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Multi-Omics Database of ESCC

 

NFKBIL1

 

Full name: NFKB inhibitor like 1 Alias Symbol: IKBL
Type: protein-coding gene Cytoband: 6p21.33
Entrez ID: 4795 HGNC ID: HGNC:7800 Ensembl Gene: ENSG00000204498 OMIM ID: 601022
Drug and gene relationship at DGIdb

 

Expression of NFKBIL1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NFKBIL1 4795 209973_at 0.0221 0.9619
GSE20347 NFKBIL1 4795 209973_at -0.1057 0.1723
GSE23400 NFKBIL1 4795 209973_at -0.0810 0.0495
GSE26886 NFKBIL1 4795 209973_at 0.3439 0.0087
GSE29001 NFKBIL1 4795 209973_at -0.0718 0.7201
GSE38129 NFKBIL1 4795 209973_at -0.1041 0.2078
GSE45670 NFKBIL1 4795 209973_at -0.1429 0.0457
GSE53622 NFKBIL1 4795 141739 -0.1751 0.0001
GSE53624 NFKBIL1 4795 141739 0.0139 0.7984
GSE63941 NFKBIL1 4795 209973_at 0.2239 0.3198
GSE77861 NFKBIL1 4795 209973_at -0.2981 0.0160
GSE97050 NFKBIL1 4795 A_33_P3386506 0.0298 0.8983
SRP007169 NFKBIL1 4795 RNAseq -1.3031 0.0008
SRP008496 NFKBIL1 4795 RNAseq -0.6136 0.0399
SRP064894 NFKBIL1 4795 RNAseq 0.3890 0.2477
SRP133303 NFKBIL1 4795 RNAseq 0.0171 0.9295
SRP159526 NFKBIL1 4795 RNAseq 0.3402 0.1947
SRP193095 NFKBIL1 4795 RNAseq 0.0501 0.6227
SRP219564 NFKBIL1 4795 RNAseq -0.0104 0.9711
TCGA NFKBIL1 4795 RNAseq -0.0857 0.1728

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by NFKBIL1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NFKBIL1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NFKBIL1 4795 5 1 24
GSE20123 NFKBIL1 4795 5 1 24
GSE43470 NFKBIL1 4795 6 3 34
GSE46452 NFKBIL1 4795 1 10 48
GSE47630 NFKBIL1 4795 7 5 28
GSE54993 NFKBIL1 4795 2 1 67
GSE54994 NFKBIL1 4795 11 4 38
GSE60625 NFKBIL1 4795 0 1 10
GSE74703 NFKBIL1 4795 6 1 29
GSE74704 NFKBIL1 4795 2 0 18
TCGA NFKBIL1 4795 16 16 64

Total number of gains: 61; Total number of losses: 43; Total Number of normals: 384.  

 

Somatic mutations of NFKBIL1:

 

Generating mutation plots.

 

Highly correlated genes for NFKBIL1:

 

Showing top 20/323 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NFKBIL1PEPD0.76881303
NFKBIL1SND10.738686303
NFKBIL1INO80E0.726607303
NFKBIL1CDAN10.721137303
NFKBIL1ADCK10.711832303
NFKBIL1CCDC240.704275303
NFKBIL1PACSIN30.702488404
NFKBIL1COMTD10.697326303
NFKBIL1TMCO40.694763303
NFKBIL1C1orf1220.687175303
NFKBIL1TRAF20.686132303
NFKBIL1PHF130.682824404
NFKBIL1SRGAP30.677516303
NFKBIL1SLC44A40.669194303
NFKBIL1TMEM2190.669183303
NFKBIL1PNN0.667341403
NFKBIL1ANKRD650.666018303
NFKBIL1ZNF2820.665109303
NFKBIL1SULT1C20.663379303
NFKBIL1ALKBH70.662551403

For details and further investigation, click here