| Full name: oxysterol binding protein like 5 | Alias Symbol: KIAA1534|ORP5|OBPH1 | ||
| Type: protein-coding gene | Cytoband: 11p15.4 | ||
| Entrez ID: 114879 | HGNC ID: HGNC:16392 | Ensembl Gene: ENSG00000021762 | OMIM ID: 606733 |
| Drug and gene relationship at DGIdb | |||
Expression of OSBPL5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OSBPL5 | 114879 | 233734_s_at | 0.0214 | 0.9574 | |
| GSE26886 | OSBPL5 | 114879 | 223464_at | 0.5542 | 0.0113 | |
| GSE45670 | OSBPL5 | 114879 | 233734_s_at | -0.0168 | 0.8782 | |
| GSE53622 | OSBPL5 | 114879 | 16153 | -0.2555 | 0.0043 | |
| GSE53624 | OSBPL5 | 114879 | 16153 | -0.0102 | 0.9066 | |
| GSE63941 | OSBPL5 | 114879 | 233734_s_at | -0.4829 | 0.0464 | |
| GSE77861 | OSBPL5 | 114879 | 233734_s_at | -0.1140 | 0.5429 | |
| GSE97050 | OSBPL5 | 114879 | A_33_P3394972 | -0.1968 | 0.3313 | |
| SRP007169 | OSBPL5 | 114879 | RNAseq | 0.2602 | 0.6379 | |
| SRP008496 | OSBPL5 | 114879 | RNAseq | 0.6487 | 0.1463 | |
| SRP064894 | OSBPL5 | 114879 | RNAseq | 0.1900 | 0.3248 | |
| SRP133303 | OSBPL5 | 114879 | RNAseq | -0.1104 | 0.6320 | |
| SRP159526 | OSBPL5 | 114879 | RNAseq | -0.2290 | 0.4273 | |
| SRP193095 | OSBPL5 | 114879 | RNAseq | 0.2926 | 0.0510 | |
| SRP219564 | OSBPL5 | 114879 | RNAseq | 0.2492 | 0.6425 | |
| TCGA | OSBPL5 | 114879 | RNAseq | -0.1944 | 0.0028 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OSBPL5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OSBPL5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OSBPL5 | 114879 | 1 | 11 | 18 | |
| GSE20123 | OSBPL5 | 114879 | 1 | 12 | 17 | |
| GSE43470 | OSBPL5 | 114879 | 1 | 10 | 32 | |
| GSE46452 | OSBPL5 | 114879 | 7 | 8 | 44 | |
| GSE47630 | OSBPL5 | 114879 | 4 | 12 | 24 | |
| GSE54993 | OSBPL5 | 114879 | 3 | 1 | 66 | |
| GSE54994 | OSBPL5 | 114879 | 1 | 12 | 40 | |
| GSE60625 | OSBPL5 | 114879 | 0 | 0 | 11 | |
| GSE74703 | OSBPL5 | 114879 | 1 | 8 | 27 | |
| GSE74704 | OSBPL5 | 114879 | 0 | 8 | 12 | |
| TCGA | OSBPL5 | 114879 | 7 | 40 | 49 |
Total number of gains: 26; Total number of losses: 122; Total Number of normals: 340.
Somatic mutations of OSBPL5:
Generating mutation plots.
Highly correlated genes for OSBPL5:
Showing top 20/160 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OSBPL5 | DNAH9 | 0.839727 | 3 | 0 | 3 |
| OSBPL5 | NOX1 | 0.825765 | 3 | 0 | 3 |
| OSBPL5 | CEND1 | 0.79029 | 3 | 0 | 3 |
| OSBPL5 | RLN3 | 0.768016 | 3 | 0 | 3 |
| OSBPL5 | RAD52 | 0.76133 | 3 | 0 | 3 |
| OSBPL5 | HOXB9 | 0.759763 | 3 | 0 | 3 |
| OSBPL5 | TLE6 | 0.753891 | 3 | 0 | 3 |
| OSBPL5 | BSND | 0.752213 | 3 | 0 | 3 |
| OSBPL5 | OR1F1 | 0.742876 | 3 | 0 | 3 |
| OSBPL5 | ZMYND10 | 0.740297 | 3 | 0 | 3 |
| OSBPL5 | CA4 | 0.736393 | 3 | 0 | 3 |
| OSBPL5 | TUT1 | 0.72699 | 4 | 0 | 3 |
| OSBPL5 | TMPRSS5 | 0.724664 | 3 | 0 | 3 |
| OSBPL5 | NTNG2 | 0.721466 | 4 | 0 | 3 |
| OSBPL5 | VEPH1 | 0.716774 | 3 | 0 | 3 |
| OSBPL5 | LY6H | 0.712084 | 3 | 0 | 3 |
| OSBPL5 | OPRD1 | 0.711487 | 4 | 0 | 3 |
| OSBPL5 | SP7 | 0.701779 | 3 | 0 | 3 |
| OSBPL5 | NPPC | 0.701428 | 3 | 0 | 3 |
| OSBPL5 | KCNF1 | 0.69966 | 4 | 0 | 3 |
For details and further investigation, click here
