| Full name: oligodendrocyte transcription factor 2 | Alias Symbol: RACK17|OLIGO2|bHLHe19 | ||
| Type: protein-coding gene | Cytoband: 21q22.11 | ||
| Entrez ID: 10215 | HGNC ID: HGNC:9398 | Ensembl Gene: ENSG00000205927 | OMIM ID: 606386 |
| Drug and gene relationship at DGIdb | |||
Expression of OLIG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OLIG2 | 10215 | 213824_at | -0.1651 | 0.4424 | |
| GSE20347 | OLIG2 | 10215 | 213824_at | -0.1167 | 0.0896 | |
| GSE23400 | OLIG2 | 10215 | 213825_at | -0.0806 | 0.0007 | |
| GSE26886 | OLIG2 | 10215 | 213824_at | 0.1089 | 0.2920 | |
| GSE29001 | OLIG2 | 10215 | 213825_at | -0.0387 | 0.7885 | |
| GSE38129 | OLIG2 | 10215 | 213825_at | -0.0171 | 0.7861 | |
| GSE45670 | OLIG2 | 10215 | 213824_at | -0.0180 | 0.8830 | |
| GSE53622 | OLIG2 | 10215 | 38221 | -0.4497 | 0.0028 | |
| GSE53624 | OLIG2 | 10215 | 38221 | -1.3413 | 0.0000 | |
| GSE63941 | OLIG2 | 10215 | 213824_at | 0.0604 | 0.7787 | |
| GSE77861 | OLIG2 | 10215 | 213825_at | 0.1210 | 0.2314 | |
| TCGA | OLIG2 | 10215 | RNAseq | 1.4122 | 0.2535 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by OLIG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OLIG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OLIG2 | 10215 | 2 | 7 | 21 | |
| GSE20123 | OLIG2 | 10215 | 2 | 8 | 20 | |
| GSE43470 | OLIG2 | 10215 | 3 | 9 | 31 | |
| GSE46452 | OLIG2 | 10215 | 1 | 21 | 37 | |
| GSE47630 | OLIG2 | 10215 | 6 | 17 | 17 | |
| GSE54993 | OLIG2 | 10215 | 9 | 1 | 60 | |
| GSE54994 | OLIG2 | 10215 | 1 | 9 | 43 | |
| GSE60625 | OLIG2 | 10215 | 0 | 0 | 11 | |
| GSE74703 | OLIG2 | 10215 | 3 | 6 | 27 | |
| GSE74704 | OLIG2 | 10215 | 1 | 4 | 15 | |
| TCGA | OLIG2 | 10215 | 9 | 35 | 52 |
Total number of gains: 37; Total number of losses: 117; Total Number of normals: 334.
Somatic mutations of OLIG2:
Generating mutation plots.
Highly correlated genes for OLIG2:
Showing top 20/208 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OLIG2 | CCDC82 | 0.719108 | 3 | 0 | 3 |
| OLIG2 | CACNA1H | 0.708277 | 3 | 0 | 3 |
| OLIG2 | ABCC9 | 0.691874 | 3 | 0 | 3 |
| OLIG2 | SLN | 0.658658 | 3 | 0 | 3 |
| OLIG2 | ADH1A | 0.65251 | 3 | 0 | 3 |
| OLIG2 | KCNJ3 | 0.646671 | 3 | 0 | 3 |
| OLIG2 | CCZ1 | 0.645409 | 3 | 0 | 3 |
| OLIG2 | ADRA2B | 0.640652 | 4 | 0 | 3 |
| OLIG2 | LINC00950 | 0.637648 | 3 | 0 | 3 |
| OLIG2 | PYGB | 0.627901 | 3 | 0 | 3 |
| OLIG2 | PDE1C | 0.623133 | 4 | 0 | 3 |
| OLIG2 | KIR2DS3 | 0.620989 | 4 | 0 | 4 |
| OLIG2 | CBLN1 | 0.620931 | 3 | 0 | 3 |
| OLIG2 | DCX | 0.620786 | 4 | 0 | 4 |
| OLIG2 | TBX5 | 0.619644 | 4 | 0 | 3 |
| OLIG2 | BRINP2 | 0.617923 | 3 | 0 | 3 |
| OLIG2 | GRIN2A | 0.617175 | 4 | 0 | 3 |
| OLIG2 | ATP2B4 | 0.61565 | 3 | 0 | 3 |
| OLIG2 | PSG9 | 0.614397 | 3 | 0 | 3 |
| OLIG2 | GRIP2 | 0.611937 | 4 | 0 | 4 |
For details and further investigation, click here
