| Full name: lymphocyte antigen 6 family member H | Alias Symbol: NMLY6 | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 4062 | HGNC ID: HGNC:6728 | Ensembl Gene: ENSG00000176956 | OMIM ID: 603625 |
| Drug and gene relationship at DGIdb | |||
Expression of LY6H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LY6H | 4062 | 206773_at | -0.3800 | 0.3087 | |
| GSE20347 | LY6H | 4062 | 206773_at | -0.1004 | 0.0946 | |
| GSE23400 | LY6H | 4062 | 206773_at | -0.0413 | 0.0618 | |
| GSE26886 | LY6H | 4062 | 206773_at | 0.0012 | 0.9906 | |
| GSE29001 | LY6H | 4062 | 206773_at | 0.0681 | 0.6896 | |
| GSE38129 | LY6H | 4062 | 206773_at | -0.1525 | 0.2389 | |
| GSE45670 | LY6H | 4062 | 206773_at | -0.1373 | 0.1135 | |
| GSE53622 | LY6H | 4062 | 61947 | -0.1708 | 0.1217 | |
| GSE53624 | LY6H | 4062 | 61947 | -0.1204 | 0.2296 | |
| GSE63941 | LY6H | 4062 | 206773_at | 0.0420 | 0.7741 | |
| GSE77861 | LY6H | 4062 | 206773_at | -0.0822 | 0.5181 | |
| GSE97050 | LY6H | 4062 | A_23_P134914 | -0.2658 | 0.3412 | |
| TCGA | LY6H | 4062 | RNAseq | -2.5785 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by LY6H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LY6H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LY6H | 4062 | 17 | 1 | 12 | |
| GSE20123 | LY6H | 4062 | 17 | 1 | 12 | |
| GSE43470 | LY6H | 4062 | 17 | 2 | 24 | |
| GSE46452 | LY6H | 4062 | 27 | 0 | 32 | |
| GSE47630 | LY6H | 4062 | 23 | 1 | 16 | |
| GSE54993 | LY6H | 4062 | 0 | 25 | 45 | |
| GSE54994 | LY6H | 4062 | 39 | 1 | 13 | |
| GSE60625 | LY6H | 4062 | 3 | 4 | 4 | |
| GSE74703 | LY6H | 4062 | 15 | 1 | 20 | |
| GSE74704 | LY6H | 4062 | 10 | 0 | 10 | |
| TCGA | LY6H | 4062 | 64 | 2 | 30 |
Total number of gains: 232; Total number of losses: 38; Total Number of normals: 218.
Somatic mutations of LY6H:
Generating mutation plots.
Highly correlated genes for LY6H:
Showing top 20/248 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LY6H | PICK1 | 0.770641 | 3 | 0 | 3 |
| LY6H | IGLON5 | 0.764532 | 3 | 0 | 3 |
| LY6H | TRAPPC9 | 0.759575 | 3 | 0 | 3 |
| LY6H | JAKMIP1 | 0.75373 | 3 | 0 | 3 |
| LY6H | CRYBB3 | 0.752216 | 3 | 0 | 3 |
| LY6H | RNF123 | 0.751874 | 3 | 0 | 3 |
| LY6H | SLC6A3 | 0.746791 | 3 | 0 | 3 |
| LY6H | SLC22A12 | 0.745738 | 3 | 0 | 3 |
| LY6H | CEBPE | 0.73619 | 3 | 0 | 3 |
| LY6H | ZNF221 | 0.729126 | 3 | 0 | 3 |
| LY6H | MOB2 | 0.728145 | 3 | 0 | 3 |
| LY6H | SLC45A1 | 0.724548 | 3 | 0 | 3 |
| LY6H | CLCNKB | 0.724313 | 3 | 0 | 3 |
| LY6H | VCX2 | 0.723855 | 3 | 0 | 3 |
| LY6H | ITGA10 | 0.717236 | 3 | 0 | 3 |
| LY6H | IGSF22 | 0.713261 | 3 | 0 | 3 |
| LY6H | OSBPL5 | 0.712084 | 3 | 0 | 3 |
| LY6H | RSPO1 | 0.707724 | 3 | 0 | 3 |
| LY6H | SRD5A2 | 0.702704 | 4 | 0 | 4 |
| LY6H | FUZ | 0.700213 | 4 | 0 | 3 |
For details and further investigation, click here
