VKORC1L1

 

Full name: vitamin K epoxide reductase complex subunit 1 like 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 7q11.21
Entrez ID: 154807 HGNC ID: HGNC:21492 Ensembl Gene: ENSG00000196715 OMIM ID: 608838
Drug and gene relationship at DGIdb

 

Expression of VKORC1L1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 VKORC1L1 154807 224881_at 0.5204 0.2093
GSE26886 VKORC1L1 154807 224881_at 0.6164 0.0108
GSE45670 VKORC1L1 154807 224881_at -0.0091 0.9716
GSE53622 VKORC1L1 154807 140232 0.5861 0.0000
GSE53624 VKORC1L1 154807 140232 0.9167 0.0000
GSE63941 VKORC1L1 154807 224881_at -0.3825 0.4331
GSE77861 VKORC1L1 154807 224881_at 0.3090 0.1066
GSE97050 VKORC1L1 154807 A_23_P413815 0.5394 0.1581
SRP007169 VKORC1L1 154807 RNAseq 0.7343 0.0249
SRP008496 VKORC1L1 154807 RNAseq 0.8209 0.0000
SRP064894 VKORC1L1 154807 RNAseq 0.4243 0.0013
SRP133303 VKORC1L1 154807 RNAseq 0.5094 0.0001
SRP159526 VKORC1L1 154807 RNAseq 0.5181 0.0617
SRP193095 VKORC1L1 154807 RNAseq 0.3333 0.0227
SRP219564 VKORC1L1 154807 RNAseq 0.2386 0.3542
TCGA VKORC1L1 154807 RNAseq 0.0331 0.5644

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by VKORC1L1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of VKORC1L1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 VKORC1L1 154807 11 2 17
GSE20123 VKORC1L1 154807 10 2 18
GSE43470 VKORC1L1 154807 2 1 40
GSE46452 VKORC1L1 154807 13 0 46
GSE47630 VKORC1L1 154807 7 1 32
GSE54993 VKORC1L1 154807 2 7 61
GSE54994 VKORC1L1 154807 12 4 37
GSE60625 VKORC1L1 154807 0 0 11
GSE74703 VKORC1L1 154807 2 1 33
GSE74704 VKORC1L1 154807 5 1 14
TCGA VKORC1L1 154807 47 6 43

Total number of gains: 111; Total number of losses: 25; Total Number of normals: 352.  

 

Somatic mutations of VKORC1L1:

 

Generating mutation plots.

 

Highly correlated genes for VKORC1L1:

 

Showing top 20/817 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
VKORC1L1PCGF60.773554303
VKORC1L1BRCA10.703127404
VKORC1L1CDK10.696068504
VKORC1L1TIGD70.695057303
VKORC1L1NABP20.693926404
VKORC1L1TTYH30.689569303
VKORC1L1FOXM10.684224505
VKORC1L1PNPT10.681205606
VKORC1L1MAPKAPK50.674205504
VKORC1L1OSBPL110.673329303
VKORC1L1ZXDB0.673114303
VKORC1L1KIF140.67309505
VKORC1L1KIF2C0.666266504
VKORC1L1MTERF10.665521303
VKORC1L1DBR10.665402403
VKORC1L1RNPS10.664968404
VKORC1L1MMP120.663198404
VKORC1L1RNF130.662864404
VKORC1L1SNAP470.662759303
VKORC1L1DDHD10.658096505

For details and further investigation, click here