| Full name: small nuclear ribonucleoprotein polypeptide A' | Alias Symbol: Lea1|U2A' | ||
| Type: protein-coding gene | Cytoband: 15q26.3 | ||
| Entrez ID: 6627 | HGNC ID: HGNC:11152 | Ensembl Gene: ENSG00000131876 | OMIM ID: 603521 |
| Drug and gene relationship at DGIdb | |||
Expression of SNRPA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRPA1 | 6627 | 206055_s_at | 0.4284 | 0.3510 | |
| GSE20347 | SNRPA1 | 6627 | 206055_s_at | 0.5004 | 0.0008 | |
| GSE23400 | SNRPA1 | 6627 | 206055_s_at | 0.5264 | 0.0000 | |
| GSE26886 | SNRPA1 | 6627 | 206055_s_at | 0.7294 | 0.0000 | |
| GSE29001 | SNRPA1 | 6627 | 206055_s_at | 0.5095 | 0.0100 | |
| GSE38129 | SNRPA1 | 6627 | 206055_s_at | 0.7864 | 0.0000 | |
| GSE45670 | SNRPA1 | 6627 | 206055_s_at | 0.2958 | 0.0417 | |
| GSE53622 | SNRPA1 | 6627 | 45238 | 0.5800 | 0.0000 | |
| GSE53624 | SNRPA1 | 6627 | 45238 | 0.6632 | 0.0000 | |
| GSE63941 | SNRPA1 | 6627 | 206055_s_at | 0.6069 | 0.2534 | |
| GSE77861 | SNRPA1 | 6627 | 206055_s_at | 0.4430 | 0.1528 | |
| GSE97050 | SNRPA1 | 6627 | A_32_P28685 | 0.1679 | 0.7072 | |
| SRP007169 | SNRPA1 | 6627 | RNAseq | 0.5757 | 0.1365 | |
| SRP008496 | SNRPA1 | 6627 | RNAseq | 0.8094 | 0.0277 | |
| SRP064894 | SNRPA1 | 6627 | RNAseq | 0.2938 | 0.0269 | |
| SRP133303 | SNRPA1 | 6627 | RNAseq | 0.5211 | 0.0041 | |
| SRP159526 | SNRPA1 | 6627 | RNAseq | 0.6404 | 0.0092 | |
| SRP193095 | SNRPA1 | 6627 | RNAseq | 0.1788 | 0.2162 | |
| SRP219564 | SNRPA1 | 6627 | RNAseq | 0.7343 | 0.1160 | |
| TCGA | SNRPA1 | 6627 | RNAseq | 0.3323 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SNRPA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRPA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRPA1 | 6627 | 6 | 2 | 22 | |
| GSE20123 | SNRPA1 | 6627 | 6 | 2 | 22 | |
| GSE43470 | SNRPA1 | 6627 | 6 | 5 | 32 | |
| GSE46452 | SNRPA1 | 6627 | 3 | 7 | 49 | |
| GSE47630 | SNRPA1 | 6627 | 9 | 10 | 21 | |
| GSE54993 | SNRPA1 | 6627 | 4 | 7 | 59 | |
| GSE54994 | SNRPA1 | 6627 | 8 | 7 | 38 | |
| GSE60625 | SNRPA1 | 6627 | 4 | 0 | 7 | |
| GSE74703 | SNRPA1 | 6627 | 5 | 4 | 27 | |
| GSE74704 | SNRPA1 | 6627 | 3 | 3 | 14 | |
| TCGA | SNRPA1 | 6627 | 19 | 10 | 67 |
Total number of gains: 73; Total number of losses: 57; Total Number of normals: 358.
Somatic mutations of SNRPA1:
Generating mutation plots.
Highly correlated genes for SNRPA1:
Showing top 20/1560 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRPA1 | NBEAL1 | 0.787668 | 3 | 0 | 3 |
| SNRPA1 | ANKS6 | 0.763994 | 3 | 0 | 3 |
| SNRPA1 | TNFRSF21 | 0.758944 | 3 | 0 | 3 |
| SNRPA1 | AP4E1 | 0.740942 | 3 | 0 | 3 |
| SNRPA1 | PRC1 | 0.737171 | 13 | 0 | 12 |
| SNRPA1 | INTS10 | 0.730771 | 4 | 0 | 3 |
| SNRPA1 | TBC1D2 | 0.730468 | 3 | 0 | 3 |
| SNRPA1 | SNRPG | 0.728735 | 12 | 0 | 11 |
| SNRPA1 | KNSTRN | 0.728152 | 7 | 0 | 7 |
| SNRPA1 | CMC1 | 0.727968 | 3 | 0 | 3 |
| SNRPA1 | MMS22L | 0.72613 | 3 | 0 | 3 |
| SNRPA1 | AFAP1L2 | 0.720625 | 3 | 0 | 3 |
| SNRPA1 | ANKRD50 | 0.720431 | 3 | 0 | 3 |
| SNRPA1 | RILPL2 | 0.716501 | 3 | 0 | 3 |
| SNRPA1 | MTHFD1L | 0.716056 | 3 | 0 | 3 |
| SNRPA1 | PPP6R3 | 0.714921 | 4 | 0 | 4 |
| SNRPA1 | TTBK2 | 0.714468 | 3 | 0 | 3 |
| SNRPA1 | UCK2 | 0.713685 | 4 | 0 | 4 |
| SNRPA1 | MASTL | 0.709104 | 7 | 0 | 7 |
| SNRPA1 | TAS2R19 | 0.706825 | 3 | 0 | 3 |
For details and further investigation, click here
