| Full name: olfactory receptor family 7 subfamily A member 5 | Alias Symbol: HTPCR2 | ||
| Type: protein-coding gene | Cytoband: 19p13.1 | ||
| Entrez ID: 26659 | HGNC ID: HGNC:8368 | Ensembl Gene: ENSG00000188269 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
OR7A5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04740 | Olfactory transduction |
Expression of OR7A5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OR7A5 | 26659 | 208285_at | 0.3551 | 0.4976 | |
| GSE20347 | OR7A5 | 26659 | 208285_at | 0.1223 | 0.2466 | |
| GSE23400 | OR7A5 | 26659 | 208285_at | -0.0520 | 0.2685 | |
| GSE26886 | OR7A5 | 26659 | 208285_at | 0.7078 | 0.1333 | |
| GSE29001 | OR7A5 | 26659 | 208285_at | 0.2722 | 0.2846 | |
| GSE38129 | OR7A5 | 26659 | 208285_at | 0.0908 | 0.2962 | |
| GSE45670 | OR7A5 | 26659 | 208285_at | 0.1472 | 0.3696 | |
| GSE53622 | OR7A5 | 26659 | 9720 | 0.3364 | 0.0928 | |
| GSE53624 | OR7A5 | 26659 | 25628 | 0.7070 | 0.0000 | |
| GSE63941 | OR7A5 | 26659 | 208285_at | 0.1784 | 0.1782 | |
| GSE77861 | OR7A5 | 26659 | 208285_at | 0.1246 | 0.3721 | |
| SRP133303 | OR7A5 | 26659 | RNAseq | -0.0662 | 0.8569 | |
| SRP159526 | OR7A5 | 26659 | RNAseq | 3.0351 | 0.0003 | |
| SRP219564 | OR7A5 | 26659 | RNAseq | 2.5765 | 0.0028 | |
| TCGA | OR7A5 | 26659 | RNAseq | 5.2565 | 0.0000 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by OR7A5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OR7A5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OR7A5 | 26659 | 4 | 2 | 24 | |
| GSE20123 | OR7A5 | 26659 | 3 | 1 | 26 | |
| GSE43470 | OR7A5 | 26659 | 2 | 6 | 35 | |
| GSE46452 | OR7A5 | 26659 | 47 | 1 | 11 | |
| GSE47630 | OR7A5 | 26659 | 4 | 7 | 29 | |
| GSE54993 | OR7A5 | 26659 | 15 | 4 | 51 | |
| GSE54994 | OR7A5 | 26659 | 6 | 13 | 34 | |
| GSE60625 | OR7A5 | 26659 | 9 | 0 | 2 | |
| GSE74703 | OR7A5 | 26659 | 2 | 4 | 30 | |
| GSE74704 | OR7A5 | 26659 | 0 | 1 | 19 | |
| TCGA | OR7A5 | 26659 | 20 | 10 | 66 |
Total number of gains: 112; Total number of losses: 49; Total Number of normals: 327.
Somatic mutations of OR7A5:
Generating mutation plots.
Highly correlated genes for OR7A5:
Showing top 20/223 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OR7A5 | NEUROD2 | 0.684444 | 4 | 0 | 4 |
| OR7A5 | SOX12 | 0.655361 | 3 | 0 | 3 |
| OR7A5 | NRCAM | 0.646489 | 3 | 0 | 3 |
| OR7A5 | LUZP4 | 0.644622 | 5 | 0 | 5 |
| OR7A5 | EPOR | 0.63198 | 3 | 0 | 3 |
| OR7A5 | SLC27A1 | 0.62634 | 3 | 0 | 3 |
| OR7A5 | DGKD | 0.622635 | 4 | 0 | 3 |
| OR7A5 | KIR3DL3 | 0.618232 | 5 | 0 | 4 |
| OR7A5 | DAPK2 | 0.614626 | 4 | 0 | 3 |
| OR7A5 | SOX2-OT | 0.610084 | 4 | 0 | 3 |
| OR7A5 | SCN11A | 0.609899 | 5 | 0 | 3 |
| OR7A5 | TNFSF8 | 0.608637 | 4 | 0 | 4 |
| OR7A5 | CD22 | 0.605516 | 4 | 0 | 4 |
| OR7A5 | SSX1 | 0.605257 | 4 | 0 | 3 |
| OR7A5 | SLCO1C1 | 0.604719 | 4 | 0 | 3 |
| OR7A5 | LBP | 0.602806 | 6 | 0 | 5 |
| OR7A5 | LINC01352 | 0.602602 | 3 | 0 | 3 |
| OR7A5 | FOXN3-AS2 | 0.602153 | 4 | 0 | 4 |
| OR7A5 | UPB1 | 0.601267 | 4 | 0 | 4 |
| OR7A5 | CATSPERB | 0.60119 | 4 | 0 | 3 |
For details and further investigation, click here
