| Full name: staphylococcal nuclease and tudor domain containing 1 | Alias Symbol: TDRD11|p100 | ||
| Type: protein-coding gene | Cytoband: 7q32.1 | ||
| Entrez ID: 27044 | HGNC ID: HGNC:30646 | Ensembl Gene: ENSG00000197157 | OMIM ID: 602181 |
| Drug and gene relationship at DGIdb | |||
Expression of SND1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SND1 | 27044 | 201622_at | 0.2640 | 0.4893 | |
| GSE20347 | SND1 | 27044 | 201622_at | 0.0916 | 0.3885 | |
| GSE23400 | SND1 | 27044 | 201622_at | 0.1289 | 0.0136 | |
| GSE26886 | SND1 | 27044 | 201622_at | 0.0823 | 0.5654 | |
| GSE29001 | SND1 | 27044 | 201622_at | 0.0290 | 0.9312 | |
| GSE38129 | SND1 | 27044 | 201622_at | 0.2222 | 0.0134 | |
| GSE45670 | SND1 | 27044 | 201622_at | 0.1076 | 0.4240 | |
| GSE53622 | SND1 | 27044 | 38566 | 0.0447 | 0.4783 | |
| GSE53624 | SND1 | 27044 | 38566 | 0.2077 | 0.0000 | |
| GSE63941 | SND1 | 27044 | 201622_at | -0.2360 | 0.4503 | |
| GSE77861 | SND1 | 27044 | 201622_at | 0.1762 | 0.2224 | |
| GSE97050 | SND1 | 27044 | A_23_P42829 | 0.3284 | 0.2333 | |
| SRP007169 | SND1 | 27044 | RNAseq | -0.1296 | 0.7285 | |
| SRP008496 | SND1 | 27044 | RNAseq | 0.0983 | 0.6999 | |
| SRP064894 | SND1 | 27044 | RNAseq | 0.3756 | 0.0037 | |
| SRP133303 | SND1 | 27044 | RNAseq | 0.3221 | 0.0274 | |
| SRP159526 | SND1 | 27044 | RNAseq | -0.1349 | 0.4270 | |
| SRP193095 | SND1 | 27044 | RNAseq | 0.0615 | 0.5310 | |
| SRP219564 | SND1 | 27044 | RNAseq | 0.2877 | 0.2410 | |
| TCGA | SND1 | 27044 | RNAseq | -0.0925 | 0.0416 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SND1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SND1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SND1 | 27044 | 7 | 1 | 22 | |
| GSE20123 | SND1 | 27044 | 7 | 2 | 21 | |
| GSE43470 | SND1 | 27044 | 2 | 3 | 38 | |
| GSE46452 | SND1 | 27044 | 7 | 2 | 50 | |
| GSE47630 | SND1 | 27044 | 7 | 4 | 29 | |
| GSE54993 | SND1 | 27044 | 3 | 5 | 62 | |
| GSE54994 | SND1 | 27044 | 9 | 7 | 37 | |
| GSE60625 | SND1 | 27044 | 0 | 0 | 11 | |
| GSE74703 | SND1 | 27044 | 2 | 3 | 31 | |
| GSE74704 | SND1 | 27044 | 3 | 2 | 15 | |
| TCGA | SND1 | 27044 | 30 | 23 | 43 |
Total number of gains: 77; Total number of losses: 52; Total Number of normals: 359.
Somatic mutations of SND1:
Generating mutation plots.
Highly correlated genes for SND1:
Showing top 20/495 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SND1 | LDLRAP1 | 0.8355 | 3 | 0 | 3 |
| SND1 | MPHOSPH9 | 0.792298 | 3 | 0 | 3 |
| SND1 | HIC2 | 0.780685 | 3 | 0 | 3 |
| SND1 | GLE1 | 0.775407 | 3 | 0 | 3 |
| SND1 | RSBN1L | 0.774708 | 3 | 0 | 3 |
| SND1 | ELOF1 | 0.766938 | 4 | 0 | 4 |
| SND1 | CLEC12A | 0.766795 | 3 | 0 | 3 |
| SND1 | KLHDC3 | 0.762475 | 3 | 0 | 3 |
| SND1 | SMAD1 | 0.752275 | 3 | 0 | 3 |
| SND1 | NFKBIL1 | 0.738686 | 3 | 0 | 3 |
| SND1 | SLC30A7 | 0.738493 | 3 | 0 | 3 |
| SND1 | KRTCAP2 | 0.738088 | 3 | 0 | 3 |
| SND1 | KCTD10 | 0.738065 | 3 | 0 | 3 |
| SND1 | PALB2 | 0.733488 | 3 | 0 | 3 |
| SND1 | UBE2J2 | 0.731646 | 3 | 0 | 3 |
| SND1 | DDX21 | 0.729018 | 3 | 0 | 3 |
| SND1 | PEX10 | 0.728185 | 3 | 0 | 3 |
| SND1 | SNAPC2 | 0.720259 | 3 | 0 | 3 |
| SND1 | APH1B | 0.718076 | 3 | 0 | 3 |
| SND1 | RUNDC1 | 0.716137 | 3 | 0 | 3 |
For details and further investigation, click here
