0.3935 | |
| SRP133303 | CDC14A | 8556 | RNAseq | -0.0466 | 0.8385 | |
| SRP159526 | CDC14A | 8556 | RNAseq | -0.1347 | 0.7541 | |
| SRP193095 | CDC14A | 8556 | RNAseq | -0.0406 | 0.8365 | |
| SRP219564 | CDC14A | 8556 | RNAseq | -0.4971 | 0.3927 | |
| TCGA | CDC14A | 8556 | RNAseq | -0.3223 | 0.0020 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by CDC14A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CDC14A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CDC14A | 8556 | 0 | 10 | 20 | |
| GSE20123 | CDC14A | 8556 | 0 | 10 | 20 | |
| GSE43470 | CDC14A | 8556 | 2 | 6 | 35 | |
| GSE46452 | CDC14A | 8556 | 1 | 1 | 57 | |
| GSE47630 | CDC14A | 8556 | 9 | 5 | 26 | |
| GSE54993 | CDC14A | 8556 | 0 | 1 | 69 | |
| GSE54994 | CDC14A | 8556 | 6 | 3 | 44 | |
| GSE60625 | CDC14A | 8556 | 0 | 0 | 11 | |
| GSE74703 | CDC14A | 8556 | 1 | 5 | 30 | |
| GSE74704 | CDC14A | 8556 | 0 | 6 | 14 | |
| TCGA | CDC14A | 8556 | 8 | 25 | 63 |
Total number of gains: 27; Total number of losses: 72; Total Number of normals: 389.
Somatic mutations of CDC14A:
Generating mutation plots.
Highly correlated genes for CDC14A:
Showing top 20/668 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CDC14A | PWWP2A | 0.7769 | 3 | 0 | 3 |
| CDC14A | GIT1 | 0.766502 | 3 | 0 | 3 |
| CDC14A | COPE | 0.754813 | 3 | 0 | 3 |
| CDC14A | RFTN2 | 0.723613 | 3 | 0 | 3 |
| CDC14A | MAGEC2 | 0.723432 | 3 | 0 | 3 |
| CDC14A | HSPB6 | 0.720111 | 3 | 0 | 3 |
| CDC14A | ATF7 | 0.718804 | 4 | 0 | 4 |
| CDC14A | AKR7A2 | 0.717609 | 3 | 0 | 3 |
| CDC14A | FBXO16 | 0.70909 | 4 | 0 | 3 |
| CDC14A | USP5 | 0.707343 | 3 | 0 | 3 |
| CDC14A | UBASH3A | 0.70485 | 3 | 0 | 3 |
| CDC14A | CNOT1 | 0.704274 | 3 | 0 | 3 |
| CDC14A | ADAM11 | 0.699779 | 7 | 0 | 7 |
| CDC14A | PHLPP1 | 0.694568 | 3 | 0 | 3 |
| CDC14A | CRYBB2 | 0.690518 | 3 | 0 | 3 |
| CDC14A | CYGB | 0.690025 | 3 | 0 | 3 |
| CDC14A | CBL | 0.68841 | 5 | 0 | 4 |
| CDC14A | DNAH1 | 0.688045 | 4 | 0 | 4 |
| CDC14A | SOX13 | 0.687899 | 3 | 0 | 3 |
| CDC14A | GHDC | 0.686939 | 3 | 0 | 3 |
For details and further investigation, click here
