| Full name: nucleolar protein 12 | Alias Symbol: MGC3731|Nop25|RRP17 | ||
| Type: protein-coding gene | Cytoband: 22q13.1 | ||
| Entrez ID: 79159 | HGNC ID: HGNC:28585 | Ensembl Gene: ENSG00000273899 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NOL12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOL12 | 79159 | 219324_at | -0.1944 | 0.5119 | |
| GSE20347 | NOL12 | 79159 | 219324_at | -0.2248 | 0.1792 | |
| GSE23400 | NOL12 | 79159 | 219324_at | -0.1584 | 0.0128 | |
| GSE26886 | NOL12 | 79159 | 219324_at | 0.2157 | 0.2248 | |
| GSE29001 | NOL12 | 79159 | 222057_at | -0.2298 | 0.2493 | |
| GSE38129 | NOL12 | 79159 | 219324_at | 0.0386 | 0.8265 | |
| GSE45670 | NOL12 | 79159 | 219324_at | -0.1273 | 0.5418 | |
| GSE53622 | NOL12 | 79159 | 168173 | -0.1853 | 0.0885 | |
| GSE53624 | NOL12 | 79159 | 46872 | -0.0150 | 0.8722 | |
| GSE63941 | NOL12 | 79159 | 219324_at | 0.8148 | 0.0440 | |
| GSE77861 | NOL12 | 79159 | 219324_at | -0.0137 | 0.9532 | |
| GSE97050 | NOL12 | 79159 | A_33_P3417820 | 0.0953 | 0.7709 | |
| SRP007169 | NOL12 | 79159 | RNAseq | -0.6598 | 0.1319 | |
| SRP064894 | NOL12 | 79159 | RNAseq | -0.0551 | 0.7933 | |
| SRP133303 | NOL12 | 79159 | RNAseq | -0.3341 | 0.0417 | |
| SRP159526 | NOL12 | 79159 | RNAseq | -0.1953 | 0.3337 | |
| SRP193095 | NOL12 | 79159 | RNAseq | -0.2180 | 0.0835 | |
| SRP219564 | NOL12 | 79159 | RNAseq | -0.0415 | 0.9161 | |
| TCGA | NOL12 | 79159 | RNAseq | 0.1464 | 0.0245 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NOL12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOL12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOL12 | 79159 | 6 | 5 | 19 | |
| GSE20123 | NOL12 | 79159 | 6 | 4 | 20 | |
| GSE43470 | NOL12 | 79159 | 4 | 6 | 33 | |
| GSE46452 | NOL12 | 79159 | 32 | 2 | 25 | |
| GSE47630 | NOL12 | 79159 | 9 | 4 | 27 | |
| GSE54993 | NOL12 | 79159 | 3 | 6 | 61 | |
| GSE54994 | NOL12 | 79159 | 9 | 8 | 36 | |
| GSE60625 | NOL12 | 79159 | 5 | 0 | 6 | |
| GSE74703 | NOL12 | 79159 | 4 | 4 | 28 | |
| GSE74704 | NOL12 | 79159 | 3 | 2 | 15 | |
| TCGA | NOL12 | 79159 | 27 | 15 | 54 |
Total number of gains: 108; Total number of losses: 56; Total Number of normals: 324.
Somatic mutations of NOL12:
Generating mutation plots.
Highly correlated genes for NOL12:
Showing top 20/315 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOL12 | CLDN18 | 0.755114 | 3 | 0 | 3 |
| NOL12 | ZNF408 | 0.751112 | 3 | 0 | 3 |
| NOL12 | C11orf68 | 0.745343 | 3 | 0 | 3 |
| NOL12 | C19orf54 | 0.727066 | 3 | 0 | 3 |
| NOL12 | C2CD2L | 0.725329 | 4 | 0 | 4 |
| NOL12 | SNX15 | 0.721381 | 3 | 0 | 3 |
| NOL12 | DUSP18 | 0.715336 | 3 | 0 | 3 |
| NOL12 | CCDC120 | 0.713302 | 3 | 0 | 3 |
| NOL12 | MED25 | 0.708712 | 5 | 0 | 4 |
| NOL12 | LDOC1 | 0.704541 | 3 | 0 | 3 |
| NOL12 | ULK3 | 0.703405 | 3 | 0 | 3 |
| NOL12 | CYP2C19 | 0.700757 | 3 | 0 | 3 |
| NOL12 | CCDC12 | 0.699075 | 3 | 0 | 3 |
| NOL12 | GAK | 0.698232 | 4 | 0 | 4 |
| NOL12 | PSMD5 | 0.692561 | 3 | 0 | 3 |
| NOL12 | SORD | 0.683893 | 3 | 0 | 3 |
| NOL12 | CD2BP2 | 0.683133 | 3 | 0 | 3 |
| NOL12 | SNRPA1 | 0.680787 | 3 | 0 | 3 |
| NOL12 | USP19 | 0.679613 | 3 | 0 | 3 |
| NOL12 | PLEKHA7 | 0.676779 | 4 | 0 | 4 |
For details and further investigation, click here
