| Full name: transmembrane protein 59 like | Alias Symbol: BSMAP | ||
| Type: protein-coding gene | Cytoband: 19p12 | ||
| Entrez ID: 25789 | HGNC ID: HGNC:13237 | Ensembl Gene: | OMIM ID: 617096 |
| Drug and gene relationship at DGIdb | |||
Expression of TMEM59L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TMEM59L | 25789 | 219005_at | -0.1264 | 0.5838 | |
| GSE20347 | TMEM59L | 25789 | 219005_at | -0.0516 | 0.5562 | |
| GSE23400 | TMEM59L | 25789 | 219005_at | -0.2273 | 0.0000 | |
| GSE26886 | TMEM59L | 25789 | 219005_at | 0.4476 | 0.0012 | |
| GSE29001 | TMEM59L | 25789 | 219005_at | -0.1804 | 0.1934 | |
| GSE38129 | TMEM59L | 25789 | 219005_at | -0.1840 | 0.0126 | |
| GSE45670 | TMEM59L | 25789 | 219005_at | 0.0242 | 0.8073 | |
| GSE63941 | TMEM59L | 25789 | 219005_at | 0.1640 | 0.5218 | |
| GSE77861 | TMEM59L | 25789 | 219005_at | 0.0179 | 0.9391 | |
| GSE97050 | TMEM59L | 25789 | A_33_P3302245 | -0.1255 | 0.8444 | |
| SRP133303 | TMEM59L | 25789 | RNAseq | -1.2930 | 0.0059 | |
| SRP159526 | TMEM59L | 25789 | RNAseq | 0.4765 | 0.6001 | |
| SRP219564 | TMEM59L | 25789 | RNAseq | 0.6645 | 0.4480 | |
| TCGA | TMEM59L | 25789 | RNAseq | -0.8681 | 0.0492 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by TMEM59L expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of TMEM59L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TMEM59L | 25789 | 4 | 5 | 21 | |
| GSE20123 | TMEM59L | 25789 | 3 | 3 | 24 | |
| GSE43470 | TMEM59L | 25789 | 2 | 5 | 36 | |
| GSE46452 | TMEM59L | 25789 | 47 | 1 | 11 | |
| GSE47630 | TMEM59L | 25789 | 4 | 8 | 28 | |
| GSE54993 | TMEM59L | 25789 | 15 | 4 | 51 | |
| GSE54994 | TMEM59L | 25789 | 6 | 13 | 34 | |
| GSE60625 | TMEM59L | 25789 | 9 | 0 | 2 | |
| GSE74703 | TMEM59L | 25789 | 2 | 3 | 31 | |
| GSE74704 | TMEM59L | 25789 | 0 | 3 | 17 | |
| TCGA | TMEM59L | 25789 | 16 | 10 | 70 |
Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.
Somatic mutations of TMEM59L:
Generating mutation plots.
Highly correlated genes for TMEM59L:
Showing top 20/1067 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TMEM59L | OPTC | 0.761311 | 3 | 0 | 3 |
| TMEM59L | FAM181B | 0.75744 | 3 | 0 | 3 |
| TMEM59L | ASB10 | 0.743014 | 3 | 0 | 3 |
| TMEM59L | SLC8A3 | 0.740045 | 3 | 0 | 3 |
| TMEM59L | NPR2 | 0.729167 | 3 | 0 | 3 |
| TMEM59L | RIMS4 | 0.728922 | 4 | 0 | 4 |
| TMEM59L | C19orf44 | 0.721446 | 3 | 0 | 3 |
| TMEM59L | WDR90 | 0.713673 | 3 | 0 | 3 |
| TMEM59L | GRIN1 | 0.712959 | 9 | 0 | 9 |
| TMEM59L | KCNH3 | 0.712561 | 4 | 0 | 4 |
| TMEM59L | TMEM52 | 0.710269 | 3 | 0 | 3 |
| TMEM59L | WDR87 | 0.70944 | 3 | 0 | 3 |
| TMEM59L | GPR62 | 0.707975 | 4 | 0 | 3 |
| TMEM59L | RASGRP4 | 0.707929 | 3 | 0 | 3 |
| TMEM59L | PPP1R12C | 0.707699 | 4 | 0 | 3 |
| TMEM59L | SLCO1A2 | 0.704467 | 3 | 0 | 3 |
| TMEM59L | CDR2L | 0.703592 | 3 | 0 | 3 |
| TMEM59L | SP7 | 0.701496 | 3 | 0 | 3 |
| TMEM59L | RNF151 | 0.700087 | 5 | 0 | 4 |
| TMEM59L | TULP2 | 0.697167 | 6 | 0 | 6 |
For details and further investigation, click here
