| Full name: neurexophilin and PC-esterase domain family member 3 | Alias Symbol: MGC15606 | ||
| Type: protein-coding gene | Cytoband: 3q12.3 | ||
| Entrez ID: 91775 | HGNC ID: HGNC:28238 | Ensembl Gene: ENSG00000144815 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of NXPE3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NXPE3 | 91775 | 243011_at | 0.3815 | 0.3832 | |
| GSE20347 | NXPE3 | 91775 | 217540_at | 0.5847 | 0.0000 | |
| GSE23400 | NXPE3 | 91775 | 217540_at | 0.1529 | 0.0000 | |
| GSE26886 | NXPE3 | 91775 | 243011_at | 0.7802 | 0.0040 | |
| GSE29001 | NXPE3 | 91775 | 217540_at | 1.1375 | 0.0002 | |
| GSE38129 | NXPE3 | 91775 | 217540_at | 0.6822 | 0.0011 | |
| GSE45670 | NXPE3 | 91775 | 235030_at | -0.3069 | 0.5358 | |
| GSE53622 | NXPE3 | 91775 | 10525 | 0.1544 | 0.3280 | |
| GSE53624 | NXPE3 | 91775 | 10525 | 0.5247 | 0.0011 | |
| GSE63941 | NXPE3 | 91775 | 243011_at | 1.0122 | 0.1388 | |
| GSE77861 | NXPE3 | 91775 | 243011_at | 0.3082 | 0.1638 | |
| SRP007169 | NXPE3 | 91775 | RNAseq | 2.8984 | 0.0000 | |
| SRP008496 | NXPE3 | 91775 | RNAseq | 3.0328 | 0.0000 | |
| SRP064894 | NXPE3 | 91775 | RNAseq | 0.9929 | 0.0000 | |
| SRP133303 | NXPE3 | 91775 | RNAseq | 0.1561 | 0.0929 | |
| SRP159526 | NXPE3 | 91775 | RNAseq | 1.1377 | 0.0058 | |
| SRP193095 | NXPE3 | 91775 | RNAseq | 1.0637 | 0.0000 | |
| SRP219564 | NXPE3 | 91775 | RNAseq | -0.0398 | 0.9335 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by NXPE3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of NXPE3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NXPE3 | 91775 | 18 | 1 | 11 | |
| GSE20123 | NXPE3 | 91775 | 17 | 1 | 12 | |
| GSE43470 | NXPE3 | 91775 | 17 | 1 | 25 | |
| GSE46452 | NXPE3 | 91775 | 12 | 6 | 41 | |
| GSE47630 | NXPE3 | 91775 | 16 | 6 | 18 | |
| GSE54993 | NXPE3 | 91775 | 2 | 5 | 63 | |
| GSE54994 | NXPE3 | 91775 | 27 | 5 | 21 | |
| GSE60625 | NXPE3 | 91775 | 0 | 6 | 5 | |
| GSE74703 | NXPE3 | 91775 | 14 | 1 | 21 | |
| GSE74704 | NXPE3 | 91775 | 14 | 1 | 5 | |
| TCGA | NXPE3 | 91775 | 47 | 10 | 39 |
Total number of gains: 184; Total number of losses: 43; Total Number of normals: 261.
Somatic mutations of NXPE3:
Generating mutation plots.
Highly correlated genes for NXPE3:
Showing top 20/625 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NXPE3 | ANXA10 | 0.738284 | 3 | 0 | 3 |
| NXPE3 | TP53I13 | 0.691697 | 3 | 0 | 3 |
| NXPE3 | CHST3 | 0.683876 | 5 | 0 | 4 |
| NXPE3 | ZNF532 | 0.68234 | 6 | 0 | 4 |
| NXPE3 | SUGCT | 0.674904 | 4 | 0 | 4 |
| NXPE3 | PMEPA1 | 0.671312 | 6 | 0 | 5 |
| NXPE3 | TMEM185B | 0.666645 | 5 | 0 | 5 |
| NXPE3 | PLEKHA3 | 0.660656 | 5 | 0 | 5 |
| NXPE3 | MSN | 0.660228 | 6 | 0 | 5 |
| NXPE3 | FAM219A | 0.658701 | 3 | 0 | 3 |
| NXPE3 | TCEAL3 | 0.653135 | 3 | 0 | 3 |
| NXPE3 | NFE2L1 | 0.651943 | 6 | 0 | 5 |
| NXPE3 | ZFPM1 | 0.651894 | 3 | 0 | 3 |
| NXPE3 | FADS3 | 0.651111 | 6 | 0 | 5 |
| NXPE3 | EDIL3 | 0.65037 | 4 | 0 | 3 |
| NXPE3 | IKBKG | 0.648745 | 4 | 0 | 4 |
| NXPE3 | SERPINH1 | 0.648737 | 7 | 0 | 5 |
| NXPE3 | RUNX1-IT1 | 0.648064 | 4 | 0 | 3 |
| NXPE3 | IFITM3 | 0.643486 | 6 | 0 | 5 |
| NXPE3 | PLEK2 | 0.641249 | 3 | 0 | 3 |
For details and further investigation, click here
