| Full name: neurogranin | Alias Symbol: RC3 | ||
| Type: protein-coding gene | Cytoband: 11q24.2 | ||
| Entrez ID: 4900 | HGNC ID: HGNC:8000 | Ensembl Gene: ENSG00000154146 | OMIM ID: 602350 |
| Drug and gene relationship at DGIdb | |||
Expression of NRGN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NRGN | 4900 | 204081_at | 0.0630 | 0.9214 | |
| GSE20347 | NRGN | 4900 | 204081_at | 0.0485 | 0.5079 | |
| GSE23400 | NRGN | 4900 | 204081_at | -0.1527 | 0.0001 | |
| GSE26886 | NRGN | 4900 | 204081_at | -0.0787 | 0.7003 | |
| GSE29001 | NRGN | 4900 | 204081_at | -0.1787 | 0.2752 | |
| GSE38129 | NRGN | 4900 | 204081_at | -0.2343 | 0.2531 | |
| GSE45670 | NRGN | 4900 | 204081_at | 0.0076 | 0.9686 | |
| GSE53622 | NRGN | 4900 | 39581 | -0.4948 | 0.0000 | |
| GSE53624 | NRGN | 4900 | 39581 | -0.2289 | 0.0357 | |
| GSE63941 | NRGN | 4900 | 204081_at | -0.0070 | 0.9926 | |
| GSE77861 | NRGN | 4900 | 204081_at | 0.0613 | 0.4597 | |
| GSE97050 | NRGN | 4900 | A_23_P116264 | 0.1948 | 0.7428 | |
| SRP064894 | NRGN | 4900 | RNAseq | 0.5542 | 0.1799 | |
| SRP133303 | NRGN | 4900 | RNAseq | -0.5709 | 0.0412 | |
| SRP159526 | NRGN | 4900 | RNAseq | 0.3883 | 0.5466 | |
| SRP219564 | NRGN | 4900 | RNAseq | 0.0226 | 0.9618 | |
| TCGA | NRGN | 4900 | RNAseq | 0.0878 | 0.5677 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by NRGN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NRGN:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NRGN | 4900 | 0 | 13 | 17 | |
| GSE20123 | NRGN | 4900 | 0 | 13 | 17 | |
| GSE43470 | NRGN | 4900 | 2 | 7 | 34 | |
| GSE46452 | NRGN | 4900 | 3 | 26 | 30 | |
| GSE47630 | NRGN | 4900 | 2 | 19 | 19 | |
| GSE54993 | NRGN | 4900 | 10 | 0 | 60 | |
| GSE54994 | NRGN | 4900 | 5 | 19 | 29 | |
| GSE60625 | NRGN | 4900 | 0 | 3 | 8 | |
| GSE74703 | NRGN | 4900 | 1 | 5 | 30 | |
| GSE74704 | NRGN | 4900 | 0 | 9 | 11 | |
| TCGA | NRGN | 4900 | 6 | 50 | 40 |
Total number of gains: 29; Total number of losses: 164; Total Number of normals: 295.
Somatic mutations of NRGN:
Generating mutation plots.
Highly correlated genes for NRGN:
Showing top 20/570 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NRGN | SMARCD1 | 0.757372 | 3 | 0 | 3 |
| NRGN | MPV17L | 0.729229 | 3 | 0 | 3 |
| NRGN | STRN4 | 0.724195 | 3 | 0 | 3 |
| NRGN | ZBTB12 | 0.719265 | 3 | 0 | 3 |
| NRGN | PHLDB1 | 0.710132 | 4 | 0 | 3 |
| NRGN | MADD | 0.708036 | 3 | 0 | 3 |
| NRGN | ZNF142 | 0.703112 | 3 | 0 | 3 |
| NRGN | SORBS3 | 0.700007 | 5 | 0 | 5 |
| NRGN | CABIN1 | 0.695817 | 4 | 0 | 4 |
| NRGN | CD151 | 0.694335 | 3 | 0 | 3 |
| NRGN | FBXO31 | 0.684615 | 4 | 0 | 3 |
| NRGN | ZNF467 | 0.67898 | 4 | 0 | 4 |
| NRGN | APOBEC3F | 0.677109 | 3 | 0 | 3 |
| NRGN | FAM167B | 0.675893 | 3 | 0 | 3 |
| NRGN | MYO7B | 0.675467 | 3 | 0 | 3 |
| NRGN | SLC12A9 | 0.675032 | 4 | 0 | 4 |
| NRGN | STAC | 0.673558 | 3 | 0 | 3 |
| NRGN | CPT1A | 0.672665 | 3 | 0 | 3 |
| NRGN | DMBT1 | 0.671209 | 3 | 0 | 3 |
| NRGN | AP4M1 | 0.669071 | 3 | 0 | 3 |
For details and further investigation, click here
