| Full name: SEC16 homolog A, endoplasmic reticulum export factor | Alias Symbol: p250|Sec16L | ||
| Type: protein-coding gene | Cytoband: 9q34.3 | ||
| Entrez ID: 9919 | HGNC ID: HGNC:29006 | Ensembl Gene: ENSG00000148396 | OMIM ID: 612854 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SEC16A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SEC16A | 9919 | 215696_s_at | 0.3344 | 0.4062 | |
| GSE20347 | SEC16A | 9919 | 215696_s_at | -0.0665 | 0.6571 | |
| GSE23400 | SEC16A | 9919 | 215696_s_at | 0.3408 | 0.0000 | |
| GSE26886 | SEC16A | 9919 | 215696_s_at | 0.5747 | 0.0086 | |
| GSE29001 | SEC16A | 9919 | 215696_s_at | 0.2456 | 0.1467 | |
| GSE38129 | SEC16A | 9919 | 215696_s_at | 0.0666 | 0.6351 | |
| GSE45670 | SEC16A | 9919 | 215696_s_at | 0.1469 | 0.3259 | |
| GSE53622 | SEC16A | 9919 | 85813 | -0.1655 | 0.0011 | |
| GSE53624 | SEC16A | 9919 | 85813 | 0.0294 | 0.6868 | |
| GSE63941 | SEC16A | 9919 | 215696_s_at | -0.3916 | 0.3578 | |
| GSE77861 | SEC16A | 9919 | 215696_s_at | 0.4396 | 0.0264 | |
| GSE97050 | SEC16A | 9919 | A_23_P251303 | -0.1846 | 0.3751 | |
| SRP007169 | SEC16A | 9919 | RNAseq | 0.4957 | 0.2031 | |
| SRP008496 | SEC16A | 9919 | RNAseq | 0.3723 | 0.1042 | |
| SRP064894 | SEC16A | 9919 | RNAseq | 0.2791 | 0.0544 | |
| SRP133303 | SEC16A | 9919 | RNAseq | 0.1941 | 0.2452 | |
| SRP159526 | SEC16A | 9919 | RNAseq | 0.1806 | 0.4714 | |
| SRP193095 | SEC16A | 9919 | RNAseq | 0.1203 | 0.4189 | |
| SRP219564 | SEC16A | 9919 | RNAseq | 0.2111 | 0.2143 | |
| TCGA | SEC16A | 9919 | RNAseq | -0.1917 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SEC16A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SEC16A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SEC16A | 9919 | 4 | 7 | 19 | |
| GSE20123 | SEC16A | 9919 | 4 | 7 | 19 | |
| GSE43470 | SEC16A | 9919 | 3 | 7 | 33 | |
| GSE46452 | SEC16A | 9919 | 6 | 13 | 40 | |
| GSE47630 | SEC16A | 9919 | 6 | 15 | 19 | |
| GSE54993 | SEC16A | 9919 | 3 | 3 | 64 | |
| GSE54994 | SEC16A | 9919 | 13 | 7 | 33 | |
| GSE60625 | SEC16A | 9919 | 0 | 0 | 11 | |
| GSE74703 | SEC16A | 9919 | 3 | 5 | 28 | |
| GSE74704 | SEC16A | 9919 | 2 | 5 | 13 | |
| TCGA | SEC16A | 9919 | 29 | 24 | 43 |
Total number of gains: 73; Total number of losses: 93; Total Number of normals: 322.
Somatic mutations of SEC16A:
Generating mutation plots.
Highly correlated genes for SEC16A:
Showing top 20/529 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SEC16A | GNA13 | 0.826082 | 3 | 0 | 3 |
| SEC16A | SLC38A7 | 0.803991 | 3 | 0 | 3 |
| SEC16A | SOCS4 | 0.780528 | 3 | 0 | 3 |
| SEC16A | TMTC4 | 0.768289 | 3 | 0 | 3 |
| SEC16A | BOD1 | 0.767466 | 3 | 0 | 3 |
| SEC16A | KBTBD6 | 0.76697 | 3 | 0 | 3 |
| SEC16A | RNF217 | 0.757774 | 4 | 0 | 4 |
| SEC16A | PRDM15 | 0.755212 | 4 | 0 | 4 |
| SEC16A | ZNF284 | 0.754126 | 4 | 0 | 3 |
| SEC16A | NACC1 | 0.753222 | 4 | 0 | 4 |
| SEC16A | KANSL3 | 0.750655 | 3 | 0 | 3 |
| SEC16A | CSNK2A2 | 0.749367 | 3 | 0 | 3 |
| SEC16A | TANC2 | 0.747736 | 3 | 0 | 3 |
| SEC16A | TADA1 | 0.745222 | 3 | 0 | 3 |
| SEC16A | ZC3H18 | 0.744263 | 3 | 0 | 3 |
| SEC16A | RFNG | 0.743367 | 4 | 0 | 4 |
| SEC16A | XRCC1 | 0.740322 | 3 | 0 | 3 |
| SEC16A | ZNF655 | 0.740228 | 3 | 0 | 3 |
| SEC16A | RBM15B | 0.738645 | 3 | 0 | 3 |
| SEC16A | ZNF202 | 0.737346 | 3 | 0 | 3 |
For details and further investigation, click here
