| Full name: carbohydrate sulfotransferase 3 | Alias Symbol: C6ST|C6ST1 | ||
| Type: protein-coding gene | Cytoband: 10q22.1 | ||
| Entrez ID: 9469 | HGNC ID: HGNC:1971 | Ensembl Gene: ENSG00000122863 | OMIM ID: 603799 |
| Drug and gene relationship at DGIdb | |||
Expression of CHST3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CHST3 | 9469 | 209834_at | 0.3174 | 0.7192 | |
| GSE20347 | CHST3 | 9469 | 209834_at | 0.6479 | 0.0035 | |
| GSE23400 | CHST3 | 9469 | 209834_at | 0.2825 | 0.0000 | |
| GSE26886 | CHST3 | 9469 | 209834_at | 0.9855 | 0.0004 | |
| GSE29001 | CHST3 | 9469 | 209834_at | 0.6510 | 0.0074 | |
| GSE38129 | CHST3 | 9469 | 32094_at | 0.4037 | 0.0109 | |
| GSE45670 | CHST3 | 9469 | 209834_at | 0.2266 | 0.2545 | |
| GSE63941 | CHST3 | 9469 | 209834_at | -0.6764 | 0.0960 | |
| GSE77861 | CHST3 | 9469 | 209834_at | 0.4281 | 0.1524 | |
| GSE97050 | CHST3 | 9469 | A_24_P269779 | 0.3252 | 0.2576 | |
| SRP007169 | CHST3 | 9469 | RNAseq | 1.5733 | 0.0005 | |
| SRP008496 | CHST3 | 9469 | RNAseq | 1.8918 | 0.0000 | |
| SRP064894 | CHST3 | 9469 | RNAseq | 0.3173 | 0.1901 | |
| SRP133303 | CHST3 | 9469 | RNAseq | 1.0348 | 0.0064 | |
| SRP159526 | CHST3 | 9469 | RNAseq | 0.8245 | 0.0007 | |
| SRP193095 | CHST3 | 9469 | RNAseq | 1.3442 | 0.0000 | |
| SRP219564 | CHST3 | 9469 | RNAseq | 0.2362 | 0.6640 | |
| TCGA | CHST3 | 9469 | RNAseq | -0.1720 | 0.0309 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by CHST3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of CHST3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CHST3 | 9469 | 3 | 4 | 23 | |
| GSE20123 | CHST3 | 9469 | 3 | 3 | 24 | |
| GSE43470 | CHST3 | 9469 | 1 | 8 | 34 | |
| GSE46452 | CHST3 | 9469 | 0 | 11 | 48 | |
| GSE47630 | CHST3 | 9469 | 2 | 14 | 24 | |
| GSE54993 | CHST3 | 9469 | 7 | 0 | 63 | |
| GSE54994 | CHST3 | 9469 | 2 | 11 | 40 | |
| GSE60625 | CHST3 | 9469 | 0 | 0 | 11 | |
| GSE74703 | CHST3 | 9469 | 1 | 5 | 30 | |
| GSE74704 | CHST3 | 9469 | 2 | 1 | 17 | |
| TCGA | CHST3 | 9469 | 11 | 23 | 62 |
Total number of gains: 32; Total number of losses: 80; Total Number of normals: 376.
Somatic mutations of CHST3:
Generating mutation plots.
Highly correlated genes for CHST3:
Showing top 20/971 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CHST3 | UCN | 0.834387 | 3 | 0 | 3 |
| CHST3 | CRTC2 | 0.784077 | 3 | 0 | 3 |
| CHST3 | ZFP90 | 0.773897 | 3 | 0 | 3 |
| CHST3 | MSTO1 | 0.757284 | 3 | 0 | 3 |
| CHST3 | TMEM173 | 0.756676 | 3 | 0 | 3 |
| CHST3 | UBQLN4 | 0.747571 | 3 | 0 | 3 |
| CHST3 | UBIAD1 | 0.745272 | 3 | 0 | 3 |
| CHST3 | CPT1A | 0.745117 | 4 | 0 | 4 |
| CHST3 | UCP2 | 0.743954 | 3 | 0 | 3 |
| CHST3 | USP42 | 0.740481 | 4 | 0 | 4 |
| CHST3 | ELP2 | 0.739664 | 3 | 0 | 3 |
| CHST3 | ZC3H18 | 0.738681 | 3 | 0 | 3 |
| CHST3 | SPSB2 | 0.736453 | 3 | 0 | 3 |
| CHST3 | SMYD2 | 0.7363 | 3 | 0 | 3 |
| CHST3 | MAD2L2 | 0.730498 | 3 | 0 | 3 |
| CHST3 | EGFR | 0.725451 | 3 | 0 | 3 |
| CHST3 | PPP1R35 | 0.724496 | 3 | 0 | 3 |
| CHST3 | MRPS26 | 0.723693 | 3 | 0 | 3 |
| CHST3 | NPHP3 | 0.717788 | 3 | 0 | 3 |
| CHST3 | CPLX1 | 0.715307 | 3 | 0 | 3 |
For details and further investigation, click here
