| Full name: solute carrier family 25 member 21 | Alias Symbol: ODC1|ODC | ||
| Type: protein-coding gene | Cytoband: 14q13.3 | ||
| Entrez ID: 89874 | HGNC ID: HGNC:14411 | Ensembl Gene: ENSG00000183032 | OMIM ID: 607571 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC25A21:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC25A21 | 89874 | 220474_at | 0.2169 | 0.7241 | |
| GSE20347 | SLC25A21 | 89874 | 220474_at | -0.1271 | 0.2183 | |
| GSE23400 | SLC25A21 | 89874 | 220474_at | -0.0631 | 0.0042 | |
| GSE26886 | SLC25A21 | 89874 | 220474_at | 0.3185 | 0.3887 | |
| GSE29001 | SLC25A21 | 89874 | 220474_at | -0.2308 | 0.3230 | |
| GSE38129 | SLC25A21 | 89874 | 220474_at | -0.0986 | 0.3230 | |
| GSE45670 | SLC25A21 | 89874 | 220474_at | -0.4744 | 0.0097 | |
| GSE53622 | SLC25A21 | 89874 | 84230 | -1.6855 | 0.0000 | |
| GSE53624 | SLC25A21 | 89874 | 84230 | -1.2932 | 0.0000 | |
| GSE63941 | SLC25A21 | 89874 | 220474_at | 1.2595 | 0.2095 | |
| GSE77861 | SLC25A21 | 89874 | 220474_at | 0.0465 | 0.7194 | |
| GSE97050 | SLC25A21 | A_21_P0000084 | -0.9910 | 0.0830 | ||
| SRP007169 | SLC25A21 | 89874 | RNAseq | -0.2152 | 0.7171 | |
| SRP064894 | SLC25A21 | 89874 | RNAseq | -1.9332 | 0.0000 | |
| SRP133303 | SLC25A21 | 89874 | RNAseq | -0.4977 | 0.3749 | |
| SRP159526 | SLC25A21 | 89874 | RNAseq | -1.2255 | 0.0597 | |
| SRP219564 | SLC25A21 | 89874 | RNAseq | -1.8655 | 0.0019 | |
| TCGA | SLC25A21 | 89874 | RNAseq | -0.3320 | 0.2791 |
Upregulated datasets: 0; Downregulated datasets: 4.
Survival by SLC25A21 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC25A21:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC25A21 | 89874 | 11 | 4 | 15 | |
| GSE20123 | SLC25A21 | 89874 | 12 | 4 | 14 | |
| GSE43470 | SLC25A21 | 89874 | 9 | 2 | 32 | |
| GSE46452 | SLC25A21 | 89874 | 18 | 2 | 39 | |
| GSE47630 | SLC25A21 | 89874 | 11 | 10 | 19 | |
| GSE54993 | SLC25A21 | 89874 | 3 | 11 | 56 | |
| GSE54994 | SLC25A21 | 89874 | 19 | 5 | 29 | |
| GSE60625 | SLC25A21 | 89874 | 0 | 2 | 9 | |
| GSE74703 | SLC25A21 | 89874 | 8 | 2 | 26 | |
| GSE74704 | SLC25A21 | 89874 | 6 | 3 | 11 | |
| TCGA | SLC25A21 | 89874 | 37 | 15 | 44 |
Total number of gains: 134; Total number of losses: 60; Total Number of normals: 294.
Somatic mutations of SLC25A21:
Generating mutation plots.
Highly correlated genes for SLC25A21:
Showing top 20/123 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC25A21 | TMEM135 | 0.729682 | 3 | 0 | 3 |
| SLC25A21 | RPL36AL | 0.727092 | 3 | 0 | 3 |
| SLC25A21 | FAM168A | 0.722361 | 3 | 0 | 3 |
| SLC25A21 | AGR3 | 0.71253 | 3 | 0 | 3 |
| SLC25A21 | LUC7L2 | 0.705746 | 3 | 0 | 3 |
| SLC25A21 | IL34 | 0.699669 | 3 | 0 | 3 |
| SLC25A21 | NUBPL | 0.676811 | 4 | 0 | 3 |
| SLC25A21 | LYSMD1 | 0.669845 | 3 | 0 | 3 |
| SLC25A21 | DIS3L | 0.667539 | 3 | 0 | 3 |
| SLC25A21 | IRAK1BP1 | 0.665329 | 4 | 0 | 3 |
| SLC25A21 | TM7SF2 | 0.650189 | 4 | 0 | 3 |
| SLC25A21 | DDI2 | 0.641157 | 3 | 0 | 3 |
| SLC25A21 | CYP4B1 | 0.634892 | 3 | 0 | 3 |
| SLC25A21 | PKNOX1 | 0.633236 | 3 | 0 | 3 |
| SLC25A21 | PLEKHH2 | 0.632004 | 3 | 0 | 3 |
| SLC25A21 | N4BP3 | 0.629806 | 4 | 0 | 3 |
| SLC25A21 | FAM161A | 0.622041 | 3 | 0 | 3 |
| SLC25A21 | KLF8 | 0.621036 | 4 | 0 | 3 |
| SLC25A21 | OTUD7B | 0.620215 | 3 | 0 | 3 |
| SLC25A21 | TMEM127 | 0.619685 | 4 | 0 | 3 |
For details and further investigation, click here
