| Full name: zinc finger protein 282 | Alias Symbol: HUB1 | ||
| Type: protein-coding gene | Cytoband: 7q36.1 | ||
| Entrez ID: 8427 | HGNC ID: HGNC:13076 | Ensembl Gene: ENSG00000170265 | OMIM ID: 603397 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF282:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF282 | 8427 | 212892_at | 0.2495 | 0.5786 | |
| GSE20347 | ZNF282 | 8427 | 212892_at | 0.3870 | 0.0006 | |
| GSE23400 | ZNF282 | 8427 | 212892_at | 0.2013 | 0.0002 | |
| GSE26886 | ZNF282 | 8427 | 212892_at | 0.0006 | 0.9978 | |
| GSE29001 | ZNF282 | 8427 | 212892_at | 0.2504 | 0.2216 | |
| GSE38129 | ZNF282 | 8427 | 212892_at | 0.3411 | 0.0002 | |
| GSE45670 | ZNF282 | 8427 | 212892_at | 0.4197 | 0.0018 | |
| GSE53622 | ZNF282 | 8427 | 29768 | 0.4061 | 0.0006 | |
| GSE53624 | ZNF282 | 8427 | 29768 | 0.4328 | 0.0001 | |
| GSE63941 | ZNF282 | 8427 | 212892_at | 0.4398 | 0.1759 | |
| GSE77861 | ZNF282 | 8427 | 212892_at | 0.4351 | 0.1056 | |
| SRP007169 | ZNF282 | 8427 | RNAseq | -0.1045 | 0.8321 | |
| SRP008496 | ZNF282 | 8427 | RNAseq | -0.1049 | 0.7404 | |
| SRP064894 | ZNF282 | 8427 | RNAseq | 0.4709 | 0.0025 | |
| SRP133303 | ZNF282 | 8427 | RNAseq | 0.2515 | 0.0671 | |
| SRP159526 | ZNF282 | 8427 | RNAseq | 0.3021 | 0.0456 | |
| SRP193095 | ZNF282 | 8427 | RNAseq | 0.2680 | 0.0133 | |
| SRP219564 | ZNF282 | 8427 | RNAseq | 0.1269 | 0.6384 | |
| TCGA | ZNF282 | 8427 | RNAseq | 0.1171 | 0.0238 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ZNF282 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF282:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF282 | 8427 | 2 | 3 | 25 | |
| GSE20123 | ZNF282 | 8427 | 2 | 3 | 25 | |
| GSE43470 | ZNF282 | 8427 | 2 | 5 | 36 | |
| GSE46452 | ZNF282 | 8427 | 7 | 2 | 50 | |
| GSE47630 | ZNF282 | 8427 | 6 | 8 | 26 | |
| GSE54993 | ZNF282 | 8427 | 3 | 3 | 64 | |
| GSE54994 | ZNF282 | 8427 | 5 | 8 | 40 | |
| GSE60625 | ZNF282 | 8427 | 0 | 0 | 11 | |
| GSE74703 | ZNF282 | 8427 | 2 | 4 | 30 | |
| GSE74704 | ZNF282 | 8427 | 1 | 3 | 16 | |
| TCGA | ZNF282 | 8427 | 26 | 27 | 43 |
Total number of gains: 56; Total number of losses: 66; Total Number of normals: 366.
Somatic mutations of ZNF282:
Generating mutation plots.
Highly correlated genes for ZNF282:
Showing top 20/359 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF282 | NACC1 | 0.692551 | 3 | 0 | 3 |
| ZNF282 | CLCN6 | 0.690169 | 3 | 0 | 3 |
| ZNF282 | LRRC41 | 0.690127 | 3 | 0 | 3 |
| ZNF282 | AGAP2-AS1 | 0.687732 | 3 | 0 | 3 |
| ZNF282 | FADS3 | 0.676259 | 3 | 0 | 3 |
| ZNF282 | SLC25A1 | 0.671172 | 4 | 0 | 4 |
| ZNF282 | NFKBIL1 | 0.665109 | 3 | 0 | 3 |
| ZNF282 | TAPBP | 0.651866 | 4 | 0 | 4 |
| ZNF282 | TEAD4 | 0.637863 | 6 | 0 | 5 |
| ZNF282 | SHKBP1 | 0.637323 | 3 | 0 | 3 |
| ZNF282 | MAZ | 0.625339 | 7 | 0 | 6 |
| ZNF282 | ABHD15 | 0.62143 | 3 | 0 | 3 |
| ZNF282 | AURKAIP1 | 0.61609 | 3 | 0 | 3 |
| ZNF282 | NXPE3 | 0.614652 | 4 | 0 | 4 |
| ZNF282 | ZNF319 | 0.611832 | 4 | 0 | 3 |
| ZNF282 | RAB8A | 0.610135 | 4 | 0 | 3 |
| ZNF282 | DBF4 | 0.609871 | 5 | 0 | 5 |
| ZNF282 | SPNS1 | 0.608449 | 3 | 0 | 3 |
| ZNF282 | POMGNT1 | 0.605857 | 4 | 0 | 3 |
| ZNF282 | ELOF1 | 0.603941 | 5 | 0 | 3 |
For details and further investigation, click here
