| Full name: keratin 84 | Alias Symbol: Hb-4 | ||
| Type: protein-coding gene | Cytoband: 12q13.13 | ||
| Entrez ID: 3890 | HGNC ID: HGNC:6461 | Ensembl Gene: ENSG00000161849 | OMIM ID: 602766 |
| Drug and gene relationship at DGIdb | |||
Expression of KRT84:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KRT84 | 3890 | 217031_at | 0.1195 | 0.5694 | |
| GSE20347 | KRT84 | 3890 | 217031_at | 0.0149 | 0.8675 | |
| GSE23400 | KRT84 | 3890 | 217031_at | -0.0134 | 0.7453 | |
| GSE26886 | KRT84 | 3890 | 217031_at | 0.1625 | 0.1000 | |
| GSE29001 | KRT84 | 3890 | 217031_at | -0.0705 | 0.7036 | |
| GSE38129 | KRT84 | 3890 | 217031_at | -0.0534 | 0.3992 | |
| GSE45670 | KRT84 | 3890 | 217031_at | 0.1577 | 0.0948 | |
| GSE53622 | KRT84 | 3890 | 157086 | 0.8081 | 0.0005 | |
| GSE53624 | KRT84 | 3890 | 157086 | 0.4943 | 0.0002 | |
| GSE63941 | KRT84 | 3890 | 217031_at | 0.0446 | 0.8089 | |
| GSE77861 | KRT84 | 3890 | 217031_at | 0.0274 | 0.8518 | |
| TCGA | KRT84 | 3890 | RNAseq | 3.7367 | 0.0001 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by KRT84 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KRT84:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KRT84 | 3890 | 8 | 1 | 21 | |
| GSE20123 | KRT84 | 3890 | 8 | 1 | 21 | |
| GSE43470 | KRT84 | 3890 | 3 | 0 | 40 | |
| GSE46452 | KRT84 | 3890 | 7 | 1 | 51 | |
| GSE47630 | KRT84 | 3890 | 10 | 2 | 28 | |
| GSE54993 | KRT84 | 3890 | 0 | 5 | 65 | |
| GSE54994 | KRT84 | 3890 | 4 | 1 | 48 | |
| GSE60625 | KRT84 | 3890 | 0 | 0 | 11 | |
| GSE74703 | KRT84 | 3890 | 3 | 0 | 33 | |
| GSE74704 | KRT84 | 3890 | 5 | 1 | 14 | |
| TCGA | KRT84 | 3890 | 12 | 11 | 73 |
Total number of gains: 60; Total number of losses: 23; Total Number of normals: 405.
Somatic mutations of KRT84:
Generating mutation plots.
Highly correlated genes for KRT84:
Showing top 20/475 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KRT84 | ZMAT4 | 0.727071 | 3 | 0 | 3 |
| KRT84 | IFNA10 | 0.720868 | 3 | 0 | 3 |
| KRT84 | FAM66D | 0.708091 | 3 | 0 | 3 |
| KRT84 | NHLH1 | 0.703419 | 3 | 0 | 3 |
| KRT84 | RBFADN | 0.699158 | 4 | 0 | 4 |
| KRT84 | RNF17 | 0.692549 | 3 | 0 | 3 |
| KRT84 | FRAS1 | 0.679435 | 3 | 0 | 3 |
| KRT84 | FBXL18 | 0.674728 | 5 | 0 | 5 |
| KRT84 | COL25A1 | 0.672924 | 3 | 0 | 3 |
| KRT84 | LAT2 | 0.672254 | 3 | 0 | 3 |
| KRT84 | CPA2 | 0.666793 | 3 | 0 | 3 |
| KRT84 | IFNA7 | 0.664897 | 4 | 0 | 4 |
| KRT84 | GDF5 | 0.661403 | 4 | 0 | 3 |
| KRT84 | IL1RAPL2 | 0.659672 | 4 | 0 | 3 |
| KRT84 | TCTN2 | 0.656291 | 4 | 0 | 3 |
| KRT84 | IFNA14 | 0.652909 | 4 | 0 | 4 |
| KRT84 | PLCB2 | 0.651554 | 4 | 0 | 4 |
| KRT84 | CRHR2 | 0.648297 | 5 | 0 | 4 |
| KRT84 | RCVRN | 0.647008 | 5 | 0 | 3 |
| KRT84 | KCNC4 | 0.643195 | 5 | 0 | 5 |
For details and further investigation, click here
