| Full name: chromosome 3 open reading frame 70 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 3q27.2 | ||
| Entrez ID: 285382 | HGNC ID: HGNC:33731 | Ensembl Gene: ENSG00000187068 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C3orf70:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C3orf70 | 285382 | 242447_at | -2.0337 | 0.1830 | |
| GSE26886 | C3orf70 | 285382 | 242447_at | 1.1633 | 0.0930 | |
| GSE45670 | C3orf70 | 285382 | 242447_at | -2.6834 | 0.0000 | |
| GSE53622 | C3orf70 | 285382 | 20748 | -1.2947 | 0.0000 | |
| GSE53624 | C3orf70 | 285382 | 20748 | -1.0595 | 0.0000 | |
| GSE63941 | C3orf70 | 285382 | 242447_at | -0.5720 | 0.6361 | |
| GSE77861 | C3orf70 | 285382 | 242447_at | 0.4686 | 0.0724 | |
| GSE97050 | C3orf70 | 285382 | A_33_P3254811 | -0.6314 | 0.2076 | |
| SRP007169 | C3orf70 | 285382 | RNAseq | 1.4440 | 0.0485 | |
| SRP064894 | C3orf70 | 285382 | RNAseq | -0.5115 | 0.0945 | |
| SRP133303 | C3orf70 | 285382 | RNAseq | -0.5717 | 0.1606 | |
| SRP159526 | C3orf70 | 285382 | RNAseq | -0.4725 | 0.3565 | |
| SRP193095 | C3orf70 | 285382 | RNAseq | 0.6312 | 0.0186 | |
| SRP219564 | C3orf70 | 285382 | RNAseq | -0.6257 | 0.4858 | |
| TCGA | C3orf70 | 285382 | RNAseq | -0.6811 | 0.0004 |
Upregulated datasets: 1; Downregulated datasets: 3.
Survival by C3orf70 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C3orf70:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C3orf70 | 285382 | 25 | 0 | 5 | |
| GSE20123 | C3orf70 | 285382 | 25 | 0 | 5 | |
| GSE43470 | C3orf70 | 285382 | 23 | 0 | 20 | |
| GSE46452 | C3orf70 | 285382 | 19 | 1 | 39 | |
| GSE47630 | C3orf70 | 285382 | 27 | 2 | 11 | |
| GSE54993 | C3orf70 | 285382 | 1 | 19 | 50 | |
| GSE54994 | C3orf70 | 285382 | 40 | 0 | 13 | |
| GSE60625 | C3orf70 | 285382 | 0 | 6 | 5 | |
| GSE74703 | C3orf70 | 285382 | 20 | 0 | 16 | |
| GSE74704 | C3orf70 | 285382 | 17 | 0 | 3 | |
| TCGA | C3orf70 | 285382 | 77 | 0 | 19 |
Total number of gains: 274; Total number of losses: 28; Total Number of normals: 186.
Somatic mutations of C3orf70:
Generating mutation plots.
Highly correlated genes for C3orf70:
Showing top 20/972 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C3orf70 | FIBIN | 0.865623 | 3 | 0 | 3 |
| C3orf70 | BHMT2 | 0.849584 | 5 | 0 | 5 |
| C3orf70 | RNASE4 | 0.839701 | 3 | 0 | 3 |
| C3orf70 | DTNA | 0.839427 | 4 | 0 | 4 |
| C3orf70 | PDE5A | 0.838594 | 6 | 0 | 6 |
| C3orf70 | ARHGAP6 | 0.837791 | 5 | 0 | 5 |
| C3orf70 | TNS1 | 0.834899 | 6 | 0 | 6 |
| C3orf70 | LINC01279 | 0.833194 | 3 | 0 | 3 |
| C3orf70 | SLITRK3 | 0.827721 | 5 | 0 | 5 |
| C3orf70 | CYSLTR1 | 0.826485 | 5 | 0 | 5 |
| C3orf70 | PRKAR2B | 0.811813 | 7 | 0 | 7 |
| C3orf70 | CNN1 | 0.807617 | 6 | 0 | 6 |
| C3orf70 | OGN | 0.807358 | 5 | 0 | 5 |
| C3orf70 | PLN | 0.801603 | 8 | 0 | 8 |
| C3orf70 | TNFSF12 | 0.798582 | 3 | 0 | 3 |
| C3orf70 | CLIP3 | 0.79785 | 6 | 0 | 6 |
| C3orf70 | JAM2 | 0.796924 | 5 | 0 | 5 |
| C3orf70 | MEOX2 | 0.796546 | 5 | 0 | 5 |
| C3orf70 | MAMDC2 | 0.794679 | 5 | 0 | 5 |
| C3orf70 | WSCD2 | 0.78918 | 3 | 0 | 3 |
For details and further investigation, click here
