| Full name: nescient helix-loop-helix 1 | Alias Symbol: NSCL|NSCL1|bHLHa35 | ||
| Type: protein-coding gene | Cytoband: 1q23.2 | ||
| Entrez ID: 4807 | HGNC ID: HGNC:7817 | Ensembl Gene: ENSG00000171786 | OMIM ID: 162360 |
| Drug and gene relationship at DGIdb | |||
Expression of NHLH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NHLH1 | 4807 | 214628_at | 0.0870 | 0.7847 | |
| GSE20347 | NHLH1 | 4807 | 214628_at | 0.1814 | 0.0889 | |
| GSE23400 | NHLH1 | 4807 | 214628_at | 0.0090 | 0.8161 | |
| GSE26886 | NHLH1 | 4807 | 214628_at | 0.0792 | 0.4937 | |
| GSE29001 | NHLH1 | 4807 | 214628_at | -0.0905 | 0.6896 | |
| GSE38129 | NHLH1 | 4807 | 214628_at | 0.0308 | 0.8062 | |
| GSE45670 | NHLH1 | 4807 | 214628_at | 0.2423 | 0.1508 | |
| GSE53622 | NHLH1 | 4807 | 49878 | -0.1779 | 0.0970 | |
| GSE53624 | NHLH1 | 4807 | 49878 | -0.0511 | 0.6015 | |
| GSE63941 | NHLH1 | 4807 | 214628_at | 0.2200 | 0.1895 | |
| GSE77861 | NHLH1 | 4807 | 214628_at | 0.0396 | 0.7614 | |
| GSE97050 | NHLH1 | 4807 | A_24_P336474 | 0.0740 | 0.7778 | |
| TCGA | NHLH1 | 4807 | RNAseq | 0.6955 | 0.0116 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NHLH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NHLH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NHLH1 | 4807 | 10 | 0 | 20 | |
| GSE20123 | NHLH1 | 4807 | 10 | 0 | 20 | |
| GSE43470 | NHLH1 | 4807 | 7 | 2 | 34 | |
| GSE46452 | NHLH1 | 4807 | 2 | 1 | 56 | |
| GSE47630 | NHLH1 | 4807 | 14 | 0 | 26 | |
| GSE54993 | NHLH1 | 4807 | 0 | 5 | 65 | |
| GSE54994 | NHLH1 | 4807 | 16 | 0 | 37 | |
| GSE60625 | NHLH1 | 4807 | 0 | 0 | 11 | |
| GSE74703 | NHLH1 | 4807 | 7 | 2 | 27 | |
| GSE74704 | NHLH1 | 4807 | 4 | 0 | 16 | |
| TCGA | NHLH1 | 4807 | 44 | 3 | 49 |
Total number of gains: 114; Total number of losses: 13; Total Number of normals: 361.
Somatic mutations of NHLH1:
Generating mutation plots.
Highly correlated genes for NHLH1:
Showing top 20/680 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NHLH1 | PRLR | 0.766656 | 4 | 0 | 4 |
| NHLH1 | USP34 | 0.737429 | 3 | 0 | 3 |
| NHLH1 | TAOK2 | 0.735331 | 3 | 0 | 3 |
| NHLH1 | IGH | 0.720111 | 3 | 0 | 3 |
| NHLH1 | LINC01361 | 0.717674 | 3 | 0 | 3 |
| NHLH1 | RAMP2 | 0.716425 | 3 | 0 | 3 |
| NHLH1 | POU3F4 | 0.706621 | 5 | 0 | 5 |
| NHLH1 | MC2R | 0.706157 | 5 | 0 | 4 |
| NHLH1 | KRT84 | 0.703419 | 3 | 0 | 3 |
| NHLH1 | PAPPA2 | 0.700128 | 4 | 0 | 3 |
| NHLH1 | HAO2 | 0.693965 | 4 | 0 | 4 |
| NHLH1 | GAD2 | 0.690813 | 4 | 0 | 4 |
| NHLH1 | USP5 | 0.686076 | 4 | 0 | 4 |
| NHLH1 | GABRG2 | 0.685677 | 3 | 0 | 3 |
| NHLH1 | NXPE4 | 0.685648 | 4 | 0 | 3 |
| NHLH1 | MAPK8IP3 | 0.679596 | 5 | 0 | 5 |
| NHLH1 | SLC45A2 | 0.679218 | 3 | 0 | 3 |
| NHLH1 | TBR1 | 0.678237 | 5 | 0 | 5 |
| NHLH1 | RET | 0.674806 | 3 | 0 | 3 |
| NHLH1 | OR52A1 | 0.671522 | 4 | 0 | 3 |
For details and further investigation, click here
