| Full name: transmembrane protein 158 (gene/pseudogene) | Alias Symbol: RIS1|p40BBp | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 25907 | HGNC ID: HGNC:30293 | Ensembl Gene: ENSG00000249992 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM158:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM158 | 25907 | 213338_at | -0.7243 | 0.5065 | |
| GSE20347 | TMEM158 | 25907 | 213338_at | 1.7529 | 0.0000 | |
| GSE23400 | TMEM158 | 25907 | 213338_at | 0.7543 | 0.0000 | |
| GSE26886 | TMEM158 | 25907 | 213338_at | 2.4468 | 0.0002 | |
| GSE29001 | TMEM158 | 25907 | 213338_at | 1.4687 | 0.0048 | |
| GSE38129 | TMEM158 | 25907 | 213338_at | 1.5720 | 0.0000 | |
| GSE45670 | TMEM158 | 25907 | 213338_at | -0.3234 | 0.6691 | |
| GSE53622 | TMEM158 | 25907 | 120053 | 0.4359 | 0.0133 | |
| GSE53624 | TMEM158 | 25907 | 120053 | 0.5441 | 0.0002 | |
| GSE63941 | TMEM158 | 25907 | 213338_at | -3.6367 | 0.0049 | |
| GSE77861 | TMEM158 | 25907 | 213338_at | 2.4258 | 0.0017 | |
| GSE97050 | TMEM158 | 25907 | A_23_P369899 | 0.8464 | 0.2434 | |
| SRP007169 | TMEM158 | 25907 | RNAseq | 4.0824 | 0.0000 | |
| SRP008496 | TMEM158 | 25907 | RNAseq | 5.2545 | 0.0000 | |
| SRP064894 | TMEM158 | 25907 | RNAseq | -1.3183 | 0.0001 | |
| SRP133303 | TMEM158 | 25907 | RNAseq | 0.8145 | 0.0726 | |
| SRP159526 | TMEM158 | 25907 | RNAseq | 0.8505 | 0.1690 | |
| SRP219564 | TMEM158 | 25907 | RNAseq | -1.5374 | 0.0177 | |
| TCGA | TMEM158 | 25907 | RNAseq | 0.6851 | 0.0000 |
Upregulated datasets: 7; Downregulated datasets: 3.
Survival by TMEM158 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TMEM158:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM158 | 25907 | 0 | 16 | 14 | |
| GSE20123 | TMEM158 | 25907 | 0 | 17 | 13 | |
| GSE43470 | TMEM158 | 25907 | 0 | 20 | 23 | |
| GSE46452 | TMEM158 | 25907 | 2 | 17 | 40 | |
| GSE47630 | TMEM158 | 25907 | 1 | 24 | 15 | |
| GSE54993 | TMEM158 | 25907 | 7 | 2 | 61 | |
| GSE54994 | TMEM158 | 25907 | 0 | 36 | 17 | |
| GSE60625 | TMEM158 | 25907 | 5 | 0 | 6 | |
| GSE74703 | TMEM158 | 25907 | 0 | 15 | 21 | |
| GSE74704 | TMEM158 | 25907 | 0 | 12 | 8 | |
| TCGA | TMEM158 | 25907 | 1 | 75 | 20 |
Total number of gains: 16; Total number of losses: 234; Total Number of normals: 238.
Somatic mutations of TMEM158:
Generating mutation plots.
Highly correlated genes for TMEM158:
Showing top 20/791 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM158 | MICAL1 | 0.759066 | 3 | 0 | 3 |
| TMEM158 | OAF | 0.734232 | 3 | 0 | 3 |
| TMEM158 | NUDT18 | 0.733077 | 3 | 0 | 3 |
| TMEM158 | BRAT1 | 0.722061 | 4 | 0 | 4 |
| TMEM158 | DPP4 | 0.719785 | 4 | 0 | 4 |
| TMEM158 | LTBR | 0.711535 | 3 | 0 | 3 |
| TMEM158 | C20orf194 | 0.70854 | 3 | 0 | 3 |
| TMEM158 | TUBA1C | 0.702007 | 3 | 0 | 3 |
| TMEM158 | COX7A1 | 0.697982 | 3 | 0 | 3 |
| TMEM158 | RWDD2A | 0.694775 | 3 | 0 | 3 |
| TMEM158 | CD99L2 | 0.694533 | 3 | 0 | 3 |
| TMEM158 | MTCL1 | 0.689072 | 7 | 0 | 6 |
| TMEM158 | DOK6 | 0.686297 | 3 | 0 | 3 |
| TMEM158 | TMEM184B | 0.686127 | 7 | 0 | 6 |
| TMEM158 | DENND3 | 0.68471 | 3 | 0 | 3 |
| TMEM158 | PRTFDC1 | 0.68419 | 3 | 0 | 3 |
| TMEM158 | KIAA0895L | 0.681611 | 3 | 0 | 3 |
| TMEM158 | FGF1 | 0.679823 | 4 | 0 | 3 |
| TMEM158 | A1BG | 0.679264 | 3 | 0 | 3 |
| TMEM158 | STRADA | 0.677265 | 4 | 0 | 4 |
For details and further investigation, click here
