NAP1L5

 

Full name: nucleosome assembly protein 1 like 5 Alias Symbol: DRLM
Type: protein-coding gene Cytoband: 4q22.1
Entrez ID: 266812 HGNC ID: HGNC:19968 Ensembl Gene: ENSG00000177432 OMIM ID: 612203
Drug and gene relationship at DGIdb

 

Expression of NAP1L5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NAP1L5 266812 228063_s_at -0.2454 0.7098
GSE26886 NAP1L5 266812 228063_s_at 1.1810 0.0017
GSE45670 NAP1L5 266812 228063_s_at -0.8683 0.0453
GSE53622 NAP1L5 266812 68582 -0.7465 0.0000
GSE53624 NAP1L5 266812 68582 -0.5620 0.0000
GSE63941 NAP1L5 266812 228063_s_at -3.1591 0.0785
GSE77861 NAP1L5 266812 228063_s_at -0.3439 0.2531
GSE97050 NAP1L5 266812 A_23_P144369 0.0191 0.9732
SRP064894 NAP1L5 266812 RNAseq 0.0149 0.9458
SRP133303 NAP1L5 266812 RNAseq -0.4030 0.2154
SRP159526 NAP1L5 266812 RNAseq 0.5592 0.3211
SRP193095 NAP1L5 266812 RNAseq 0.1541 0.3551
SRP219564 NAP1L5 266812 RNAseq 0.4622 0.5397
TCGA NAP1L5 266812 RNAseq -0.4335 0.0060

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by NAP1L5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of NAP1L5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NAP1L5 266812 1 12 17
GSE20123 NAP1L5 266812 1 12 17
GSE43470 NAP1L5 266812 0 13 30
GSE46452 NAP1L5 266812 1 36 22
GSE47630 NAP1L5 266812 0 20 20
GSE54993 NAP1L5 266812 8 0 62
GSE54994 NAP1L5 266812 1 10 42
GSE60625 NAP1L5 266812 0 0 11
GSE74703 NAP1L5 266812 0 11 25
GSE74704 NAP1L5 266812 1 7 12
TCGA NAP1L5 266812 12 37 47

Total number of gains: 25; Total number of losses: 158; Total Number of normals: 305.  


 

Somatic mutations of NAP1L5:

 

Generating mutation plots.

 

Highly correlated genes for NAP1L5:

 

Showing top 20/365 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NAP1L5TOB20.79664303
NAP1L5ZNF2080.762037303
NAP1L5PIP5K1C0.75352303
NAP1L5FNIP20.723581303
NAP1L5ZNF1360.716625303
NAP1L5COL4A50.713758303
NAP1L5ISCA10.711681303
NAP1L5ZNF7840.711389303
NAP1L5ARHGAP180.710639303
NAP1L5TCEAL60.708472303
NAP1L5ST6GALNAC60.701941303
NAP1L5TNFSF120.698454303
NAP1L5TNFRSF80.69591303
NAP1L5MAP40.690792403
NAP1L5PAQR30.689793303
NAP1L5NRP20.688845303
NAP1L5TSNARE10.68759403
NAP1L5TMEM1210.687212303
NAP1L5LNP10.687025303
NAP1L5FRMD30.685137403

For details and further investigation, click here