| Full name: NFKB inhibitor like 1 | Alias Symbol: IKBL | ||
| Type: protein-coding gene | Cytoband: 6p21.33 | ||
| Entrez ID: 4795 | HGNC ID: HGNC:7800 | Ensembl Gene: ENSG00000204498 | OMIM ID: 601022 |
| Drug and gene relationship at DGIdb | |||
Expression of NFKBIL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFKBIL1 | 4795 | 209973_at | 0.0221 | 0.9619 | |
| GSE20347 | NFKBIL1 | 4795 | 209973_at | -0.1057 | 0.1723 | |
| GSE23400 | NFKBIL1 | 4795 | 209973_at | -0.0810 | 0.0495 | |
| GSE26886 | NFKBIL1 | 4795 | 209973_at | 0.3439 | 0.0087 | |
| GSE29001 | NFKBIL1 | 4795 | 209973_at | -0.0718 | 0.7201 | |
| GSE38129 | NFKBIL1 | 4795 | 209973_at | -0.1041 | 0.2078 | |
| GSE45670 | NFKBIL1 | 4795 | 209973_at | -0.1429 | 0.0457 | |
| GSE53622 | NFKBIL1 | 4795 | 141739 | -0.1751 | 0.0001 | |
| GSE53624 | NFKBIL1 | 4795 | 141739 | 0.0139 | 0.7984 | |
| GSE63941 | NFKBIL1 | 4795 | 209973_at | 0.2239 | 0.3198 | |
| GSE77861 | NFKBIL1 | 4795 | 209973_at | -0.2981 | 0.0160 | |
| GSE97050 | NFKBIL1 | 4795 | A_33_P3386506 | 0.0298 | 0.8983 | |
| SRP007169 | NFKBIL1 | 4795 | RNAseq | -1.3031 | 0.0008 | |
| SRP008496 | NFKBIL1 | 4795 | RNAseq | -0.6136 | 0.0399 | |
| SRP064894 | NFKBIL1 | 4795 | RNAseq | 0.3890 | 0.2477 | |
| SRP133303 | NFKBIL1 | 4795 | RNAseq | 0.0171 | 0.9295 | |
| SRP159526 | NFKBIL1 | 4795 | RNAseq | 0.3402 | 0.1947 | |
| SRP193095 | NFKBIL1 | 4795 | RNAseq | 0.0501 | 0.6227 | |
| SRP219564 | NFKBIL1 | 4795 | RNAseq | -0.0104 | 0.9711 | |
| TCGA | NFKBIL1 | 4795 | RNAseq | -0.0857 | 0.1728 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NFKBIL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFKBIL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFKBIL1 | 4795 | 5 | 1 | 24 | |
| GSE20123 | NFKBIL1 | 4795 | 5 | 1 | 24 | |
| GSE43470 | NFKBIL1 | 4795 | 6 | 3 | 34 | |
| GSE46452 | NFKBIL1 | 4795 | 1 | 10 | 48 | |
| GSE47630 | NFKBIL1 | 4795 | 7 | 5 | 28 | |
| GSE54993 | NFKBIL1 | 4795 | 2 | 1 | 67 | |
| GSE54994 | NFKBIL1 | 4795 | 11 | 4 | 38 | |
| GSE60625 | NFKBIL1 | 4795 | 0 | 1 | 10 | |
| GSE74703 | NFKBIL1 | 4795 | 6 | 1 | 29 | |
| GSE74704 | NFKBIL1 | 4795 | 2 | 0 | 18 | |
| TCGA | NFKBIL1 | 4795 | 16 | 16 | 64 |
Total number of gains: 61; Total number of losses: 43; Total Number of normals: 384.
Somatic mutations of NFKBIL1:
Generating mutation plots.
Highly correlated genes for NFKBIL1:
Showing top 20/323 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFKBIL1 | PEPD | 0.76881 | 3 | 0 | 3 |
| NFKBIL1 | SND1 | 0.738686 | 3 | 0 | 3 |
| NFKBIL1 | INO80E | 0.726607 | 3 | 0 | 3 |
| NFKBIL1 | CDAN1 | 0.721137 | 3 | 0 | 3 |
| NFKBIL1 | ADCK1 | 0.711832 | 3 | 0 | 3 |
| NFKBIL1 | CCDC24 | 0.704275 | 3 | 0 | 3 |
| NFKBIL1 | PACSIN3 | 0.702488 | 4 | 0 | 4 |
| NFKBIL1 | COMTD1 | 0.697326 | 3 | 0 | 3 |
| NFKBIL1 | TMCO4 | 0.694763 | 3 | 0 | 3 |
| NFKBIL1 | C1orf122 | 0.687175 | 3 | 0 | 3 |
| NFKBIL1 | TRAF2 | 0.686132 | 3 | 0 | 3 |
| NFKBIL1 | PHF13 | 0.682824 | 4 | 0 | 4 |
| NFKBIL1 | SRGAP3 | 0.677516 | 3 | 0 | 3 |
| NFKBIL1 | SLC44A4 | 0.669194 | 3 | 0 | 3 |
| NFKBIL1 | TMEM219 | 0.669183 | 3 | 0 | 3 |
| NFKBIL1 | PNN | 0.667341 | 4 | 0 | 3 |
| NFKBIL1 | ANKRD65 | 0.666018 | 3 | 0 | 3 |
| NFKBIL1 | ZNF282 | 0.665109 | 3 | 0 | 3 |
| NFKBIL1 | SULT1C2 | 0.663379 | 3 | 0 | 3 |
| NFKBIL1 | ALKBH7 | 0.662551 | 4 | 0 | 3 |
For details and further investigation, click here
