| Full name: moesin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: Xq12 | ||
| Entrez ID: 4478 | HGNC ID: HGNC:7373 | Ensembl Gene: ENSG00000147065 | OMIM ID: 309845 |
| Drug and gene relationship at DGIdb | |||
MSN involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04670 | Leukocyte transendothelial migration | |
| hsa04810 | Regulation of actin cytoskeleton | |
| hsa05205 | Proteoglycans in cancer |
Expression of MSN:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MSN | 4478 | 200600_at | 0.6150 | 0.3377 | |
| GSE20347 | MSN | 4478 | 200600_at | 1.0001 | 0.0001 | |
| GSE23400 | MSN | 4478 | 200600_at | 1.1144 | 0.0000 | |
| GSE26886 | MSN | 4478 | 200600_at | 1.2090 | 0.0007 | |
| GSE29001 | MSN | 4478 | 200600_at | 1.0615 | 0.0007 | |
| GSE38129 | MSN | 4478 | 200600_at | 0.9078 | 0.0000 | |
| GSE45670 | MSN | 4478 | 200600_at | 1.0788 | 0.0001 | |
| GSE53622 | MSN | 4478 | 78940 | 1.0674 | 0.0000 | |
| GSE53624 | MSN | 4478 | 45853 | 1.2523 | 0.0000 | |
| GSE63941 | MSN | 4478 | 200600_at | -1.4581 | 0.3780 | |
| GSE77861 | MSN | 4478 | 200600_at | 1.3737 | 0.0115 | |
| GSE97050 | MSN | 4478 | A_23_P73589 | 0.7428 | 0.0782 | |
| SRP007169 | MSN | 4478 | RNAseq | 1.1037 | 0.0491 | |
| SRP008496 | MSN | 4478 | RNAseq | 1.0400 | 0.0022 | |
| SRP064894 | MSN | 4478 | RNAseq | 1.4653 | 0.0000 | |
| SRP133303 | MSN | 4478 | RNAseq | 1.5435 | 0.0000 | |
| SRP159526 | MSN | 4478 | RNAseq | 0.6994 | 0.0006 | |
| SRP193095 | MSN | 4478 | RNAseq | 1.8386 | 0.0000 | |
| SRP219564 | MSN | 4478 | RNAseq | 1.0391 | 0.0203 | |
| TCGA | MSN | 4478 | RNAseq | 0.2969 | 0.0000 |
Upregulated datasets: 14; Downregulated datasets: 0.
Survival by MSN expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MSN:
No record found for this gene.
Somatic mutations of MSN:
Generating mutation plots.
Highly correlated genes for MSN:
Showing top 20/1878 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MSN | LPCAT1 | 0.819777 | 11 | 0 | 11 |
| MSN | TMC8 | 0.818143 | 3 | 0 | 3 |
| MSN | NXN | 0.796913 | 3 | 0 | 3 |
| MSN | GNG10 | 0.792431 | 3 | 0 | 3 |
| MSN | FBLIM1 | 0.783016 | 7 | 0 | 6 |
| MSN | SLC39A3 | 0.776152 | 3 | 0 | 3 |
| MSN | ARPC1B | 0.770501 | 11 | 0 | 10 |
| MSN | RILPL1 | 0.770481 | 3 | 0 | 3 |
| MSN | B3GNT9 | 0.768137 | 7 | 0 | 7 |
| MSN | TWIST2 | 0.766971 | 3 | 0 | 3 |
| MSN | FADS1 | 0.76641 | 3 | 0 | 3 |
| MSN | ENAH | 0.762688 | 12 | 0 | 11 |
| MSN | WDR4 | 0.759534 | 3 | 0 | 3 |
| MSN | WDR54 | 0.753133 | 7 | 0 | 7 |
| MSN | TUBA1B | 0.750304 | 7 | 0 | 7 |
| MSN | SNX10 | 0.749143 | 10 | 0 | 10 |
| MSN | XPR1 | 0.747786 | 7 | 0 | 7 |
| MSN | CDK6 | 0.745355 | 7 | 0 | 7 |
| MSN | DTX3L | 0.739862 | 5 | 0 | 5 |
| MSN | NUS1 | 0.737363 | 5 | 0 | 5 |
For details and further investigation, click here
