ABCC9

 

Full name: ATP binding cassette subfamily C member 9 Alias Symbol: SUR2|CMD1O
Type: protein-coding gene Cytoband: 12p12.1
Entrez ID: 10060 HGNC ID: HGNC:60 Ensembl Gene: ENSG00000069431 OMIM ID: 601439
Drug and gene relationship at DGIdb

 

Expression of ABCC9:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ABCC9 10060 208562_s_at -0.4558 0.3774
GSE20347 ABCC9 10060 208562_s_at 0.0589 0.3106
GSE23400 ABCC9 10060 208462_s_at -0.0694 0.1203
GSE26886 ABCC9 10060 208462_s_at -0.0951 0.5282
GSE29001 ABCC9 10060 208462_s_at -0.2348 0.1835
GSE38129 ABCC9 10060 208562_s_at -0.1155 0.1584
GSE45670 ABCC9 10060 1557374_at -0.3931 0.0191
GSE53622 ABCC9 10060 135759 -0.6984 0.0002
GSE53624 ABCC9 10060 135759 -0.5228 0.0037
GSE63941 ABCC9 10060 208562_s_at -0.2349 0.1053
GSE77861 ABCC9 10060 208462_s_at -0.0492 0.6128
GSE97050 ABCC9 10060 A_23_P368691 0.0423 0.9601
SRP007169 ABCC9 10060 RNAseq 1.4804 0.0005
SRP008496 ABCC9 10060 RNAseq 2.2149 0.0000
SRP064894 ABCC9 10060 RNAseq 0.9595 0.0014
SRP133303 ABCC9 10060 RNAseq -0.5400 0.0031
SRP159526 ABCC9 10060 RNAseq 0.3296 0.5581
SRP193095 ABCC9 10060 RNAseq 0.5392 0.0001
SRP219564 ABCC9 10060 RNAseq 0.4415 0.6307
TCGA ABCC9 10060 RNAseq -0.6689 0.0007

Upregulated datasets: 2; Downregulated datasets: 0.  


 

Survival by ABCC9 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ABCC9:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ABCC9 10060 10 1 19
GSE20123 ABCC9 10060 10 1 19
GSE43470 ABCC9 10060 9 4 30
GSE46452 ABCC9 10060 10 1 48
GSE47630 ABCC9 10060 14 1 25
GSE54993 ABCC9 10060 1 9 60
GSE54994 ABCC9 10060 11 2 40
GSE60625 ABCC9 10060 0 1 10
GSE74703 ABCC9 10060 9 3 24
GSE74704 ABCC9 10060 6 1 13
TCGA ABCC9 10060 43 5 48

Total number of gains: 123; Total number of losses: 29; Total Number of normals: 336.  


 

Somatic mutations of ABCC9:

 

Generating mutation plots.

 

Highly correlated genes for ABCC9:

 

Showing top 20/860 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ABCC9FAM124A0.79501404
ABCC9TNFSF120.788468303
ABCC9LRFN50.765394505
ABCC9RHOJ0.75273504
ABCC9TCEAL60.737286303
ABCC9DACT30.722977505
ABCC9PREX20.71853606
ABCC9CBL0.718124303
ABCC9CHD20.71764303
ABCC9FRAS10.715705303
ABCC9C1QTNF20.714835404
ABCC9MRGPRF0.712134605
ABCC9KCNJ80.711738606
ABCC9FAM49A0.710895303
ABCC9RBPMS20.710297505
ABCC9GNPDA20.708204404
ABCC9SMIM100.707011505
ABCC9ASB50.701553505
ABCC9PDE3A0.699817706
ABCC9ARHGAP310.698544404

For details and further investigation, click here