| Full name: NOVA alternative splicing regulator 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 14q12 | ||
| Entrez ID: 4857 | HGNC ID: HGNC:7886 | Ensembl Gene: ENSG00000139910 | OMIM ID: 602157 |
| Drug and gene relationship at DGIdb | |||
Expression of NOVA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NOVA1 | 4857 | 205794_s_at | -1.4606 | 0.1184 | |
| GSE20347 | NOVA1 | 4857 | 205794_s_at | -0.3676 | 0.0071 | |
| GSE23400 | NOVA1 | 4857 | 205794_s_at | -0.2393 | 0.0019 | |
| GSE26886 | NOVA1 | 4857 | 205794_s_at | -0.4659 | 0.0416 | |
| GSE29001 | NOVA1 | 4857 | 205794_s_at | -0.4000 | 0.1454 | |
| GSE38129 | NOVA1 | 4857 | 205794_s_at | -0.8505 | 0.0015 | |
| GSE45670 | NOVA1 | 4857 | 205794_s_at | -1.6577 | 0.0000 | |
| GSE53622 | NOVA1 | 4857 | 90723 | -0.7341 | 0.0000 | |
| GSE53624 | NOVA1 | 4857 | 90723 | -0.3552 | 0.0000 | |
| GSE63941 | NOVA1 | 4857 | 205794_s_at | -3.4540 | 0.0002 | |
| GSE77861 | NOVA1 | 4857 | 205794_s_at | 0.1021 | 0.4961 | |
| GSE97050 | NOVA1 | 4857 | A_33_P3347697 | -0.7896 | 0.1820 | |
| SRP064894 | NOVA1 | 4857 | RNAseq | 0.5734 | 0.2363 | |
| SRP133303 | NOVA1 | 4857 | RNAseq | -0.2627 | 0.3179 | |
| SRP159526 | NOVA1 | 4857 | RNAseq | 1.0445 | 0.2047 | |
| SRP193095 | NOVA1 | 4857 | RNAseq | -0.2732 | 0.3194 | |
| SRP219564 | NOVA1 | 4857 | RNAseq | -0.2098 | 0.8205 | |
| TCGA | NOVA1 | 4857 | RNAseq | -0.9403 | 0.0057 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by NOVA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NOVA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NOVA1 | 4857 | 8 | 4 | 18 | |
| GSE20123 | NOVA1 | 4857 | 8 | 4 | 18 | |
| GSE43470 | NOVA1 | 4857 | 9 | 2 | 32 | |
| GSE46452 | NOVA1 | 4857 | 16 | 2 | 41 | |
| GSE47630 | NOVA1 | 4857 | 11 | 10 | 19 | |
| GSE54993 | NOVA1 | 4857 | 3 | 11 | 56 | |
| GSE54994 | NOVA1 | 4857 | 18 | 5 | 30 | |
| GSE60625 | NOVA1 | 4857 | 0 | 2 | 9 | |
| GSE74703 | NOVA1 | 4857 | 8 | 2 | 26 | |
| GSE74704 | NOVA1 | 4857 | 3 | 3 | 14 | |
| TCGA | NOVA1 | 4857 | 28 | 15 | 53 |
Total number of gains: 112; Total number of losses: 60; Total Number of normals: 316.
Somatic mutations of NOVA1:
Generating mutation plots.
Highly correlated genes for NOVA1:
Showing top 20/953 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NOVA1 | FENDRR | 0.803116 | 4 | 0 | 4 |
| NOVA1 | MAGI2-AS3 | 0.801493 | 4 | 0 | 4 |
| NOVA1 | FXYD1 | 0.795515 | 7 | 0 | 7 |
| NOVA1 | RNF150 | 0.78833 | 5 | 0 | 5 |
| NOVA1 | NEXN | 0.78239 | 5 | 0 | 5 |
| NOVA1 | LRRN4CL | 0.76828 | 5 | 0 | 5 |
| NOVA1 | GALNT15 | 0.766844 | 3 | 0 | 3 |
| NOVA1 | INMT | 0.761763 | 6 | 0 | 6 |
| NOVA1 | LMO3 | 0.760693 | 7 | 0 | 6 |
| NOVA1 | TIMP4 | 0.756524 | 6 | 0 | 6 |
| NOVA1 | SHISA3 | 0.748363 | 4 | 0 | 4 |
| NOVA1 | C3orf70 | 0.747542 | 4 | 0 | 4 |
| NOVA1 | TCEAL2 | 0.743644 | 8 | 0 | 7 |
| NOVA1 | PLP1 | 0.740417 | 8 | 0 | 7 |
| NOVA1 | MEOX2 | 0.739334 | 7 | 0 | 7 |
| NOVA1 | RBPMS2 | 0.738141 | 5 | 0 | 4 |
| NOVA1 | ANO5 | 0.737171 | 5 | 0 | 5 |
| NOVA1 | RASL12 | 0.736809 | 8 | 0 | 8 |
| NOVA1 | PSIP1 | 0.73283 | 6 | 0 | 6 |
| NOVA1 | RBM24 | 0.7308 | 5 | 0 | 5 |
For details and further investigation, click here
