| Full name: myosin VIIB | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q14.3 | ||
| Entrez ID: 4648 | HGNC ID: HGNC:7607 | Ensembl Gene: ENSG00000169994 | OMIM ID: 606541 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MYO7B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MYO7B | 4648 | 235383_at | 0.0718 | 0.8392 | |
| GSE20347 | MYO7B | 4648 | 216662_at | -0.0654 | 0.3969 | |
| GSE23400 | MYO7B | 4648 | 216662_at | -0.1453 | 0.0001 | |
| GSE26886 | MYO7B | 4648 | 235383_at | 0.2515 | 0.0492 | |
| GSE29001 | MYO7B | 4648 | 216662_at | -0.1181 | 0.4920 | |
| GSE38129 | MYO7B | 4648 | 216662_at | -0.1469 | 0.0163 | |
| GSE45670 | MYO7B | 4648 | 235383_at | -0.1011 | 0.3283 | |
| GSE53622 | MYO7B | 4648 | 66350 | 0.1267 | 0.3450 | |
| GSE53624 | MYO7B | 4648 | 66350 | 0.0610 | 0.4922 | |
| GSE63941 | MYO7B | 4648 | 235383_at | 0.2654 | 0.1259 | |
| GSE77861 | MYO7B | 4648 | 235383_at | -0.0122 | 0.9314 | |
| GSE97050 | MYO7B | 4648 | A_23_P209799 | 0.0345 | 0.9078 | |
| SRP133303 | MYO7B | 4648 | RNAseq | -0.8833 | 0.0127 | |
| SRP159526 | MYO7B | 4648 | RNAseq | -0.9261 | 0.1448 | |
| SRP219564 | MYO7B | 4648 | RNAseq | -1.0240 | 0.1733 | |
| TCGA | MYO7B | 4648 | RNAseq | -0.7472 | 0.0671 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MYO7B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MYO7B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MYO7B | 4648 | 6 | 3 | 21 | |
| GSE20123 | MYO7B | 4648 | 6 | 3 | 21 | |
| GSE43470 | MYO7B | 4648 | 2 | 1 | 40 | |
| GSE46452 | MYO7B | 4648 | 1 | 3 | 55 | |
| GSE47630 | MYO7B | 4648 | 6 | 0 | 34 | |
| GSE54993 | MYO7B | 4648 | 0 | 6 | 64 | |
| GSE54994 | MYO7B | 4648 | 11 | 0 | 42 | |
| GSE60625 | MYO7B | 4648 | 0 | 3 | 8 | |
| GSE74703 | MYO7B | 4648 | 2 | 1 | 33 | |
| GSE74704 | MYO7B | 4648 | 3 | 1 | 16 | |
| TCGA | MYO7B | 4648 | 22 | 8 | 66 |
Total number of gains: 59; Total number of losses: 29; Total Number of normals: 400.
Somatic mutations of MYO7B:
Generating mutation plots.
Highly correlated genes for MYO7B:
Showing top 20/285 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MYO7B | MTAP | 0.699342 | 3 | 0 | 3 |
| MYO7B | SERPINA6 | 0.67863 | 3 | 0 | 3 |
| MYO7B | ART1 | 0.677054 | 3 | 0 | 3 |
| MYO7B | NRGN | 0.675467 | 3 | 0 | 3 |
| MYO7B | SLC6A3 | 0.668586 | 3 | 0 | 3 |
| MYO7B | TP53I11 | 0.665278 | 3 | 0 | 3 |
| MYO7B | KCNC3 | 0.66388 | 4 | 0 | 4 |
| MYO7B | GPR21 | 0.657715 | 5 | 0 | 3 |
| MYO7B | BRS3 | 0.654144 | 3 | 0 | 3 |
| MYO7B | CER1 | 0.636917 | 3 | 0 | 3 |
| MYO7B | HDAC7 | 0.635917 | 4 | 0 | 3 |
| MYO7B | SERINC2 | 0.630333 | 3 | 0 | 3 |
| MYO7B | CHST8 | 0.62961 | 4 | 0 | 4 |
| MYO7B | DAGLA | 0.627116 | 4 | 0 | 4 |
| MYO7B | CLDN14 | 0.624574 | 3 | 0 | 3 |
| MYO7B | SPIN2A | 0.623644 | 5 | 0 | 4 |
| MYO7B | RAC3 | 0.619157 | 3 | 0 | 3 |
| MYO7B | PDE1B | 0.618477 | 6 | 0 | 4 |
| MYO7B | ZG16 | 0.61788 | 5 | 0 | 4 |
| MYO7B | VSX1 | 0.615301 | 4 | 0 | 3 |
For details and further investigation, click here
