| Full name: otospiralin | Alias Symbol: OTOSP | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 150677 | HGNC ID: HGNC:22644 | Ensembl Gene: ENSG00000178602 | OMIM ID: 607877 |
| Drug and gene relationship at DGIdb | |||
Expression of OTOS:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OTOS | 150677 | 242883_at | 0.1239 | 0.5557 | |
| GSE26886 | OTOS | 150677 | 242883_at | 0.4302 | 0.0036 | |
| GSE45670 | OTOS | 150677 | 242883_at | 0.1502 | 0.0507 | |
| GSE53622 | OTOS | 150677 | 72881 | -0.1819 | 0.0045 | |
| GSE53624 | OTOS | 150677 | 72881 | -0.1234 | 0.0557 | |
| GSE63941 | OTOS | 150677 | 242883_at | 0.0035 | 0.9893 | |
| GSE77861 | OTOS | 150677 | 242883_at | 0.0177 | 0.8785 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OTOS expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OTOS:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OTOS | 150677 | 1 | 12 | 17 | |
| GSE20123 | OTOS | 150677 | 1 | 12 | 17 | |
| GSE43470 | OTOS | 150677 | 1 | 9 | 33 | |
| GSE46452 | OTOS | 150677 | 0 | 5 | 54 | |
| GSE47630 | OTOS | 150677 | 4 | 5 | 31 | |
| GSE54993 | OTOS | 150677 | 3 | 3 | 64 | |
| GSE54994 | OTOS | 150677 | 8 | 9 | 36 | |
| GSE60625 | OTOS | 150677 | 0 | 3 | 8 | |
| GSE74703 | OTOS | 150677 | 1 | 7 | 28 | |
| GSE74704 | OTOS | 150677 | 1 | 5 | 14 | |
| TCGA | OTOS | 150677 | 11 | 29 | 56 |
Total number of gains: 31; Total number of losses: 99; Total Number of normals: 358.
Somatic mutations of OTOS:
Generating mutation plots.
Highly correlated genes for OTOS:
Showing top 20/36 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OTOS | PEX16 | 0.747479 | 3 | 0 | 3 |
| OTOS | SUGP1 | 0.688884 | 3 | 0 | 3 |
| OTOS | CAMKK1 | 0.653475 | 3 | 0 | 3 |
| OTOS | MARK4 | 0.644994 | 3 | 0 | 3 |
| OTOS | ADAMTSL2 | 0.640785 | 3 | 0 | 3 |
| OTOS | CCNE1 | 0.639212 | 3 | 0 | 3 |
| OTOS | SOX12 | 0.633497 | 3 | 0 | 3 |
| OTOS | TNFRSF9 | 0.62323 | 3 | 0 | 3 |
| OTOS | MICAL1 | 0.620135 | 3 | 0 | 3 |
| OTOS | IGF2-AS | 0.617403 | 3 | 0 | 3 |
| OTOS | DNAJC30 | 0.616719 | 3 | 0 | 3 |
| OTOS | SRP19 | 0.614697 | 3 | 0 | 3 |
| OTOS | GSK3A | 0.607429 | 4 | 0 | 3 |
| OTOS | TMEM179 | 0.607392 | 3 | 0 | 3 |
| OTOS | ARHGAP4 | 0.607097 | 3 | 0 | 3 |
| OTOS | ATP2B2 | 0.598041 | 4 | 0 | 3 |
| OTOS | BFSP1 | 0.589944 | 3 | 0 | 3 |
| OTOS | KIAA1614-AS1 | 0.586679 | 4 | 0 | 3 |
| OTOS | CHST13 | 0.577412 | 3 | 0 | 3 |
| OTOS | FAM193B | 0.576995 | 3 | 0 | 3 |
For details and further investigation, click here
