| Full name: nuclear factor related to kappaB binding protein | Alias Symbol: DKFZp547B2013|INO80G | ||
| Type: protein-coding gene | Cytoband: 11q24.3 | ||
| Entrez ID: 4798 | HGNC ID: HGNC:7802 | Ensembl Gene: ENSG00000170322 | OMIM ID: 164013 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NFRKB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFRKB | 4798 | 213028_at | 0.3272 | 0.1282 | |
| GSE20347 | NFRKB | 4798 | 213028_at | 0.1378 | 0.2037 | |
| GSE23400 | NFRKB | 4798 | 213028_at | 0.0032 | 0.9514 | |
| GSE26886 | NFRKB | 4798 | 213028_at | -0.1888 | 0.2841 | |
| GSE29001 | NFRKB | 4798 | 213028_at | -0.0191 | 0.9545 | |
| GSE38129 | NFRKB | 4798 | 213028_at | 0.0721 | 0.4613 | |
| GSE45670 | NFRKB | 4798 | 213028_at | 0.1118 | 0.2509 | |
| GSE53622 | NFRKB | 4798 | 23949 | 0.0066 | 0.9181 | |
| GSE53624 | NFRKB | 4798 | 23949 | -0.0797 | 0.2330 | |
| GSE63941 | NFRKB | 4798 | 213028_at | -0.0824 | 0.8903 | |
| GSE77861 | NFRKB | 4798 | 213028_at | 0.2128 | 0.1478 | |
| GSE97050 | NFRKB | 4798 | A_23_P24485 | 0.0613 | 0.7620 | |
| SRP007169 | NFRKB | 4798 | RNAseq | 0.5368 | 0.2764 | |
| SRP008496 | NFRKB | 4798 | RNAseq | 0.2681 | 0.4452 | |
| SRP064894 | NFRKB | 4798 | RNAseq | -0.0753 | 0.6039 | |
| SRP133303 | NFRKB | 4798 | RNAseq | -0.5058 | 0.0000 | |
| SRP159526 | NFRKB | 4798 | RNAseq | -0.6167 | 0.0338 | |
| SRP193095 | NFRKB | 4798 | RNAseq | -0.2788 | 0.0052 | |
| SRP219564 | NFRKB | 4798 | RNAseq | -0.2100 | 0.6222 | |
| TCGA | NFRKB | 4798 | RNAseq | -0.0462 | 0.3878 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NFRKB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFRKB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFRKB | 4798 | 0 | 13 | 17 | |
| GSE20123 | NFRKB | 4798 | 0 | 13 | 17 | |
| GSE43470 | NFRKB | 4798 | 2 | 7 | 34 | |
| GSE46452 | NFRKB | 4798 | 3 | 26 | 30 | |
| GSE47630 | NFRKB | 4798 | 2 | 19 | 19 | |
| GSE54993 | NFRKB | 4798 | 10 | 0 | 60 | |
| GSE54994 | NFRKB | 4798 | 5 | 19 | 29 | |
| GSE60625 | NFRKB | 4798 | 0 | 3 | 8 | |
| GSE74703 | NFRKB | 4798 | 1 | 5 | 30 | |
| GSE74704 | NFRKB | 4798 | 0 | 9 | 11 | |
| TCGA | NFRKB | 4798 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of NFRKB:
Generating mutation plots.
Highly correlated genes for NFRKB:
Showing top 20/78 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFRKB | LSR | 0.718731 | 3 | 0 | 3 |
| NFRKB | ZNF329 | 0.690471 | 3 | 0 | 3 |
| NFRKB | CASC15 | 0.671879 | 3 | 0 | 3 |
| NFRKB | SEC16A | 0.671291 | 3 | 0 | 3 |
| NFRKB | NSUN2 | 0.658342 | 3 | 0 | 3 |
| NFRKB | ADAMTSL2 | 0.65618 | 3 | 0 | 3 |
| NFRKB | RBM28 | 0.649854 | 3 | 0 | 3 |
| NFRKB | CD72 | 0.645116 | 3 | 0 | 3 |
| NFRKB | FBRSL1 | 0.644918 | 4 | 0 | 4 |
| NFRKB | VMA21 | 0.637085 | 3 | 0 | 3 |
| NFRKB | RAVER1 | 0.636508 | 5 | 0 | 4 |
| NFRKB | C8G | 0.627344 | 3 | 0 | 3 |
| NFRKB | EVL | 0.626934 | 3 | 0 | 3 |
| NFRKB | TIGD1 | 0.621017 | 3 | 0 | 3 |
| NFRKB | RASIP1 | 0.619011 | 3 | 0 | 3 |
| NFRKB | RIT2 | 0.615106 | 3 | 0 | 3 |
| NFRKB | IFFO1 | 0.61432 | 3 | 0 | 3 |
| NFRKB | IGSF9 | 0.613106 | 4 | 0 | 3 |
| NFRKB | LENG8 | 0.612794 | 3 | 0 | 3 |
| NFRKB | GEMIN4 | 0.605411 | 3 | 0 | 3 |
For details and further investigation, click here
