| Full name: nuclear receptor subfamily 2 group C member 1 | Alias Symbol: TR2-11 | ||
| Type: protein-coding gene | Cytoband: 12q22 | ||
| Entrez ID: 7181 | HGNC ID: HGNC:7971 | Ensembl Gene: ENSG00000120798 | OMIM ID: 601529 |
| Drug and gene relationship at DGIdb | |||
Expression of NR2C1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NR2C1 | 7181 | 204791_at | -0.1842 | 0.6425 | |
| GSE20347 | NR2C1 | 7181 | 204791_at | 0.4962 | 0.0052 | |
| GSE23400 | NR2C1 | 7181 | 210530_s_at | 0.1875 | 0.0000 | |
| GSE26886 | NR2C1 | 7181 | 204791_at | 0.0454 | 0.9281 | |
| GSE29001 | NR2C1 | 7181 | 210530_s_at | 0.3608 | 0.1617 | |
| GSE38129 | NR2C1 | 7181 | 204791_at | 0.2869 | 0.0233 | |
| GSE45670 | NR2C1 | 7181 | 204791_at | -0.0811 | 0.6487 | |
| GSE53622 | NR2C1 | 7181 | 16431 | 0.1226 | 0.1424 | |
| GSE53624 | NR2C1 | 7181 | 16431 | 0.2142 | 0.0422 | |
| GSE63941 | NR2C1 | 7181 | 204791_at | -0.5704 | 0.0699 | |
| GSE77861 | NR2C1 | 7181 | 210530_s_at | 0.1118 | 0.5115 | |
| GSE97050 | NR2C1 | 7181 | A_33_P3302220 | -0.0946 | 0.7532 | |
| SRP007169 | NR2C1 | 7181 | RNAseq | 0.5625 | 0.1202 | |
| SRP008496 | NR2C1 | 7181 | RNAseq | 0.7843 | 0.0033 | |
| SRP064894 | NR2C1 | 7181 | RNAseq | 0.2528 | 0.1727 | |
| SRP133303 | NR2C1 | 7181 | RNAseq | 0.2096 | 0.0469 | |
| SRP159526 | NR2C1 | 7181 | RNAseq | 0.0747 | 0.7754 | |
| SRP193095 | NR2C1 | 7181 | RNAseq | 0.1265 | 0.2749 | |
| SRP219564 | NR2C1 | 7181 | RNAseq | -0.2191 | 0.3408 | |
| TCGA | NR2C1 | 7181 | RNAseq | 0.0111 | 0.8519 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NR2C1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NR2C1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NR2C1 | 7181 | 4 | 2 | 24 | |
| GSE20123 | NR2C1 | 7181 | 4 | 2 | 24 | |
| GSE43470 | NR2C1 | 7181 | 3 | 0 | 40 | |
| GSE46452 | NR2C1 | 7181 | 9 | 1 | 49 | |
| GSE47630 | NR2C1 | 7181 | 9 | 1 | 30 | |
| GSE54993 | NR2C1 | 7181 | 0 | 5 | 65 | |
| GSE54994 | NR2C1 | 7181 | 4 | 1 | 48 | |
| GSE60625 | NR2C1 | 7181 | 0 | 0 | 11 | |
| GSE74703 | NR2C1 | 7181 | 3 | 0 | 33 | |
| GSE74704 | NR2C1 | 7181 | 1 | 2 | 17 | |
| TCGA | NR2C1 | 7181 | 16 | 10 | 70 |
Total number of gains: 53; Total number of losses: 24; Total Number of normals: 411.
Somatic mutations of NR2C1:
Generating mutation plots.
Highly correlated genes for NR2C1:
Showing top 20/273 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NR2C1 | EXOC8 | 0.789575 | 3 | 0 | 3 |
| NR2C1 | ZNF800 | 0.781826 | 3 | 0 | 3 |
| NR2C1 | TMEM218 | 0.77632 | 3 | 0 | 3 |
| NR2C1 | USP25 | 0.757515 | 3 | 0 | 3 |
| NR2C1 | PNPLA8 | 0.747076 | 3 | 0 | 3 |
| NR2C1 | HIBADH | 0.737786 | 3 | 0 | 3 |
| NR2C1 | USP8 | 0.734847 | 3 | 0 | 3 |
| NR2C1 | ARV1 | 0.729799 | 3 | 0 | 3 |
| NR2C1 | STYX | 0.718217 | 3 | 0 | 3 |
| NR2C1 | UBE2E2 | 0.713048 | 3 | 0 | 3 |
| NR2C1 | SNX13 | 0.711845 | 3 | 0 | 3 |
| NR2C1 | OSGEPL1 | 0.704674 | 3 | 0 | 3 |
| NR2C1 | MORC4 | 0.701109 | 3 | 0 | 3 |
| NR2C1 | MAU2 | 0.700681 | 3 | 0 | 3 |
| NR2C1 | SLC30A5 | 0.699079 | 4 | 0 | 3 |
| NR2C1 | GIN1 | 0.696184 | 3 | 0 | 3 |
| NR2C1 | KIAA1143 | 0.694006 | 4 | 0 | 4 |
| NR2C1 | NOM1 | 0.691337 | 3 | 0 | 3 |
| NR2C1 | TNRC6A | 0.688633 | 4 | 0 | 3 |
| NR2C1 | WDR36 | 0.685425 | 3 | 0 | 3 |
For details and further investigation, click here
