| Full name: peroxisomal biogenesis factor 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 6q24.2 | ||
| Entrez ID: 8504 | HGNC ID: HGNC:8858 | Ensembl Gene: ENSG00000034693 | OMIM ID: 603164 |
| Drug and gene relationship at DGIdb | |||
Expression of PEX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PEX3 | 8504 | 203972_s_at | -0.4758 | 0.3368 | |
| GSE20347 | PEX3 | 8504 | 203972_s_at | -0.5628 | 0.0206 | |
| GSE23400 | PEX3 | 8504 | 203972_s_at | -0.1008 | 0.1983 | |
| GSE26886 | PEX3 | 8504 | 203972_s_at | -0.5542 | 0.0100 | |
| GSE29001 | PEX3 | 8504 | 203972_s_at | -0.4270 | 0.3592 | |
| GSE38129 | PEX3 | 8504 | 203972_s_at | -0.1850 | 0.3609 | |
| GSE45670 | PEX3 | 8504 | 203972_s_at | -0.4069 | 0.0056 | |
| GSE53622 | PEX3 | 8504 | 19115 | -0.5330 | 0.0000 | |
| GSE53624 | PEX3 | 8504 | 19115 | -0.6209 | 0.0000 | |
| GSE63941 | PEX3 | 8504 | 203972_s_at | 0.4053 | 0.4161 | |
| GSE77861 | PEX3 | 8504 | 203972_s_at | -0.8406 | 0.0509 | |
| GSE97050 | PEX3 | 8504 | A_33_P3243588 | 0.0366 | 0.9034 | |
| SRP007169 | PEX3 | 8504 | RNAseq | -1.0462 | 0.0042 | |
| SRP008496 | PEX3 | 8504 | RNAseq | -0.6662 | 0.0077 | |
| SRP064894 | PEX3 | 8504 | RNAseq | -0.7430 | 0.0001 | |
| SRP133303 | PEX3 | 8504 | RNAseq | -0.4958 | 0.0006 | |
| SRP159526 | PEX3 | 8504 | RNAseq | -0.9237 | 0.0002 | |
| SRP193095 | PEX3 | 8504 | RNAseq | -0.6692 | 0.0000 | |
| SRP219564 | PEX3 | 8504 | RNAseq | -1.2004 | 0.0021 | |
| TCGA | PEX3 | 8504 | RNAseq | -0.0881 | 0.1274 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by PEX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PEX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PEX3 | 8504 | 2 | 4 | 24 | |
| GSE20123 | PEX3 | 8504 | 2 | 3 | 25 | |
| GSE43470 | PEX3 | 8504 | 5 | 0 | 38 | |
| GSE46452 | PEX3 | 8504 | 3 | 10 | 46 | |
| GSE47630 | PEX3 | 8504 | 9 | 4 | 27 | |
| GSE54993 | PEX3 | 8504 | 3 | 2 | 65 | |
| GSE54994 | PEX3 | 8504 | 8 | 8 | 37 | |
| GSE60625 | PEX3 | 8504 | 0 | 1 | 10 | |
| GSE74703 | PEX3 | 8504 | 4 | 0 | 32 | |
| GSE74704 | PEX3 | 8504 | 0 | 1 | 19 | |
| TCGA | PEX3 | 8504 | 11 | 19 | 66 |
Total number of gains: 47; Total number of losses: 52; Total Number of normals: 389.
Somatic mutations of PEX3:
Generating mutation plots.
Highly correlated genes for PEX3:
Showing top 20/1232 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PEX3 | STAMBP | 0.746424 | 4 | 0 | 4 |
| PEX3 | NIPAL3 | 0.745465 | 3 | 0 | 3 |
| PEX3 | RALGPS2 | 0.738172 | 6 | 0 | 6 |
| PEX3 | OCIAD1 | 0.738148 | 3 | 0 | 3 |
| PEX3 | SEC11C | 0.73808 | 3 | 0 | 3 |
| PEX3 | CDKL1 | 0.731114 | 3 | 0 | 3 |
| PEX3 | CBLL1 | 0.727696 | 3 | 0 | 3 |
| PEX3 | SUGT1 | 0.720026 | 3 | 0 | 3 |
| PEX3 | CRBN | 0.719546 | 4 | 0 | 4 |
| PEX3 | TTC17 | 0.717902 | 3 | 0 | 3 |
| PEX3 | PLEKHF2 | 0.714746 | 5 | 0 | 4 |
| PEX3 | LIPT1 | 0.701773 | 4 | 0 | 3 |
| PEX3 | SLC30A5 | 0.699203 | 4 | 0 | 3 |
| PEX3 | ZDHHC21 | 0.698899 | 5 | 0 | 5 |
| PEX3 | SCP2 | 0.694579 | 8 | 0 | 7 |
| PEX3 | DNAJB14 | 0.694438 | 4 | 0 | 3 |
| PEX3 | CPVL | 0.693109 | 6 | 0 | 5 |
| PEX3 | SH3PXD2A-AS1 | 0.6919 | 4 | 0 | 3 |
| PEX3 | MAGT1 | 0.691404 | 5 | 0 | 5 |
| PEX3 | POLDIP2 | 0.690097 | 3 | 0 | 3 |
For details and further investigation, click here
