| Full name: zinc fingers and homeoboxes 3 | Alias Symbol: KIAA0395 | ||
| Type: protein-coding gene | Cytoband: 20q12 | ||
| Entrez ID: 23051 | HGNC ID: HGNC:15935 | Ensembl Gene: ENSG00000174306 | OMIM ID: 609598 |
| Drug and gene relationship at DGIdb | |||
Expression of ZHX3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZHX3 | 23051 | 217367_s_at | 0.0573 | 0.9455 | |
| GSE20347 | ZHX3 | 23051 | 217367_s_at | -0.2258 | 0.0608 | |
| GSE23400 | ZHX3 | 23051 | 217367_s_at | -0.4189 | 0.0000 | |
| GSE26886 | ZHX3 | 23051 | 212545_s_at | 0.0563 | 0.7830 | |
| GSE29001 | ZHX3 | 23051 | 217367_s_at | -0.1829 | 0.3036 | |
| GSE38129 | ZHX3 | 23051 | 217367_s_at | -0.7605 | 0.0000 | |
| GSE45670 | ZHX3 | 23051 | 212545_s_at | -0.1431 | 0.1326 | |
| GSE53622 | ZHX3 | 23051 | 70971 | -0.7736 | 0.0000 | |
| GSE53624 | ZHX3 | 23051 | 70971 | -0.5638 | 0.0000 | |
| GSE63941 | ZHX3 | 23051 | 217367_s_at | -2.3989 | 0.0001 | |
| GSE77861 | ZHX3 | 23051 | 212545_s_at | -0.2420 | 0.0174 | |
| GSE97050 | ZHX3 | 23051 | A_33_P3342106 | -0.7009 | 0.1403 | |
| SRP007169 | ZHX3 | 23051 | RNAseq | -0.2935 | 0.4064 | |
| SRP008496 | ZHX3 | 23051 | RNAseq | 0.3156 | 0.3017 | |
| SRP064894 | ZHX3 | 23051 | RNAseq | -0.4755 | 0.0211 | |
| SRP133303 | ZHX3 | 23051 | RNAseq | -0.4882 | 0.0140 | |
| SRP159526 | ZHX3 | 23051 | RNAseq | -0.8946 | 0.0004 | |
| SRP193095 | ZHX3 | 23051 | RNAseq | -0.3174 | 0.0115 | |
| SRP219564 | ZHX3 | 23051 | RNAseq | -0.3090 | 0.5241 | |
| TCGA | ZHX3 | 23051 | RNAseq | -0.4405 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ZHX3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZHX3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZHX3 | 23051 | 13 | 1 | 16 | |
| GSE20123 | ZHX3 | 23051 | 13 | 1 | 16 | |
| GSE43470 | ZHX3 | 23051 | 13 | 0 | 30 | |
| GSE46452 | ZHX3 | 23051 | 29 | 0 | 30 | |
| GSE47630 | ZHX3 | 23051 | 24 | 0 | 16 | |
| GSE54993 | ZHX3 | 23051 | 0 | 17 | 53 | |
| GSE54994 | ZHX3 | 23051 | 24 | 0 | 29 | |
| GSE60625 | ZHX3 | 23051 | 0 | 0 | 11 | |
| GSE74703 | ZHX3 | 23051 | 10 | 0 | 26 | |
| GSE74704 | ZHX3 | 23051 | 9 | 0 | 11 | |
| TCGA | ZHX3 | 23051 | 45 | 5 | 46 |
Total number of gains: 180; Total number of losses: 24; Total Number of normals: 284.
Somatic mutations of ZHX3:
Generating mutation plots.
Highly correlated genes for ZHX3:
Showing top 20/747 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZHX3 | RUNX1T1 | 0.74393 | 3 | 0 | 3 |
| ZHX3 | TCF21 | 0.726548 | 5 | 0 | 5 |
| ZHX3 | CELF2 | 0.718792 | 5 | 0 | 5 |
| ZHX3 | MAP1A | 0.718139 | 7 | 0 | 6 |
| ZHX3 | FLNC | 0.716727 | 7 | 0 | 6 |
| ZHX3 | MYOCD | 0.705192 | 4 | 0 | 4 |
| ZHX3 | ITGA7 | 0.694366 | 5 | 0 | 5 |
| ZHX3 | ZNF347 | 0.693938 | 3 | 0 | 3 |
| ZHX3 | ITGA1 | 0.690383 | 6 | 0 | 6 |
| ZHX3 | NFASC | 0.68971 | 7 | 0 | 6 |
| ZHX3 | STARD13 | 0.685798 | 6 | 0 | 6 |
| ZHX3 | ARF4 | 0.685563 | 3 | 0 | 3 |
| ZHX3 | IGIP | 0.684843 | 4 | 0 | 4 |
| ZHX3 | RCAN2 | 0.684655 | 7 | 0 | 6 |
| ZHX3 | RHOBTB2 | 0.682604 | 3 | 0 | 3 |
| ZHX3 | NRP2 | 0.681349 | 4 | 0 | 3 |
| ZHX3 | RASL12 | 0.6759 | 6 | 0 | 5 |
| ZHX3 | PRICKLE2 | 0.673311 | 5 | 0 | 4 |
| ZHX3 | ZNF382 | 0.673217 | 4 | 0 | 3 |
| ZHX3 | SLIT3 | 0.673174 | 6 | 0 | 6 |
For details and further investigation, click here
