| Full name: pericentrin | Alias Symbol: KEN|KIAA0402|PCN|PCNTB|SCKL4 | ||
| Type: protein-coding gene | Cytoband: 21q22.3 | ||
| Entrez ID: 5116 | HGNC ID: HGNC:16068 | Ensembl Gene: ENSG00000160299 | OMIM ID: 605925 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of PCNT:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCNT | 5116 | 203660_s_at | 0.1554 | 0.8132 | |
| GSE20347 | PCNT | 5116 | 203660_s_at | -0.0574 | 0.7177 | |
| GSE23400 | PCNT | 5116 | 203660_s_at | -0.0217 | 0.6651 | |
| GSE26886 | PCNT | 5116 | 203660_s_at | -0.6729 | 0.0048 | |
| GSE29001 | PCNT | 5116 | 203660_s_at | 0.0010 | 0.9970 | |
| GSE38129 | PCNT | 5116 | 203660_s_at | -0.1051 | 0.3502 | |
| GSE45670 | PCNT | 5116 | 203660_s_at | 0.1482 | 0.3942 | |
| GSE53622 | PCNT | 5116 | 97610 | -0.3389 | 0.0000 | |
| GSE53624 | PCNT | 5116 | 67039 | -0.2025 | 0.0003 | |
| GSE63941 | PCNT | 5116 | 203660_s_at | -0.1069 | 0.8000 | |
| GSE77861 | PCNT | 5116 | 203660_s_at | -0.4168 | 0.0774 | |
| GSE97050 | PCNT | 5116 | A_23_P57347 | -0.1464 | 0.4951 | |
| SRP007169 | PCNT | 5116 | RNAseq | 0.2353 | 0.6524 | |
| SRP008496 | PCNT | 5116 | RNAseq | 0.2785 | 0.4383 | |
| SRP064894 | PCNT | 5116 | RNAseq | 0.3069 | 0.1853 | |
| SRP133303 | PCNT | 5116 | RNAseq | -0.3582 | 0.0266 | |
| SRP159526 | PCNT | 5116 | RNAseq | -0.1001 | 0.6118 | |
| SRP193095 | PCNT | 5116 | RNAseq | 0.2029 | 0.1588 | |
| SRP219564 | PCNT | 5116 | RNAseq | -0.0568 | 0.8219 | |
| TCGA | PCNT | 5116 | RNAseq | -0.0116 | 0.8211 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCNT expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCNT:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCNT | 5116 | 3 | 9 | 18 | |
| GSE20123 | PCNT | 5116 | 3 | 9 | 18 | |
| GSE43470 | PCNT | 5116 | 0 | 14 | 29 | |
| GSE46452 | PCNT | 5116 | 1 | 21 | 37 | |
| GSE47630 | PCNT | 5116 | 6 | 17 | 17 | |
| GSE54993 | PCNT | 5116 | 8 | 1 | 61 | |
| GSE54994 | PCNT | 5116 | 5 | 8 | 40 | |
| GSE60625 | PCNT | 5116 | 0 | 0 | 11 | |
| GSE74703 | PCNT | 5116 | 0 | 10 | 26 | |
| GSE74704 | PCNT | 5116 | 1 | 5 | 14 | |
| TCGA | PCNT | 5116 | 10 | 37 | 49 |
Total number of gains: 37; Total number of losses: 131; Total Number of normals: 320.
Somatic mutations of PCNT:
Generating mutation plots.
Highly correlated genes for PCNT:
Showing top 20/370 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCNT | NIPAL3 | 0.807676 | 3 | 0 | 3 |
| PCNT | POGK | 0.804224 | 3 | 0 | 3 |
| PCNT | GDAP2 | 0.777302 | 3 | 0 | 3 |
| PCNT | VPS45 | 0.777204 | 3 | 0 | 3 |
| PCNT | AGPAT3 | 0.776229 | 5 | 0 | 4 |
| PCNT | NR2C2 | 0.774429 | 3 | 0 | 3 |
| PCNT | LEMD2 | 0.768921 | 3 | 0 | 3 |
| PCNT | YIPF3 | 0.768321 | 3 | 0 | 3 |
| PCNT | PPP1R3D | 0.76272 | 3 | 0 | 3 |
| PCNT | LINC01138 | 0.761415 | 3 | 0 | 3 |
| PCNT | SLC35B3 | 0.757466 | 3 | 0 | 3 |
| PCNT | PEPD | 0.745968 | 3 | 0 | 3 |
| PCNT | ARF5 | 0.740372 | 3 | 0 | 3 |
| PCNT | IFNGR2 | 0.739636 | 3 | 0 | 3 |
| PCNT | PUS10 | 0.738343 | 3 | 0 | 3 |
| PCNT | FAM53B | 0.736721 | 4 | 0 | 3 |
| PCNT | SEMA4A | 0.730918 | 3 | 0 | 3 |
| PCNT | ARSD | 0.728658 | 3 | 0 | 3 |
| PCNT | NDUFS3 | 0.726473 | 4 | 0 | 3 |
| PCNT | ATG4A | 0.724827 | 3 | 0 | 3 |
For details and further investigation, click here
