| Full name: solute carrier family 27 member 1 | Alias Symbol: FATP1|FATP|MGC71751|FLJ00336|ACSVL5 | ||
| Type: protein-coding gene | Cytoband: 19p13.11 | ||
| Entrez ID: 376497 | HGNC ID: HGNC:10995 | Ensembl Gene: ENSG00000130304 | OMIM ID: 600691 |
| Drug and gene relationship at DGIdb | |||
SLC27A1 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa03320 | PPAR signaling pathway |
Expression of SLC27A1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC27A1 | 376497 | 226728_at | 0.3061 | 0.4838 | |
| GSE26886 | SLC27A1 | 376497 | 226728_at | 0.4144 | 0.0028 | |
| GSE45670 | SLC27A1 | 376497 | 226728_at | -0.0227 | 0.8954 | |
| GSE53622 | SLC27A1 | 376497 | 15684 | 0.6498 | 0.0000 | |
| GSE53624 | SLC27A1 | 376497 | 98114 | -0.1206 | 0.1134 | |
| GSE63941 | SLC27A1 | 376497 | 226728_at | -0.2749 | 0.4510 | |
| GSE77861 | SLC27A1 | 376497 | 226728_at | 0.1391 | 0.4450 | |
| GSE97050 | SLC27A1 | 376497 | A_33_P3292621 | 0.1579 | 0.4785 | |
| SRP007169 | SLC27A1 | 376497 | RNAseq | -0.0983 | 0.8768 | |
| SRP008496 | SLC27A1 | 376497 | RNAseq | 0.4536 | 0.2833 | |
| SRP064894 | SLC27A1 | 376497 | RNAseq | 0.3726 | 0.2671 | |
| SRP133303 | SLC27A1 | 376497 | RNAseq | -0.6155 | 0.0058 | |
| SRP193095 | SLC27A1 | 376497 | RNAseq | 0.1417 | 0.3956 | |
| SRP219564 | SLC27A1 | 376497 | RNAseq | 0.1574 | 0.6447 | |
| TCGA | SLC27A1 | 376497 | RNAseq | -0.2646 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC27A1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC27A1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC27A1 | 376497 | 4 | 4 | 22 | |
| GSE20123 | SLC27A1 | 376497 | 3 | 2 | 25 | |
| GSE43470 | SLC27A1 | 376497 | 2 | 6 | 35 | |
| GSE46452 | SLC27A1 | 376497 | 47 | 1 | 11 | |
| GSE47630 | SLC27A1 | 376497 | 4 | 8 | 28 | |
| GSE54993 | SLC27A1 | 376497 | 15 | 4 | 51 | |
| GSE54994 | SLC27A1 | 376497 | 6 | 14 | 33 | |
| GSE60625 | SLC27A1 | 376497 | 9 | 0 | 2 | |
| GSE74703 | SLC27A1 | 376497 | 2 | 4 | 30 | |
| GSE74704 | SLC27A1 | 376497 | 0 | 2 | 18 | |
| TCGA | SLC27A1 | 376497 | 17 | 9 | 70 |
Total number of gains: 109; Total number of losses: 54; Total Number of normals: 325.
Somatic mutations of SLC27A1:
Generating mutation plots.
Highly correlated genes for SLC27A1:
Showing top 20/145 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC27A1 | SLC6A3 | 0.790788 | 3 | 0 | 3 |
| SLC27A1 | MPP3 | 0.720578 | 3 | 0 | 3 |
| SLC27A1 | TBC1D10B | 0.701896 | 3 | 0 | 3 |
| SLC27A1 | POM121L12 | 0.697888 | 3 | 0 | 3 |
| SLC27A1 | LYG1 | 0.683279 | 3 | 0 | 3 |
| SLC27A1 | ARL8A | 0.683165 | 3 | 0 | 3 |
| SLC27A1 | MRPS2 | 0.679641 | 4 | 0 | 3 |
| SLC27A1 | PYGO2 | 0.674864 | 3 | 0 | 3 |
| SLC27A1 | CNOT3 | 0.673907 | 4 | 0 | 3 |
| SLC27A1 | SLC35G1 | 0.672515 | 4 | 0 | 3 |
| SLC27A1 | PRDM13 | 0.669492 | 5 | 0 | 5 |
| SLC27A1 | CHST10 | 0.667155 | 4 | 0 | 3 |
| SLC27A1 | SYCE1L | 0.666362 | 4 | 0 | 4 |
| SLC27A1 | POLD1 | 0.663493 | 4 | 0 | 3 |
| SLC27A1 | DPM3 | 0.66178 | 4 | 0 | 3 |
| SLC27A1 | ANAPC2 | 0.661557 | 4 | 0 | 4 |
| SLC27A1 | LCNL1 | 0.657294 | 3 | 0 | 3 |
| SLC27A1 | WRAP73 | 0.656419 | 3 | 0 | 3 |
| SLC27A1 | ZNF232 | 0.652576 | 4 | 0 | 3 |
| SLC27A1 | FAM24B | 0.652146 | 3 | 0 | 3 |
For details and further investigation, click here
