| Full name: sorbitol dehydrogenase | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 15q21.1 | ||
| Entrez ID: 6652 | HGNC ID: HGNC:11184 | Ensembl Gene: ENSG00000140263 | OMIM ID: 182500 |
| Drug and gene relationship at DGIdb | |||
Expression of SORD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SORD | 6652 | 201563_at | 0.4142 | 0.5211 | |
| GSE20347 | SORD | 6652 | 201563_at | 0.1668 | 0.3733 | |
| GSE23400 | SORD | 6652 | 201563_at | 0.3961 | 0.0107 | |
| GSE26886 | SORD | 6652 | 201563_at | -0.0585 | 0.8074 | |
| GSE29001 | SORD | 6652 | 201563_at | -0.1930 | 0.5470 | |
| GSE38129 | SORD | 6652 | 201563_at | 0.4917 | 0.0505 | |
| GSE45670 | SORD | 6652 | 201563_at | 0.6862 | 0.0013 | |
| GSE53622 | SORD | 6652 | 77330 | -0.0021 | 0.9885 | |
| GSE53624 | SORD | 6652 | 302 | -0.1753 | 0.1725 | |
| GSE63941 | SORD | 6652 | 201563_at | 1.8246 | 0.0014 | |
| GSE77861 | SORD | 6652 | 201563_at | 0.0408 | 0.9382 | |
| GSE97050 | SORD | 6652 | A_23_P77103 | 0.5085 | 0.2827 | |
| SRP007169 | SORD | 6652 | RNAseq | -0.9749 | 0.0481 | |
| SRP008496 | SORD | 6652 | RNAseq | -0.7018 | 0.0454 | |
| SRP064894 | SORD | 6652 | RNAseq | 0.1742 | 0.4874 | |
| SRP133303 | SORD | 6652 | RNAseq | 0.2119 | 0.5128 | |
| SRP159526 | SORD | 6652 | RNAseq | -0.1856 | 0.6373 | |
| SRP193095 | SORD | 6652 | RNAseq | -0.2817 | 0.0512 | |
| SRP219564 | SORD | 6652 | RNAseq | -0.2833 | 0.5931 | |
| TCGA | SORD | 6652 | RNAseq | 0.0391 | 0.6162 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by SORD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SORD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SORD | 6652 | 3 | 5 | 22 | |
| GSE20123 | SORD | 6652 | 3 | 5 | 22 | |
| GSE43470 | SORD | 6652 | 4 | 4 | 35 | |
| GSE46452 | SORD | 6652 | 3 | 7 | 49 | |
| GSE47630 | SORD | 6652 | 8 | 10 | 22 | |
| GSE54993 | SORD | 6652 | 5 | 5 | 60 | |
| GSE54994 | SORD | 6652 | 5 | 7 | 41 | |
| GSE60625 | SORD | 6652 | 4 | 0 | 7 | |
| GSE74703 | SORD | 6652 | 4 | 3 | 29 | |
| GSE74704 | SORD | 6652 | 1 | 3 | 16 | |
| TCGA | SORD | 6652 | 11 | 16 | 69 |
Total number of gains: 51; Total number of losses: 65; Total Number of normals: 372.
Somatic mutations of SORD:
Generating mutation plots.
Highly correlated genes for SORD:
Showing top 20/655 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SORD | MCCC2 | 0.843433 | 3 | 0 | 3 |
| SORD | ACTR2 | 0.806169 | 3 | 0 | 3 |
| SORD | MREG | 0.781442 | 4 | 0 | 4 |
| SORD | SLC50A1 | 0.777675 | 4 | 0 | 4 |
| SORD | MRPL30 | 0.769018 | 3 | 0 | 3 |
| SORD | EAF2 | 0.764443 | 3 | 0 | 3 |
| SORD | CHMP4C | 0.757165 | 3 | 0 | 3 |
| SORD | RAB25 | 0.749642 | 3 | 0 | 3 |
| SORD | ADAT1 | 0.748994 | 3 | 0 | 3 |
| SORD | FAM83B | 0.747914 | 3 | 0 | 3 |
| SORD | GMCL1 | 0.744484 | 3 | 0 | 3 |
| SORD | AP1M2 | 0.743374 | 4 | 0 | 4 |
| SORD | CYBA | 0.740614 | 3 | 0 | 3 |
| SORD | SH2D4A | 0.73956 | 3 | 0 | 3 |
| SORD | RCC1 | 0.73192 | 4 | 0 | 4 |
| SORD | FANCD2 | 0.730559 | 4 | 0 | 4 |
| SORD | ARNTL2 | 0.730537 | 3 | 0 | 3 |
| SORD | MCTP1 | 0.728797 | 3 | 0 | 3 |
| SORD | IAH1 | 0.728226 | 3 | 0 | 3 |
| SORD | C16orf70 | 0.727294 | 3 | 0 | 3 |
For details and further investigation, click here
