| Full name: angiomotin like 1 | Alias Symbol: JEAP | ||
| Type: protein-coding gene | Cytoband: 11q21 | ||
| Entrez ID: 154810 | HGNC ID: HGNC:17811 | Ensembl Gene: ENSG00000166025 | OMIM ID: 614657 |
| Drug and gene relationship at DGIdb | |||
Expression of AMOTL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AMOTL1 | 154810 | 225450_at | -0.4901 | 0.4570 | |
| GSE26886 | AMOTL1 | 154810 | 225450_at | -1.3462 | 0.0000 | |
| GSE45670 | AMOTL1 | 154810 | 225450_at | -0.5179 | 0.0004 | |
| GSE53622 | AMOTL1 | 154810 | 68610 | -0.3745 | 0.0013 | |
| GSE53624 | AMOTL1 | 154810 | 68610 | -0.2213 | 0.0120 | |
| GSE63941 | AMOTL1 | 154810 | 225450_at | -0.9548 | 0.2540 | |
| GSE77861 | AMOTL1 | 154810 | 225450_at | -0.2552 | 0.5884 | |
| GSE97050 | AMOTL1 | 154810 | A_24_P401768 | -0.5795 | 0.1143 | |
| SRP007169 | AMOTL1 | 154810 | RNAseq | 0.6268 | 0.2664 | |
| SRP008496 | AMOTL1 | 154810 | RNAseq | 0.7174 | 0.0295 | |
| SRP064894 | AMOTL1 | 154810 | RNAseq | -0.4596 | 0.0234 | |
| SRP133303 | AMOTL1 | 154810 | RNAseq | -0.7248 | 0.0012 | |
| SRP159526 | AMOTL1 | 154810 | RNAseq | -0.6135 | 0.1098 | |
| SRP193095 | AMOTL1 | 154810 | RNAseq | -0.3951 | 0.1008 | |
| SRP219564 | AMOTL1 | 154810 | RNAseq | -0.9158 | 0.1802 | |
| TCGA | AMOTL1 | 154810 | RNAseq | -0.0535 | 0.4869 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by AMOTL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AMOTL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AMOTL1 | 154810 | 3 | 9 | 18 | |
| GSE20123 | AMOTL1 | 154810 | 3 | 9 | 18 | |
| GSE43470 | AMOTL1 | 154810 | 2 | 5 | 36 | |
| GSE46452 | AMOTL1 | 154810 | 5 | 24 | 30 | |
| GSE47630 | AMOTL1 | 154810 | 2 | 19 | 19 | |
| GSE54993 | AMOTL1 | 154810 | 8 | 2 | 60 | |
| GSE54994 | AMOTL1 | 154810 | 7 | 18 | 28 | |
| GSE60625 | AMOTL1 | 154810 | 0 | 3 | 8 | |
| GSE74703 | AMOTL1 | 154810 | 1 | 4 | 31 | |
| GSE74704 | AMOTL1 | 154810 | 3 | 5 | 12 | |
| TCGA | AMOTL1 | 154810 | 11 | 43 | 42 |
Total number of gains: 45; Total number of losses: 141; Total Number of normals: 302.
Somatic mutations of AMOTL1:
Generating mutation plots.
Highly correlated genes for AMOTL1:
Showing top 20/453 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AMOTL1 | HOXA3 | 0.814539 | 3 | 0 | 3 |
| AMOTL1 | CCNYL1 | 0.790729 | 3 | 0 | 3 |
| AMOTL1 | TMOD1 | 0.770031 | 3 | 0 | 3 |
| AMOTL1 | NKX6-1 | 0.763924 | 3 | 0 | 3 |
| AMOTL1 | FAM120AOS | 0.76054 | 3 | 0 | 3 |
| AMOTL1 | TUBB6 | 0.747592 | 3 | 0 | 3 |
| AMOTL1 | HOXB2 | 0.74751 | 3 | 0 | 3 |
| AMOTL1 | TIMP4 | 0.747351 | 3 | 0 | 3 |
| AMOTL1 | HOXA4 | 0.743487 | 4 | 0 | 3 |
| AMOTL1 | PPIC | 0.740718 | 3 | 0 | 3 |
| AMOTL1 | MYOM2 | 0.736933 | 3 | 0 | 3 |
| AMOTL1 | ROCK1 | 0.736932 | 4 | 0 | 4 |
| AMOTL1 | METTL9 | 0.734466 | 3 | 0 | 3 |
| AMOTL1 | SCAMP2 | 0.732192 | 3 | 0 | 3 |
| AMOTL1 | MTMR6 | 0.731768 | 4 | 0 | 3 |
| AMOTL1 | CYP4V2 | 0.730479 | 3 | 0 | 3 |
| AMOTL1 | KLF4 | 0.729402 | 3 | 0 | 3 |
| AMOTL1 | PPARGC1A | 0.72906 | 3 | 0 | 3 |
| AMOTL1 | FECH | 0.728762 | 3 | 0 | 3 |
| AMOTL1 | CGGBP1 | 0.72848 | 4 | 0 | 3 |
For details and further investigation, click here
