| Full name: Wnt family member 8B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 7479 | HGNC ID: HGNC:12789 | Ensembl Gene: ENSG00000075290 | OMIM ID: 601396 |
| Drug and gene relationship at DGIdb | |||
WNT8B involved pathways:
Expression of WNT8B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WNT8B | 7479 | 207612_at | 0.1329 | 0.5995 | |
| GSE20347 | WNT8B | 7479 | 207612_at | -0.0306 | 0.6734 | |
| GSE23400 | WNT8B | 7479 | 207612_at | -0.1088 | 0.0095 | |
| GSE26886 | WNT8B | 7479 | 207612_at | 0.0262 | 0.8422 | |
| GSE29001 | WNT8B | 7479 | 207612_at | -0.2463 | 0.1724 | |
| GSE38129 | WNT8B | 7479 | 207612_at | -0.0150 | 0.8233 | |
| GSE45670 | WNT8B | 7479 | 207612_at | -0.1181 | 0.2251 | |
| GSE53622 | WNT8B | 7479 | 10530 | 0.7099 | 0.0001 | |
| GSE53624 | WNT8B | 7479 | 10530 | 0.6866 | 0.0000 | |
| GSE63941 | WNT8B | 7479 | 207612_at | 0.1670 | 0.2179 | |
| GSE77861 | WNT8B | 7479 | 207612_at | 0.0495 | 0.6405 | |
| TCGA | WNT8B | 7479 | RNAseq | 0.4384 | 0.5167 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WNT8B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WNT8B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WNT8B | 7479 | 1 | 8 | 21 | |
| GSE20123 | WNT8B | 7479 | 1 | 7 | 22 | |
| GSE43470 | WNT8B | 7479 | 0 | 7 | 36 | |
| GSE46452 | WNT8B | 7479 | 0 | 11 | 48 | |
| GSE47630 | WNT8B | 7479 | 2 | 14 | 24 | |
| GSE54993 | WNT8B | 7479 | 8 | 0 | 62 | |
| GSE54994 | WNT8B | 7479 | 1 | 12 | 40 | |
| GSE60625 | WNT8B | 7479 | 0 | 0 | 11 | |
| GSE74703 | WNT8B | 7479 | 0 | 5 | 31 | |
| GSE74704 | WNT8B | 7479 | 0 | 4 | 16 | |
| TCGA | WNT8B | 7479 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of WNT8B:
Generating mutation plots.
Highly correlated genes for WNT8B:
Showing top 20/328 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WNT8B | INSL5 | 0.707175 | 3 | 0 | 3 |
| WNT8B | NLGN3 | 0.703197 | 3 | 0 | 3 |
| WNT8B | GLI1 | 0.702142 | 3 | 0 | 3 |
| WNT8B | ESRRB | 0.681843 | 3 | 0 | 3 |
| WNT8B | AQP2 | 0.678313 | 4 | 0 | 4 |
| WNT8B | PDE3B | 0.675493 | 3 | 0 | 3 |
| WNT8B | OR2S2 | 0.659352 | 4 | 0 | 4 |
| WNT8B | CNGB3 | 0.659224 | 4 | 0 | 4 |
| WNT8B | EPN1 | 0.659219 | 5 | 0 | 4 |
| WNT8B | CACNG1 | 0.656798 | 4 | 0 | 3 |
| WNT8B | OR2F2 | 0.653718 | 3 | 0 | 3 |
| WNT8B | SLC12A3 | 0.652425 | 3 | 0 | 3 |
| WNT8B | PROX1 | 0.652352 | 5 | 0 | 4 |
| WNT8B | INCENP | 0.650536 | 3 | 0 | 3 |
| WNT8B | BLK | 0.649806 | 3 | 0 | 3 |
| WNT8B | UNC93B1 | 0.649485 | 3 | 0 | 3 |
| WNT8B | IL1RAPL1 | 0.640011 | 3 | 0 | 3 |
| WNT8B | CCDC78 | 0.639516 | 3 | 0 | 3 |
| WNT8B | CALCB | 0.639112 | 3 | 0 | 3 |
| WNT8B | HTR6 | 0.63863 | 6 | 0 | 5 |
For details and further investigation, click here
