OR2F2

 

Full name: olfactory receptor family 2 subfamily F member 2 Alias Symbol: OR7-1
Type: protein-coding gene Cytoband: 7q35
Entrez ID: 135948 HGNC ID: HGNC:8247 Ensembl Gene: ENSG00000221910 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR2F2 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR2F2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 OR2F2 135948 217302_at -0.0815 0.7944
GSE20347 OR2F2 135948 217302_at -0.0765 0.1073
GSE23400 OR2F2 135948 217302_at -0.0170 0.3831
GSE26886 OR2F2 135948 217302_at -0.0588 0.5738
GSE29001 OR2F2 135948 217302_at -0.1626 0.2343
GSE38129 OR2F2 135948 217302_at -0.0648 0.1435
GSE45670 OR2F2 135948 217302_at -0.0645 0.3308
GSE63941 OR2F2 135948 217302_at 0.0140 0.9315
GSE77861 OR2F2 135948 217302_at -0.0707 0.3637

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by OR2F2 expression:

 

TCGA

 

Note: Click image to view full size file.  


Copy number change of OR2F2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR2F2 135948 3 2 25
GSE20123 OR2F2 135948 3 2 25
GSE43470 OR2F2 135948 3 4 36
GSE46452 OR2F2 135948 7 2 50
GSE47630 OR2F2 135948 6 8 26
GSE54993 OR2F2 135948 3 4 63
GSE54994 OR2F2 135948 5 8 40
GSE60625 OR2F2 135948 0 0 11
GSE74703 OR2F2 135948 2 4 30
GSE74704 OR2F2 135948 1 2 17
TCGA OR2F2 135948 27 27 42

Total number of gains: 60; Total number of losses: 63; Total Number of normals: 365.  


 

Somatic mutations of OR2F2:

 

Generating mutation plots.

 

Highly correlated genes for OR2F2:

 

Showing top 20/175 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR2F2EGR40.701708303
OR2F2FOXN3-AS20.699292303
OR2F2CDRT10.690269303
OR2F2OR7C20.68261303
OR2F2C3orf360.673611303
OR2F2NR6A10.670973303
OR2F2CHRD0.670445303
OR2F2CLDN60.663864303
OR2F2FGF60.659197303
OR2F2ATF70.658411303
OR2F2WNT8B0.653718303
OR2F2ART10.650146403
OR2F2CHRNA40.648989503
OR2F2CHRNB10.64789303
OR2F2OR10C10.645904303
OR2F2KIAA16140.643758403
OR2F2AMHR20.641749303
OR2F2MAPK110.640664303
OR2F2FSCN30.632003403
OR2F2OR2S20.629918403

For details and further investigation, click here